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Year Number of Results
1965 1
1966 1
1967 2
1968 1
1969 1
1970 1
1971 1
1972 1
1973 3
1974 3
1975 6
1976 2
1979 2
1981 5
1982 2
1983 3
1984 1
1985 2
1986 4
1987 3
1988 2
1989 1
1990 2
1991 4
1993 2
1994 1
1995 3
1996 3
1997 1
1998 2
1999 2
2000 3
2002 3
2003 3
2004 1
2005 3
2006 3
2007 2
2008 1
2009 2
2022 0
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87 results
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Page 1
Barbiturate anticonvulsants in refractory affective disorders.
Hayes SG. Hayes SG. Ann Clin Psychiatry. 1993 Mar;5(1):35-44. doi: 10.3109/10401239309148922. Ann Clin Psychiatry. 1993. PMID: 8348197 Review.
In the present investigation, 27 seizure-free, affectively ill patients who received therapeutic trials of primidone and/or mephobarbital after failing on antidepressants, lithium, carbamazepine, valproate, and phenytoin were analyzed with regard to effects on illness seve …
In the present investigation, 27 seizure-free, affectively ill patients who received therapeutic trials of primidone and/or mephobarb …
Primidone and propranolol in essential tremor: a study based on quantitative tremor recording and plasma anticonvulsant levels.
Dietrichson P, Espen E. Dietrichson P, et al. Acta Neurol Scand. 1987 May;75(5):332-40. doi: 10.1111/j.1600-0404.1987.tb05455.x. Acta Neurol Scand. 1987. PMID: 2887081 Clinical Trial.
Primidone was compared to the unselective beta adrenoceptor antagonist propranolol in the suppression of essential tremor. ...Correlation analysis between the individual tremor amplitude reductions and plasma primidone concentrations showed on the second day a tende …
Primidone was compared to the unselective beta adrenoceptor antagonist propranolol in the suppression of essential tremor. ...Correla …
Clinical and electromyographic assessment of essential tremor treatment.
Milanov I. Milanov I. Parkinsonism Relat Disord. 2002 Jun;8(5):343-8. doi: 10.1016/s1353-8020(01)00038-4. Parkinsonism Relat Disord. 2002. PMID: 15177063 Clinical Trial.
The aim of this study was to reevaluate the effects of beta-blockers and primidone on essential tremor. We also aimed to evaluate the differential effects of beta-blockers and primidone on tremor with synchronous or alternating electromyographic activity and on trem …
The aim of this study was to reevaluate the effects of beta-blockers and primidone on essential tremor. We also aimed to evaluate the …
Comparison of carbamazepine, phenobarbital, phenytoin, and primidone in partial and secondarily generalized tonic-clonic seizures.
Mattson RH, Cramer JA, Collins JF, Smith DB, Delgado-Escueta AV, Browne TR, Williamson PD, Treiman DM, McNamara JO, McCutchen CB, et al. Mattson RH, et al. N Engl J Med. 1985 Jul 18;313(3):145-51. doi: 10.1056/NEJM198507183130303. N Engl J Med. 1985. PMID: 3925335 Clinical Trial.
Overall treatment success was highest with carbamazepine or phenytoin, intermediate with phenobarbital, and lowest with primidone (P less than 0.002). Differences in failure rates of the drugs were explained primarily by the fact that primidone caused more intolerab …
Overall treatment success was highest with carbamazepine or phenytoin, intermediate with phenobarbital, and lowest with primidone (P …
Interaction of phenytoin and primidone.
Reynolds EH, Fenton G, Fenwick P, Johnson AL, Laundy M. Reynolds EH, et al. Br Med J. 1975 Jun 14;2(5971):594-5. doi: 10.1136/bmj.2.5971.594. Br Med J. 1975. PMID: 1131627 Free PMC article. Clinical Trial.
The ratio of derived phenobarbitone to unmetabolized primidone in the serum was significantly higher in 50 epileptic patients on a combination of primidone and phenytoin than in 12 patients on primidone alone, though the dose and serum levels of primidone …
The ratio of derived phenobarbitone to unmetabolized primidone in the serum was significantly higher in 50 epileptic patients on a co …
Primidone is associated with interictal depression in patients with epilepsy.
Lopez-Gomez M, Ramirez-Bermudez J, Campillo C, Sosa AL, Espinola M, Ruiz I. Lopez-Gomez M, et al. Epilepsy Behav. 2005 May;6(3):413-6. doi: 10.1016/j.yebeh.2005.01.016. Epilepsy Behav. 2005. PMID: 15820351 Clinical Trial.
Factors associated in the bivariate analysis were: cryptogenic etiology, posttraumatic epilepsy, use of primidone, and inadequate seizure control. After logistic regression, inadequate seizure control (OR 3.08, 95% CI 1.40-6.77, P=0.005) and use of primidone (OR 4.0 …
Factors associated in the bivariate analysis were: cryptogenic etiology, posttraumatic epilepsy, use of primidone, and inadequate sei …
The "forgotten" cross-tolerance between phenobarbital and primidone: it can prevent acute primidone-related toxicity.
Kanner AM, Parra J, Frey M. Kanner AM, et al. Epilepsia. 2000 Oct;41(10):1310-4. doi: 10.1111/j.1528-1157.2000.tb04610.x. Epilepsia. 2000. PMID: 11051127 Free article. Clinical Trial.
All previous antiepileptic medications were tapered down to yield a primidone monotherapy regimen. RESULTS: Twenty-six patients (87%) tolerated the introduction of primidone with minimal or no adverse events. Only one patient had to discontinue primidone duri …
All previous antiepileptic medications were tapered down to yield a primidone monotherapy regimen. RESULTS: Twenty-six patients (87%) …
Adjuvant therapy of parkinsonian tremor.
Koller WC, Herbster G. Koller WC, et al. Arch Neurol. 1987 Sep;44(9):921-3. doi: 10.1001/archneur.1987.00520210023013. Arch Neurol. 1987. PMID: 3619710 Clinical Trial.
Mean tremor amplitudes were not changed by primidone or clonazepam. Tremor frequency was unaltered by the drugs. No side effects occurred with long-acting propranolol but adverse reactions were common with primidone and clonazepam. Long-acting propranolol is a usefu …
Mean tremor amplitudes were not changed by primidone or clonazepam. Tremor frequency was unaltered by the drugs. No side effects occu …
Primidone in essential tremor of the hands and head: a double blind controlled clinical study.
Findley LJ, Cleeves L, Calzetti S. Findley LJ, et al. J Neurol Neurosurg Psychiatry. 1985 Sep;48(9):911-5. doi: 10.1136/jnnp.48.9.911. J Neurol Neurosurg Psychiatry. 1985. PMID: 3900296 Free PMC article. Clinical Trial.
Primidone was significantly superior to placebo in reducing the magnitude of hand tremor, its efficacy being comparable to that of propranolol. ...An acute toxic reaction to an initial small dose (62.5 mg) of primidone was seen in six of 22 patients....
Primidone was significantly superior to placebo in reducing the magnitude of hand tremor, its efficacy being comparable to that of pr …
Disability in essential tremor: effect of treatment.
Koller W, Biary N, Cone S. Koller W, et al. Neurology. 1986 Jul;36(7):1001-4. doi: 10.1212/wnl.36.7.1001. Neurology. 1986. PMID: 2940473 Clinical Trial.
We studied 18 patients with essential tremor for difficulty with handwriting, drinking, eating, fine manipulations, and embarrassment. Propranolol and primidone reduced the amplitude of both postural and kinetic tremor. ...
We studied 18 patients with essential tremor for difficulty with handwriting, drinking, eating, fine manipulations, and embarrassment. Propr …
87 results