Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 3
2003 6
2004 8
2005 10
2006 7
2007 17
2008 24
2009 42
2010 43
2011 52
2012 52
2013 50
2014 63
2015 48
2016 52
2017 48
2018 43
2019 46
2020 34
2021 33
2022 34
2023 27
2024 10

Text availability

Article attribute

Article type

Publication date

Search Results

626 results

Results by year

Filters applied: . Clear all
Page 1
Comparison of amitriptyline supplemented with pregabalin, pregabalin supplemented with amitriptyline, and duloxetine supplemented with pregabalin for the treatment of diabetic peripheral neuropathic pain (OPTION-DM): a multicentre, double-blind, randomised crossover trial.
Tesfaye S, Sloan G, Petrie J, White D, Bradburn M, Julious S, Rajbhandari S, Sharma S, Rayman G, Gouni R, Alam U, Cooper C, Loban A, Sutherland K, Glover R, Waterhouse S, Turton E, Horspool M, Gandhi R, Maguire D, Jude EB, Ahmed SH, Vas P, Hariman C, McDougall C, Devers M, Tsatlidis V, Johnson M, Rice ASC, Bouhassira D, Bennett DL, Selvarajah D; OPTION-DM trial group. Tesfaye S, et al. Lancet. 2022 Aug 27;400(10353):680-690. doi: 10.1016/S0140-6736(22)01472-6. Epub 2022 Aug 22. Lancet. 2022. PMID: 36007534 Free PMC article. Clinical Trial.
Participants were randomly assigned (1:1:1:1:1:1), with a predetermined randomisation schedule stratified by site using permuted blocks of size six or 12, to receive one of six ordered sequences of the three treatment pathways: amitriptyline supplemented with pregabalin (A …
Participants were randomly assigned (1:1:1:1:1:1), with a predetermined randomisation schedule stratified by site using permuted blocks of s …
Comparing duloxetine and pregabalin for treatment of pain and depression in women with fibromyalgia: an open-label randomized clinical trial.
Bidari A, Moazen-Zadeh E, Ghavidel-Parsa B, Rahmani S, Hosseini S, Hassankhani A. Bidari A, et al. Daru. 2019 Jun;27(1):149-158. doi: 10.1007/s40199-019-00257-4. Epub 2019 Mar 14. Daru. 2019. PMID: 30877484 Free PMC article. Clinical Trial.
BACKGROUND: Duloxetine and pregabalin are among the most widely used medications in the treatment of patients with fibromyalgia syndrome (FM). ...Drop out rate and cumulative incidence of nausea was significantly higher in the duloxetine arm compared to the pregabalin
BACKGROUND: Duloxetine and pregabalin are among the most widely used medications in the treatment of patients with fibromyalgia syndr …
Effect of Gabapentin vs Pregabalin on Pain Intensity in Adults With Chronic Sciatica: A Randomized Clinical Trial.
Robertson K, Marshman LAG, Plummer D, Downs E. Robertson K, et al. JAMA Neurol. 2019 Jan 1;76(1):28-34. doi: 10.1001/jamaneurol.2018.3077. JAMA Neurol. 2019. PMID: 30326006 Free PMC article. Clinical Trial.
IMPORTANCE: Optimal pharmacologic treatment for chronic sciatica (CS) is currently unclear. While gabapentin (GBP) and pregabalin (PGB) are both used to treat CS, equipoise exists. Nevertheless, pharmaceutical regulation authorities typically subsidize one drug over the ot …
IMPORTANCE: Optimal pharmacologic treatment for chronic sciatica (CS) is currently unclear. While gabapentin (GBP) and pregabalin (PG …
Duloxetine and pregabalin: high-dose monotherapy or their combination? The "COMBO-DN study"--a multinational, randomized, double-blind, parallel-group study in patients with diabetic peripheral neuropathic pain.
Tesfaye S, Wilhelm S, Lledo A, Schacht A, Tölle T, Bouhassira D, Cruccu G, Skljarevski V, Freynhagen R. Tesfaye S, et al. Pain. 2013 Dec;154(12):2616-2625. doi: 10.1016/j.pain.2013.05.043. Epub 2013 May 31. Pain. 2013. PMID: 23732189 Free article. Clinical Trial.
For initial 8-week therapy, either 60 mg/day duloxetine (groups 1, 2) or 300 mg/day pregabalin (groups 3, 4) was given. Thereafter, in the 8-week combination/high-dose therapy period, only nonresponders received 120 mg/day duloxetine (group 1), a combination of 60 mg/day d …
For initial 8-week therapy, either 60 mg/day duloxetine (groups 1, 2) or 300 mg/day pregabalin (groups 3, 4) was given. Thereafter, i …
Optimal pharmacotherapy pathway in adults with diabetic peripheral neuropathic pain: the OPTION-DM RCT.
Tesfaye S, Sloan G, Petrie J, White D, Bradburn M, Young T, Rajbhandari S, Sharma S, Rayman G, Gouni R, Alam U, Julious SA, Cooper C, Loban A, Sutherland K, Glover R, Waterhouse S, Turton E, Horspool M, Gandhi R, Maguire D, Jude E, Ahmed SH, Vas P, Hariman C, McDougall C, Devers M, Tsatlidis V, Johnson M, Bouhassira D, Bennett DL, Selvarajah D. Tesfaye S, et al. Health Technol Assess. 2022 Oct;26(39):1-100. doi: 10.3310/RXUO6757. Health Technol Assess. 2022. PMID: 36259684 Free PMC article. Clinical Trial.
INTERVENTIONS: Participants were randomised to three commonly used treatment pathways: (1) amitriptyline supplemented with pregabalin, (2) duloxetine supplemented with pregabalin and (3) pregabalin supplemented with amitriptyline. ...The incremental gains in …
INTERVENTIONS: Participants were randomised to three commonly used treatment pathways: (1) amitriptyline supplemented with pregabalin
The Clinical Difference between Gabapentin and Pregabalin: Data from a Pilot Comparative Trial.
Gammoh O, Al-Smadi A, Shawagfeh MQ, Abadi T, Kasawneh J, Malkawi S, Zein S. Gammoh O, et al. Rev Recent Clin Trials. 2021;16(3):279-287. doi: 10.2174/1574887116666210201110507. Rev Recent Clin Trials. 2021. PMID: 33563173 Clinical Trial.
While pregabalin group showed a significantly lower pain score (p=0.039). The gabapentin group showed significant improvement in anxiety (p=0.001), insomnia (p=0.001), general fatigue (p=0.009), physical fatigue (p=0.001), reduce activity (p=0.001), and mental fatigue (p=0 …
While pregabalin group showed a significantly lower pain score (p=0.039). The gabapentin group showed significant improvement in anxi …
A randomized comparative study of methylcobalamin, methylcobalamin plus pregabalin and methylcobalamin plus duloxetine in patients of painful diabetic neuropathy.
Sharma C, Kaur I, Singh H, Grover IS, Singh J. Sharma C, et al. Indian J Pharmacol. 2021 Sep-Oct;53(5):358-363. doi: 10.4103/ijp.ijp_1159_20. Indian J Pharmacol. 2021. PMID: 34854403 Free PMC article. Clinical Trial.
AIMS: We aimed to study the efficacy, safety, and tolerability of methylcobalamin, methylcobalamin plus pregabalin, and methylcobalamin plus duloxetine in patients of painful diabetic neuropathy. ...MATERIALS AND METHODS: A total of 100 patients were recruited and randomiz …
AIMS: We aimed to study the efficacy, safety, and tolerability of methylcobalamin, methylcobalamin plus pregabalin, and methylcobalam …
Randomised clinical trial: the effects of pregabalin vs placebo on functional dyspepsia.
Kotikula I, Thinrungroj N, Pinyopornpanish K, Kijdamrongthum P, Leerapun A, Chitapanarux T, Thongsawat S, Praisontarangkul OA. Kotikula I, et al. Aliment Pharmacol Ther. 2021 Oct;54(8):1026-1032. doi: 10.1111/apt.16588. Epub 2021 Aug 30. Aliment Pharmacol Ther. 2021. PMID: 34460973 Clinical Trial.
Pregabalin improved the overall quality of life (P = 0.03). The most common adverse event with pregabalin was dizziness, occurring in 51.6% of patients. CONCLUSIONS: Pregabalin led to significant alleviation of dyspeptic symptoms, especially in patients with
Pregabalin improved the overall quality of life (P = 0.03). The most common adverse event with pregabalin was dizziness, occur
Perioperative Administration of Pregabalin and Esketamine to Prevent Chronic Pain After Breast Cancer Surgery: A Randomized Controlled Trial.
Wang M, Xiong HP, Sheng K, Sun XB, Zhao XQ, Liu QR. Wang M, et al. Drug Des Devel Ther. 2023 Jun 8;17:1699-1706. doi: 10.2147/DDDT.S413273. eCollection 2023. Drug Des Devel Ther. 2023. PMID: 37313456 Free PMC article. Clinical Trial.
This study aimed to investigate the efficacy of combined perioperative oral pregabalin and postoperative esketamine in preventing chronic pain after breast cancer surgery. METHODS: Ninety patients undergoing elective breast cancer surgery were randomized into the combined …
This study aimed to investigate the efficacy of combined perioperative oral pregabalin and postoperative esketamine in preventing chr …
Trial of Pregabalin for Acute and Chronic Sciatica.
Mathieson S, Maher CG, McLachlan AJ, Latimer J, Koes BW, Hancock MJ, Harris I, Day RO, Billot L, Pik J, Jan S, Lin CC. Mathieson S, et al. N Engl J Med. 2017 Mar 23;376(12):1111-1120. doi: 10.1056/NEJMoa1614292. N Engl J Med. 2017. PMID: 28328324 Free article. Clinical Trial.
This study examined whether pregabalin may reduce the intensity of sciatica. METHODS: We conducted a randomized, double-blind, placebo-controlled trial of pregabalin in patients with sciatica. ...RESULTS: A total of 209 patients underwent randomization, of whom 108 …
This study examined whether pregabalin may reduce the intensity of sciatica. METHODS: We conducted a randomized, double-blind, placeb …
626 results