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Comparative study of posaconazole and voriconazole for primary antifungal prophylaxis in patients with pediatric acute leukemia.
Tu S, Zhang K, Wang N, Chu J, Yang L, Xie Z. Tu S, et al. Sci Rep. 2023 Nov 1;13(1):18789. doi: 10.1038/s41598-023-46328-0. Sci Rep. 2023. PMID: 37914820 Free PMC article.
Posaconazole and voriconazole are commonly used for preventing invasive fungal disease (IFD), but few studies compared posaconazole with voriconazole for primary antifungal prophylaxis (PAP) in pediatric acute leukemia. ...Posaconazole and voriconazole were c …
Posaconazole and voriconazole are commonly used for preventing invasive fungal disease (IFD), but few studies compared posaconazol …
Optimal Management of Refractory Crohn's Disease: Current Landscape and Future Direction.
Lee KE, Tu VY, Faye AS. Lee KE, et al. Clin Exp Gastroenterol. 2024 Mar 26;17:75-86. doi: 10.2147/CEG.S359376. eCollection 2024. Clin Exp Gastroenterol. 2024. PMID: 38558912 Free PMC article. Review.
We also describe evidence for emerging and alternative therapeutic modalities, including fecal microbiota transplant, exclusive enteral feeding, hyperbaric oxygen, stem cell therapy, bone marrow transplant, and posaconazole, with a focus on both the potential impact and sp …
We also describe evidence for emerging and alternative therapeutic modalities, including fecal microbiota transplant, exclusive enteral feed …
Synergistic effects of vorinostat (SAHA) and azoles against Aspergillus species and their biofilms.
Tu B, Yin G, Li H. Tu B, et al. BMC Microbiol. 2020 Feb 7;20(1):28. doi: 10.1186/s12866-020-1718-x. BMC Microbiol. 2020. PMID: 32028887 Free PMC article.
Here, we investigated the interactions of SAHA and itraconazole, voriconazole, and posaconazole against Aspergillus spp. in vitro using both planktonic cells and biofilms. RESULTS: We investigated 20 clinical strains using broth microdilution checkerboard methods. The resu …
Here, we investigated the interactions of SAHA and itraconazole, voriconazole, and posaconazole against Aspergillus spp. in vitro usi …
Successful treatment of resistant ocular fusariosis with posaconazole (SCH-56592).
Tu EY, McCartney DL, Beatty RF, Springer KL, Levy J, Edward D. Tu EY, et al. Am J Ophthalmol. 2007 Feb;143(2):222-227. doi: 10.1016/j.ajo.2006.10.048. Epub 2006 Dec 8. Am J Ophthalmol. 2007. PMID: 17258521
PURPOSE: To describe the successful treatment with systemic posaconazole of a series of Fusarium ocular infections refractory to other antifungal agents. ...All patients were treated with oral posaconazole and experienced rapid reduction of intraocular inflammation …
PURPOSE: To describe the successful treatment with systemic posaconazole of a series of Fusarium ocular infections refractory to othe …
Mixed Infection of Toe Nail Caused by Trichosporon asahii and Rhodotorula mucilaginosa.
Idris NFB, Huang G, Jia Q, Yuan L, Li Y, Tu Z. Idris NFB, et al. Mycopathologia. 2020 Apr;185(2):373-376. doi: 10.1007/s11046-019-00406-y. Epub 2019 Nov 23. Mycopathologia. 2020. PMID: 31760556
Direct microscopic examination, fungal culture and MALDI-TOF MS were employed in isolated pathogens; hence, antifungal susceptibility test was evaluated. T. asahii was sensitive to posaconazole, voriconazole and itraconazole, whereas R. mucilaginosa was sensitive to both 5 …
Direct microscopic examination, fungal culture and MALDI-TOF MS were employed in isolated pathogens; hence, antifungal susceptibility test w …
Agricultural systems as potential sources of emerging human mycoses caused by Trichoderma: a successful, common phylotype of Trichoderma longibrachiatum in the frontline.
Hatvani L, Homa M, Chenthamara K, Cai F, Kocsubé S, Atanasova L, Mlinaric-Missoni E, Manikandan P, Revathi R, Dóczi I, Bogáts G, Narendran V, Büchner R, Vágvölgyi C, Druzhinina IS, Kredics L. Hatvani L, et al. FEMS Microbiol Lett. 2019 Nov 1;366(21):fnz246. doi: 10.1093/femsle/fnz246. FEMS Microbiol Lett. 2019. PMID: 31816013
The majority of the isolates of both taxa could tolerate >256, >32 and >32 mug/ml fluconazole, itraconazole and posaconazole, respectively. None of the obtained results revealed characteristic differences between strains of clinical and agricultural origin, nor be …
The majority of the isolates of both taxa could tolerate >256, >32 and >32 mug/ml fluconazole, itraconazole and posaconazole …
Progressive Dispersion of Azole Resistance in Aspergillus fumigatus: Fatal Invasive Aspergillosis in a Patient with Acute Myeloid Leukemia Infected with an A. fumigatus Strain with a cyp51A TR46 Y121F M172I T289A Allele.
Rößler S, Bader O, Stölzel F, Sommer U, Spiess B, Geibel S, Buchheidt D, Groß U, Baretton G, Jacobs E, Ostrosky-Zeichner L. Rößler S, et al. Antimicrob Agents Chemother. 2017 Jul 25;61(8):e00270-17. doi: 10.1128/AAC.00270-17. Print 2017 Aug. Antimicrob Agents Chemother. 2017. PMID: 28743702 Free PMC article.
Here, we report a culture- and autopsy-proven fatal invasive aspergillosis in an allogeneic HSTC patient which he developed despite posaconazole prophylaxis. The agent was determined to be an azole-resistant Aspergillus fumigatus strain bearing the cyp51A mutation combinat …
Here, we report a culture- and autopsy-proven fatal invasive aspergillosis in an allogeneic HSTC patient which he developed despite posac …
Recalcitrant Beauveria bassiana keratitis: confocal microscopy findings and treatment with posaconazole (Noxafil).
Tu EY, Park AJ. Tu EY, et al. Cornea. 2007 Sep;26(8):1008-10. doi: 10.1097/ICO.0b013e3180de4953. Cornea. 2007. PMID: 17721308
The keratitis was unresponsive to multiple topical and systemic antifungals but resolved after the addition of oral posaconazole. CONCLUSIONS: B. bassiana is a rare cause of keratitis that may show significant resistance to topical and systemic antifungals but was treated …
The keratitis was unresponsive to multiple topical and systemic antifungals but resolved after the addition of oral posaconazole. CON …