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Page 1
Sodium zirconium cyclosilicate in hyperkalemia.
Packham DK, Rasmussen HS, Lavin PT, El-Shahawy MA, Roger SD, Block G, Qunibi W, Pergola P, Singh B. Packham DK, et al. N Engl J Med. 2015 Jan 15;372(3):222-31. doi: 10.1056/NEJMoa1411487. Epub 2014 Nov 21. N Engl J Med. 2015. PMID: 25415807 Free article. Clinical Trial.
BACKGROUND: Hyperkalemia (serum potassium level, >5.0 mmol per liter) is associated with increased mortality among patients with heart failure, chronic kidney disease, or diabetes. We investigated whether sodium zirconium cyclosilicate (ZS-9), a novel selective catio …
BACKGROUND: Hyperkalemia (serum potassium level, >5.0 mmol per liter) is associated with increased mortality among patients with h …
Potassium ion homeostasis modulates mitochondrial function.
Waite AJ, Rao B, Schinski E, Thayer NH, Hotz M, Lefebvre AEYT, Sandoval C, Gottschling DE. Waite AJ, et al. J Cell Biol. 2026 Apr 6;225(4):e202505110. doi: 10.1083/jcb.202505110. Epub 2026 Jan 13. J Cell Biol. 2026. PMID: 41528311 Free PMC article.
Characterization of the longest-lived mutant revealed that reduced internal potassium increased MMP and extended lifespan. Distinct interventions improved cellular MMP and lifespan: deleting a potassium transporter; altering the balance between kinases and phosphata …
Characterization of the longest-lived mutant revealed that reduced internal potassium increased MMP and extended lifespan. Distinct i …
Pathophysiology of red cell volume.
Browning JA, Ellory JC, Gibson JS. Browning JA, et al. Contrib Nephrol. 2006;152:241-268. doi: 10.1159/000096327. Contrib Nephrol. 2006. PMID: 17065816 Review.
Finally, a number of red cell stomatocytoses have been described where alterations to erythrocyte volume are the result of increased membrane cation permeability, in particular to Na(+) and K(+). The emerging significance of non-selective cation pathways is common t …
Finally, a number of red cell stomatocytoses have been described where alterations to erythrocyte volume are the result of increased membran …
The role of potassium on drought resistance of winter wheat cultivars under cold dryland conditions: Probed by chlorophyll a fluorescence.
Lotfi R, Abbasi A, Kalaji HM, Eskandari I, Sedghieh V, Khorsandi H, Sadeghian N, Yadav S, Rastogi A. Lotfi R, et al. Plant Physiol Biochem. 2022 Jul 1;182:45-54. doi: 10.1016/j.plaphy.2022.04.010. Epub 2022 Apr 14. Plant Physiol Biochem. 2022. PMID: 35462197 Free article.
Potassium (K) is an important cation that regulates plant metabolism. Therefore the effect of different concentrations of potassium (0, 75, 150 kg ha(-1) K(2)SO(4)) on photosynthesis efficiency of three winter wheat cultivars (Baran, Homa, Hashtrud) was inves …
Potassium (K) is an important cation that regulates plant metabolism. Therefore the effect of different concentrations of p …
Effects of hyperpolarization-activated channel blocker ZD7288 on polar excitations of frog sciatic nerve.
Matsuda Y, Ang FY, Nakajima K, Kogure S. Matsuda Y, et al. J Physiol Sci. 2008 Apr;58(2):99-104. doi: 10.2170/physiolsci.RP014707. Epub 2008 Feb 21. J Physiol Sci. 2008. PMID: 18284714 Free article.
When ZD7288 (1 mM) was applied, the amplitude of AE displayed a significant decrease after 30 min. When TTX or ZD7288 was applied to the middle portion between the stimulating and recording electrode grids, TTX showed the conduction block, but the latter yielded almost no …
When ZD7288 (1 mM) was applied, the amplitude of AE displayed a significant decrease after 30 min. When TTX or ZD7288 was applied to …
Salt-specific stability of short and charged alanine-based alpha-helices.
Dzubiella J. Dzubiella J. J Phys Chem B. 2009 Dec 31;113(52):16689-94. doi: 10.1021/jp9077932. J Phys Chem B. 2009. PMID: 19928870
The alpha-helical stability of the short and net-charged (+/-6e) alanine-based peptides (AE)(6) and (AK)(6) in approximately 2.5 M electrolyte solution (NaCl, KCl, NaI, and KI) is investigated by 1 micros long all-atom computer simulations. While the nonspecific screening …
The alpha-helical stability of the short and net-charged (+/-6e) alanine-based peptides (AE)(6) and (AK)(6) in approximately 2.5 M el …
Prion peptide fragment PrP[106-126] forms distinct cation channel types.
Kourie JI, Culverson A. Kourie JI, et al. J Neurosci Res. 2000 Oct 1;62(1):120-33. doi: 10.1002/1097-4547(20001001)62:1<120::AID-JNR13>3.0.CO;2-2. J Neurosci Res. 2000. PMID: 11002294
Based on the conductance and kinetic parameters of the single channel currents recorded in 250/50 mM KCl cis/trans we have found that the PrP[106-126]-formed heterogeneous cation channels that differ in their conductance and kinetic properties. The most frequently observed …
Based on the conductance and kinetic parameters of the single channel currents recorded in 250/50 mM KCl cis/trans we have found that the Pr …
The osmotic response of the isolated tectorial membrane of the chick to isosmotic solutions: effect of Na+, K+, and Ca2+ concentration.
Freeman DM, Cotanche DA, Ehsani F, Weiss TF. Freeman DM, et al. Hear Res. 1994 Sep;79(1-2):197-215. doi: 10.1016/0378-5955(94)90141-4. Hear Res. 1994. PMID: 7806483
Substitution of artificial perilymph (AP) for artificial endolymph (AE) caused a small (approximately 15%), slow (time constants tau approximately 12 min) shrinkage of the thickness of the tectorial membrane that was largely reversed on return to AE. Substitution of …
Substitution of artificial perilymph (AP) for artificial endolymph (AE) caused a small (approximately 15%), slow (time constants tau …
14 results