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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 5
1947 11
1948 8
1949 3
1950 21
1951 11
1952 6
1953 14
1954 16
1955 12
1956 15
1957 12
1958 23
1959 14
1960 20
1961 21
1962 27
1963 67
1964 103
1965 83
1966 92
1967 169
1968 177
1969 255
1970 291
1971 304
1972 333
1973 445
1974 443
1975 437
1976 415
1977 398
1978 400
1979 396
1980 423
1981 450
1982 386
1983 477
1984 462
1985 459
1986 435
1987 384
1988 360
1989 394
1990 406
1991 351
1992 356
1993 320
1994 317
1995 347
1996 318
1997 319
1998 326
1999 350
2000 300
2001 279
2002 287
2003 257
2004 296
2005 298
2006 300
2007 295
2008 294
2009 275
2010 298
2011 316
2012 317
2013 338
2014 349
2015 353
2016 347
2017 294
2018 292
2019 276
2020 305
2021 309
2022 317
2023 213
2024 236
2025 261
2026 128

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19,750 results

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Page 1
Phenytoin - An anti-seizure drug: Overview of its chemistry, pharmacology and toxicology.
Patocka J, Wu Q, Nepovimova E, Kuca K. Patocka J, et al. Food Chem Toxicol. 2020 Aug;142:111393. doi: 10.1016/j.fct.2020.111393. Epub 2020 May 4. Food Chem Toxicol. 2020. PMID: 32376339 Review.
The narrow therapeutic index of phenytoin and its ubiquitous daily use pose a high risk of poisoning. This review article focuses on the chemistry, pharmacokinetics, and toxicology of phenytoin, with a special focus on its mutagenicity, carcinogenicity, and teratoge …
The narrow therapeutic index of phenytoin and its ubiquitous daily use pose a high risk of poisoning. This review article focuses on …
Fosphenytoin.
Luer MS. Luer MS. Neurol Res. 1998 Mar;20(2):178-82. doi: 10.1080/01616412.1998.11740502. Neurol Res. 1998. PMID: 9522355 Review.
Fosphenytoin is a phenytoin prodrug that has been introduced to overcome some of the problems and limitations associated with parenteral phenytoin sodium administration. Fosphenytoin is a phosphate ester prodrug that is converted to phenytoin in vivo by perip …
Fosphenytoin is a phenytoin prodrug that has been introduced to overcome some of the problems and limitations associated with parente …
Fosphenytoin.
Eriksson K, Keränen T, Kälviäinen R. Eriksson K, et al. Expert Opin Drug Metab Toxicol. 2009 Jun;5(6):695-701. doi: 10.1517/17425250902997975. Expert Opin Drug Metab Toxicol. 2009. PMID: 19473113 Review.
BACKGROUND: Fosphenytoin, phosphate ester pro-drug of phenytoin, was developed to overcome complications associated with parenteral phenytoin administration in treatment of acute symptomatic seizures, short-term prophylaxis and treatment of repetitive or prolonged s …
BACKGROUND: Fosphenytoin, phosphate ester pro-drug of phenytoin, was developed to overcome complications associated with parenteral …
Fosphenytoin (Cerebyx).
Browne TR. Browne TR. Clin Neuropharmacol. 1997 Feb;20(1):1-12. doi: 10.1097/00002826-199702000-00001. Clin Neuropharmacol. 1997. PMID: 9037568 Review.
Fosphenytoin is a phosphate ester prodrug of phenytoin developed as a replacement for standard injectable sodium phenytoin. After absorption, phenytoin is cleaved (conversion half-life 8-15 min) from fosphenytoin. Unlike phenytoin, fosphenytoin is free …
Fosphenytoin is a phosphate ester prodrug of phenytoin developed as a replacement for standard injectable sodium phenytoin. Af …
Phenytoin revisited.
Finkel MJ. Finkel MJ. Clin Ther. 1984;6(5):577-91. Clin Ther. 1984. PMID: 6383610 Review.
Phenytoin has a wide range of pharmacologic effects other than its anticonvulsant activity. ...Based on phenytoin's pharmacologic effects in animals, controlled trials of the drug appear to be warranted in cerebral ischemia and stroke, spinal cord injury, ang …
Phenytoin has a wide range of pharmacologic effects other than its anticonvulsant activity. ...Based on phenytoin's pha …
Phenytoin-folic acid interaction.
Lewis DP, Van Dyke DC, Willhite LA, Stumbo PJ, Berg MJ. Lewis DP, et al. Ann Pharmacother. 1995 Jul-Aug;29(7-8):726-35. doi: 10.1177/106002809502907-816. Ann Pharmacother. 1995. PMID: 8520091 Review.
STUDY SELECTION: All human studies examining the effects of phenytoin on serum folate concentrations and folic acid supplementation on serum phenytoin concentrations were selected. ...Phenytoin and folic acid therapy initiated concomitantly prevents decreased …
STUDY SELECTION: All human studies examining the effects of phenytoin on serum folate concentrations and folic acid supplementation o …
Phenytoin: neuroprotection or neurotoxicity?
Keppel Hesselink JM, Kopsky DJ. Keppel Hesselink JM, et al. Neurol Sci. 2017 Jun;38(6):1137-1141. doi: 10.1007/s10072-017-2993-7. Epub 2017 May 11. Neurol Sci. 2017. PMID: 28497312 Review.
Phenytoin is an 80-year young molecule and new indications are still emerging. The neuroprotective potential of phenytoin has been evaluated for decades. ...Clear toxically-induced phenytoin-related polyneuropathies, however, are extremely rare and are always …
Phenytoin is an 80-year young molecule and new indications are still emerging. The neuroprotective potential of phenytoin has …
Diphenylhydantoin.
Glazko AJ. Glazko AJ. Pharmacology. 1972;8(1):163-77. doi: 10.1159/000135282. Pharmacology. 1972. PMID: 4630160 No abstract available.
[Phenytoin].
Furuno K, Kawasaki H, Gomita Y. Furuno K, et al. Nihon Rinsho. 1995 Feb;53 Su Pt 1:924-7. Nihon Rinsho. 1995. PMID: 8753589 Review. Japanese. No abstract available.
19,750 results
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