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Over-the-counter laxative polyethylene glycol 3350: an evidence-based appraisal.
Zurad EG, Johanson JF. Zurad EG, et al. Curr Med Res Opin. 2011 Jul;27(7):1439-52. doi: 10.1185/03007995.2011.580339. Epub 2011 May 23. Curr Med Res Opin. 2011. PMID: 21604961 Review.
RESULTS: Twenty-one studies involving a total of 1949 patients were included in the overall review of polyethylene glycol 3350. Fifteen studies used randomized designs, eight were comparative trials, seven were conducted in pediatric populations, and three ha …
RESULTS: Twenty-one studies involving a total of 1949 patients were included in the overall review of polyethylene glycol 3
OTC polyethylene glycol 3350 and pharmacists' role in managing constipation.
Horn JR, Mantione MM, Johanson JF. Horn JR, et al. J Am Pharm Assoc (2003). 2012 May-Jun;52(3):372-80. doi: 10.1331/JAPhA.2012.10161. J Am Pharm Assoc (2003). 2012. PMID: 22618979 Review.
OBJECTIVES: To define constipation, assess the pharmacist's role in identifying and treating constipation, and review clinical evidence for the efficacy, safety, and tolerability of polyethylene glycol (PEG) 3350 (MiraLAX-Merck Consumer Care), an osmotic laxa …
OBJECTIVES: To define constipation, assess the pharmacist's role in identifying and treating constipation, and review clinical evidence for …
Polyethylene glycol 3350 plus electrolytes for pediatric chronic constipation: An open-label clinical study in Japan.
Gondo M, Nagata S, Shinbo K, Oota A, Tomomasa T. Gondo M, et al. Pediatr Int. 2020 May;62(5):600-608. doi: 10.1111/ped.14102. Epub 2020 Apr 27. Pediatr Int. 2020. PMID: 31845426 Free PMC article. Clinical Trial.
BACKGROUND: Despite the abundance of study evidence for its efficacy and tolerability for the treatment of constipation in other countries, polyethylene glycol 3350 plus electrolytes (PEG3350+E) was not available in Japan until recently. ...Stool consistency …
BACKGROUND: Despite the abundance of study evidence for its efficacy and tolerability for the treatment of constipation in other countries, …
PEG 3350 Versus Lactulose for Treatment of Functional Constipation in Children: Randomized Study.
Jarzebicka D, Sieczkowska-Golub J, Kierkus J, Czubkowski P, Kowalczuk-Kryston M, Pelc M, Lebensztejn D, Korczowski B, Socha P, Oracz G. Jarzebicka D, et al. J Pediatr Gastroenterol Nutr. 2019 Mar;68(3):318-324. doi: 10.1097/MPG.0000000000002192. J Pediatr Gastroenterol Nutr. 2019. PMID: 30383579 Clinical Trial.
OBJECTIVES: The aim of this study was to compare the clinical efficacy and tolerance of polyethylene glycol 3350 (PEG) and lactulose for the treatment of functional constipation in infants and children. ...CONCLUSIONS: PEG 3350 is more effective and ca …
OBJECTIVES: The aim of this study was to compare the clinical efficacy and tolerance of polyethylene glycol 3350 (PEG) …
Safety of polyethylene glycol 3350 solution in chronic constipation: randomized, placebo-controlled trial.
McGraw T. McGraw T. Clin Exp Gastroenterol. 2016 Jul 15;9:173-80. doi: 10.2147/CEG.S111693. eCollection 2016. Clin Exp Gastroenterol. 2016. PMID: 27486340 Free PMC article.
PURPOSE: To evaluate the safety and tolerability of aqueous solution concentrate (ASC) of polyethylene glycol (PEG) 3350 in patients with functional constipation. ...No serious AEs or deaths were reported, and no patient discontinued because of an AE. …
PURPOSE: To evaluate the safety and tolerability of aqueous solution concentrate (ASC) of polyethylene glycol (PEG) 3350
Polyethylene glycol 3350 for constipation in children with dysfunctional elimination.
Erickson BA, Austin JC, Cooper CS, Boyt MA. Erickson BA, et al. J Urol. 2003 Oct;170(4 Pt 2):1518-20. doi: 10.1097/01.ju.0000083730.70185.75. J Urol. 2003. PMID: 14501649
MATERIALS AND METHODS: We review our use of polyethylene glycol 3350 in 35 girls and 11 boys with dysfunctional elimination. ...CONCLUSIONS: The efficacy, compliance and lack of significant side effects make polyethylene glycol 3350
MATERIALS AND METHODS: We review our use of polyethylene glycol 3350 in 35 girls and 11 boys with dysfunctional elimina …
Randomised clinical trial: Polyethylene glycol 3350 with sports drink vs. polyethylene glycol with electrolyte solution as purgatives for colonoscopy--the incidence of hyponatraemia.
Matro R, Daskalakis C, Negoianu D, Katz L, Henry C, Share M, Kastenberg D. Matro R, et al. Aliment Pharmacol Ther. 2014 Sep;40(6):610-9. doi: 10.1111/apt.12884. Epub 2014 Jul 28. Aliment Pharmacol Ther. 2014. PMID: 25066025 Free article. Clinical Trial.
BACKGROUND: Polyethylene glycol 3350 plus sports drink (PEG-SD) is a hypo-osmotic purgative commonly used for colonoscopy, though little safety data are available. ...Changes in electrolytes from baseline were small but significantly worse with PEG-SD for sod …
BACKGROUND: Polyethylene glycol 3350 plus sports drink (PEG-SD) is a hypo-osmotic purgative commonly used for colonosco …
Polyethylene glycol 3350 plus electrolytes for chronic constipation: a 2-week, randomized, double-blind, placebo-controlled study with a 52-week open-label extension.
Nakajima A, Shinbo K, Oota A, Kinoshita Y. Nakajima A, et al. J Gastroenterol. 2019 Sep;54(9):792-803. doi: 10.1007/s00535-019-01581-x. Epub 2019 Apr 22. J Gastroenterol. 2019. PMID: 31011797 Free PMC article. Clinical Trial.
BACKGROUND: Although polyethylene glycol 3350 plus electrolytes (PEG3350 + E) is the most widely used osmotic laxative in Europe, prospective data on its long-term (over 6 months) safety and efficacy are not available to date. ...The primary efficacy endpoint …
BACKGROUND: Although polyethylene glycol 3350 plus electrolytes (PEG3350 + E) is the most widely used osmotic laxative …
Polyethylene Glycol 3350 and Docusate Sodium Compared With Docusate Sodium Alone After Urogynecologic Surgery: A Randomized Controlled Trial.
Edenfield AL, Siddiqui NY, Wu JM, Dieter AA, Garrett MA, Visco AG. Edenfield AL, et al. Obstet Gynecol. 2016 Sep;128(3):543-9. doi: 10.1097/AOG.0000000000001565. Obstet Gynecol. 2016. PMID: 27500338 Clinical Trial.
OBJECTIVE: To compare time to first bowel movement and additional gastrointestinal outcomes between women receiving polyethylene glycol 3350 (PEG3350) and docusate sodium and docusate sodium alone after urogynecologic surgery. ...RESULTS: From September 2012 …
OBJECTIVE: To compare time to first bowel movement and additional gastrointestinal outcomes between women receiving polyethylene g
A randomized, prospective, comparison study of polyethylene glycol 3350 without electrolytes and milk of magnesia for children with constipation and fecal incontinence.
Loening-Baucke V, Pashankar DS. Loening-Baucke V, et al. Pediatrics. 2006 Aug;118(2):528-35. doi: 10.1542/peds.2006-0220. Pediatrics. 2006. PMID: 16882804 Clinical Trial.
An intent-to-treat analysis was used. Safety was assessed with evaluation of clinical adverse effects and blood tests. RESULTS: Thirty-nine children were assigned randomly to receive polyethylene glycol and 40 to receive milk of magnesia. ...Polyeth
An intent-to-treat analysis was used. Safety was assessed with evaluation of clinical adverse effects and blood tests. RESULTS …
63 results