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1988 21
1989 14
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1994 14
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1999 20
2000 15
2001 5
2002 14
2003 14
2004 12
2005 15
2006 13
2007 11
2008 9
2009 7
2010 11
2011 10
2012 10
2013 14
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785 results

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Page 1
Levetiracetam Versus Phenobarbital for Neonatal Seizures: A Randomized Controlled Trial.
Sharpe C, Reiner GE, Davis SL, Nespeca M, Gold JJ, Rasmussen M, Kuperman R, Harbert MJ, Michelson D, Joe P, Wang S, Rismanchi N, Le NM, Mower A, Kim J, Battin MR, Lane B, Honold J, Knodel E, Arnell K, Bridge R, Lee L, Ernstrom K, Raman R, Haas RH; NEOLEV2 INVESTIGATORS. Sharpe C, et al. Pediatrics. 2020 Jun;145(6):e20193182. doi: 10.1542/peds.2019-3182. Epub 2020 May 8. Pediatrics. 2020. PMID: 32385134 Free PMC article. Clinical Trial.
Our objectives were to study the efficacy and safety of levetiracetam compared with phenobarbital as a first-line treatment of neonatal seizures. METHODS: The study was a multicenter, randomized, blinded, controlled, phase IIb trial investigating the efficacy and safety of …
Our objectives were to study the efficacy and safety of levetiracetam compared with phenobarbital as a first-line treatment of neonat …
Phenobarbital for acute alcohol withdrawal: a prospective randomized double-blind placebo-controlled study.
Rosenson J, Clements C, Simon B, Vieaux J, Graffman S, Vahidnia F, Cisse B, Lam J, Alter H. Rosenson J, et al. J Emerg Med. 2013 Mar;44(3):592-598.e2. doi: 10.1016/j.jemermed.2012.07.056. Epub 2012 Sep 19. J Emerg Med. 2013. PMID: 22999778 Clinical Trial.
Patients that received phenobarbital had fewer ICU admissions (8% vs. 25%, 95% confidence interval 4-32). There were no differences in adverse events. CONCLUSIONS: A single dose of i.v. phenobarbital combined with a symptom-guided lorazepam-based alcohol withdrawal …
Patients that received phenobarbital had fewer ICU admissions (8% vs. 25%, 95% confidence interval 4-32). There were no differences i …
A comparison of four treatments for generalized convulsive status epilepticus. Veterans Affairs Status Epilepticus Cooperative Study Group.
Treiman DM, Meyers PD, Walton NY, Collins JF, Colling C, Rowan AJ, Handforth A, Faught E, Calabrese VP, Uthman BM, Ramsay RE, Mamdani MB. Treiman DM, et al. N Engl J Med. 1998 Sep 17;339(12):792-8. doi: 10.1056/NEJM199809173391202. N Engl J Med. 1998. PMID: 9738086 Free article. Clinical Trial.
In this group, lorazepam was successful in 64.9 percent of those assigned to receive it, phenobarbital in 58.2 percent, diazepam plus phenytoin in 55.8 percent, and phenytoin in 43.6 percent (P=0.02 for the overall comparison among the four groups). ...Although lorazepam i …
In this group, lorazepam was successful in 64.9 percent of those assigned to receive it, phenobarbital in 58.2 percent, diazepam plus …
A Randomized Controlled Trial of Phenobarbital and Levetiracetam in Childhood Epilepsy.
Akter N, Rahman MM, Akhter S, Fatema K. Akter N, et al. Mymensingh Med J. 2018 Oct;27(4):776-784. Mymensingh Med J. 2018. PMID: 30487494 Clinical Trial.
The children were followed up for 12 months at 3 months interval to compare the seizure remission and side effects of Levetiracetam and Phenobarbital. The children in levetiracetam group was about 10 months older along with older age of onset of seizure (p=0.02) than those …
The children were followed up for 12 months at 3 months interval to compare the seizure remission and side effects of Levetiracetam and P …
Comparison of the effect of phenobarbital & levetiracetam in the treatment of neonatal abstinence syndrome (NAS) as adjuvant treatment in neonates admitted to the neonatal intensive care unit: a randomized clinical trial.
Jamali Z, Molaei-Farsangi MH, Ahmadipour H, Bahmanbijari B, Sabzevari F, Parizi ZD. Jamali Z, et al. BMC Pregnancy Childbirth. 2024 Apr 5;24(1):242. doi: 10.1186/s12884-024-06433-y. BMC Pregnancy Childbirth. 2024. PMID: 38580935 Free PMC article. Clinical Trial.
This study seeks the comparison of the effects of phenobarbital & levetiracetam as adjuvant therapy in neonatal abstinence syndrome. METHODS: This randomized clinical trial was performed in one year from May 2021 until May 2022. ...The infants who were diagnosed with u …
This study seeks the comparison of the effects of phenobarbital & levetiracetam as adjuvant therapy in neonatal abstinence syndro …
Long-term follow-up of phenobarbital versus valproate for generalized convulsive status epilepticus in adults: A randomized clinical trial.
Liu G, Wang Y, Tian F, Jiang M, Huang H, Chen W, Zhang Y, Su Y. Liu G, et al. Epilepsy Res. 2023 Sep;195:107187. doi: 10.1016/j.eplepsyres.2023.107187. Epub 2023 Jul 8. Epilepsy Res. 2023. PMID: 37467704 Free article. Clinical Trial.
Mild cognitive impairment was found in 7.14% of phenobarbital group and 50.0% in valproate group (P = 0.026). In addition, there were no significant differences with respect to anxiety (36.36% vs. 38.10%) and depression (31.82% vs. 47.62%) between the phenobarbital …
Mild cognitive impairment was found in 7.14% of phenobarbital group and 50.0% in valproate group (P = 0.026). In addition, there were …
Pharmacokinetics and clinical efficacy of phenobarbital in asphyxiated newborns treated with hypothermia: a thermopharmacological approach.
van den Broek MP, Groenendaal F, Toet MC, van Straaten HL, van Hasselt JG, Huitema AD, de Vries LS, Egberts AC, Rademaker CM. van den Broek MP, et al. Clin Pharmacokinet. 2012 Oct 1;51(10):671-9. doi: 10.1007/s40262-012-0004-y. Clin Pharmacokinet. 2012. PMID: 23018530 Clinical Trial.
We studied the effect of therapeutic hypothermia on the pharmacokinetics of phenobarbital in asphyxiated neonates, and the clinical efficacy and the effect of phenobarbital on the continuous amplitude-integrated electroencephalography (aEEG) in a prospective study. …
We studied the effect of therapeutic hypothermia on the pharmacokinetics of phenobarbital in asphyxiated neonates, and the clinical e …
Phenobarbital and propranolol in essential tremor: a double-blind controlled clinical trial.
Baruzzi A, Procaccianti G, Martinelli P, Riva R, Denoth F, Montanaro N, Lugaresi E. Baruzzi A, et al. Neurology. 1983 Mar;33(3):296-300. doi: 10.1212/wnl.33.3.296. Neurology. 1983. PMID: 6338416 Clinical Trial.
In a double-blind study with Latin square design, phenobarbital (about 1.3 mg per kilogram), propranolol (about 1.7 mg per kilogram), and placebo were given orally for 1 month to 12 patients with essential tremor. ...Patients' subjective evaluation and tremor amplitude mea …
In a double-blind study with Latin square design, phenobarbital (about 1.3 mg per kilogram), propranolol (about 1.7 mg per kilogram), …
The effect of acidic beverage versus mineral water on the change in serum phenobarbital concentrations: a randomized clinical trial on children with seizure.
Tavasolizadeh M, Hasanpour K, Nazarzadeh M, Mahdian D, Gholami O. Tavasolizadeh M, et al. Int J Neurosci. 2021 May;131(5):478-481. doi: 10.1080/00207454.2020.1748619. Epub 2020 Apr 15. Int J Neurosci. 2021. PMID: 32216594 Clinical Trial.
OBJECTIVE: To assess the effect of an acidic beverage (Orange juice) on the change in serum Phenobarbital concentrations in children with seizure who take Phenobarbital as the main treatment. ...The high-performance liquid chromatographic system was used for measure …
OBJECTIVE: To assess the effect of an acidic beverage (Orange juice) on the change in serum Phenobarbital concentrations in children …
Pharmacokinetics and clinical effect of phenobarbital in children with severe falciparum malaria and convulsions.
Kokwaro GO, Ogutu BR, Muchohi SN, Otieno GO, Newton CR. Kokwaro GO, et al. Br J Clin Pharmacol. 2003 Oct;56(4):453-7. doi: 10.1046/j.1365-2125.2003.01951.x. Br J Clin Pharmacol. 2003. PMID: 12968992 Free PMC article. Clinical Trial.
We evaluated a 15-mg kg(-1) intravenous (i.v.) dose of phenobarbital to determine its pharmacokinetics and clinical effects in children with severe falciparum malaria and status epilepticus. METHODS: Twelve children (M/F: 11/1), aged 7-62 months, received a loading dose of …
We evaluated a 15-mg kg(-1) intravenous (i.v.) dose of phenobarbital to determine its pharmacokinetics and clinical effects in childr …
785 results