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62 results

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Page 1
Lactulose vs polyethylene glycol 3350--electrolyte solution for treatment of overt hepatic encephalopathy: the HELP randomized clinical trial.
Rahimi RS, Singal AG, Cuthbert JA, Rockey DC. Rahimi RS, et al. JAMA Intern Med. 2014 Nov;174(11):1727-33. doi: 10.1001/jamainternmed.2014.4746. JAMA Intern Med. 2014. PMID: 25243839 Free PMC article. Clinical Trial.
Pharmacologic treatment for acute (overt) HE has remained the same for decades. OBJECTIVE: To compare polyethylene glycol 3350-electrolyte solution (PEG) and lactulose treatments in patients with cirrhosis admitted to the hospital for HE. ...DESIGN, SETTING, …
Pharmacologic treatment for acute (overt) HE has remained the same for decades. OBJECTIVE: To compare polyethylene glycol 3 …
Efficacy, safety, and acceptability of polyethylene glycol 3350 without electrolytes vs magnesium hydroxide in functional constipation in children from six months to eighteen years of age: A controlled clinical trial.
Worona-Dibner L, Vázquez-Frias R, Valdez-Chávez L, Verdiguel-Oyola M. Worona-Dibner L, et al. Rev Gastroenterol Mex (Engl Ed). 2023 Apr-Jun;88(2):107-117. doi: 10.1016/j.rgmxen.2021.12.005. Epub 2021 Dec 24. Rev Gastroenterol Mex (Engl Ed). 2023. PMID: 34961695 Free article. Clinical Trial.
High-dose polyethylene glycol-3350 and gatorade solutions for patients with previous inadequate bowel preparations for colonoscopy are safe and effective.
Gerard DP, Gerard SF, Raiser MW. Gerard DP, et al. BMC Gastroenterol. 2023 May 11;23(1):146. doi: 10.1186/s12876-023-02663-0. BMC Gastroenterol. 2023. PMID: 37170191 Free PMC article. Clinical Trial.
Step 1: 1.5 times the standard-dose of polyethylene glycol 3350 (PEG, 459 g) and Gatorade; and Step 2: 2.0 times the standard-dose of PEG (612 g) and Gatorade, both were given as extended split-dose preparations. 69 outpatients consumed their preparation befo …
Step 1: 1.5 times the standard-dose of polyethylene glycol 3350 (PEG, 459 g) and Gatorade; and Step 2: 2.0 times the st …
Polyethylene glycol 3350 plus electrolytes for pediatric chronic constipation: An open-label clinical study in Japan.
Gondo M, Nagata S, Shinbo K, Oota A, Tomomasa T. Gondo M, et al. Pediatr Int. 2020 May;62(5):600-608. doi: 10.1111/ped.14102. Epub 2020 Apr 27. Pediatr Int. 2020. PMID: 31845426 Free PMC article. Clinical Trial.
BACKGROUND: Despite the abundance of study evidence for its efficacy and tolerability for the treatment of constipation in other countries, polyethylene glycol 3350 plus electrolytes (PEG3350+E) was not available in Japan until recently. ...
BACKGROUND: Despite the abundance of study evidence for its efficacy and tolerability for the treatment of constipation in other countries, …
Polyethylene Glycol 3350 and Docusate Sodium Compared With Docusate Sodium Alone After Urogynecologic Surgery: A Randomized Controlled Trial.
Edenfield AL, Siddiqui NY, Wu JM, Dieter AA, Garrett MA, Visco AG. Edenfield AL, et al. Obstet Gynecol. 2016 Sep;128(3):543-9. doi: 10.1097/AOG.0000000000001565. Obstet Gynecol. 2016. PMID: 27500338 Clinical Trial.
OBJECTIVE: To compare time to first bowel movement and additional gastrointestinal outcomes between women receiving polyethylene glycol 3350 (PEG3350) and docusate sodium and docusate sodium alone after urogynecologic surgery. ...RESULTS: From September 2012 …
OBJECTIVE: To compare time to first bowel movement and additional gastrointestinal outcomes between women receiving polyethylene g …
Clinical trial: single- and multiple-dose pharmacokinetics of polyethylene glycol (PEG-3350) in healthy young and elderly subjects.
Pelham RW, Nix LC, Chavira RE, Cleveland MV, Stetson P. Pelham RW, et al. Aliment Pharmacol Ther. 2008 Jul;28(2):256-65. doi: 10.1111/j.1365-2036.2008.03727.x. Epub 2008 Apr 30. Aliment Pharmacol Ther. 2008. PMID: 18462266 Clinical Trial.
BACKGROUND: The pharmacokinetics of polyethylene glycol 3350 (PEG-3350) have not been fully described because of lack of a sufficiently sensitive analytical method. ...
BACKGROUND: The pharmacokinetics of polyethylene glycol 3350 (PEG-3350) have not been fully described because of lack o …
Tolerance and efficacy of polyethylene glycol 3350/electrolyte solution versus lactulose in relieving opiate induced constipation: a double-blinded placebo-controlled trial.
Freedman MD, Schwartz HJ, Roby R, Fleisher S. Freedman MD, et al. J Clin Pharmacol. 1997 Oct;37(10):904-7. doi: 10.1002/j.1552-4604.1997.tb04264.x. J Clin Pharmacol. 1997. PMID: 9505981 Clinical Trial.

The efficacy of lactulose was compared with polyethylene glycol 3350/electrolyte solution for relief of methadone-induced constipation. ...Polyethylene glycol 3350/electrolyte solution produced the loosest stool (P < 0.0001) compared w

…
The efficacy of lactulose was compared with polyethylene glycol 3350/electrolyte solution for relief of methadone-induc …
Polyethylene Glycol 3350 in the Treatment of Chronic Idiopathic Constipation: Post hoc Analysis Using FDA Endpoints.
Menees SB, Lembo AJ, Chey WD. Menees SB, et al. Can J Gastroenterol Hepatol. 2022 Sep 9;2022:3533504. doi: 10.1155/2022/3533504. eCollection 2022. Can J Gastroenterol Hepatol. 2022. PMID: 36120087 Free PMC article. Clinical Trial.

RESULTS: The proportion of patients meeting the new endpoint was significantly higher with polyethylene glycol 3350 vs placebo (42% vs 13%; P < 0.0001). Reductions in the mean number of hard/lumpy stools/week (-2.1 vs -0.9; P = 0.0014) and the weekly mean

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RESULTS: The proportion of patients meeting the new endpoint was significantly higher with polyethylene glycol 3350 vs …
62 results