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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 4
1966 11
1967 9
1968 11
1969 8
1970 21
1971 21
1972 21
1973 14
1974 22
1975 17
1976 23
1977 21
1978 35
1979 33
1980 38
1981 21
1982 20
1983 39
1984 47
1985 51
1986 66
1987 75
1988 81
1989 101
1990 103
1991 120
1992 106
1993 131
1994 157
1995 173
1996 192
1997 163
1998 188
1999 212
2000 234
2001 212
2002 214
2003 212
2004 216
2005 239
2006 248
2007 255
2008 278
2009 248
2010 261
2011 251
2012 255
2013 249
2014 278
2015 223
2016 236
2017 232
2018 201
2019 151
2020 178
2021 155
2022 114
2023 89
2024 108
2025 17

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6,976 results

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Page 1
PROMISE: first-trimester progesterone therapy in women with a history of unexplained recurrent miscarriages - a randomised, double-blind, placebo-controlled, international multicentre trial and economic evaluation.
Coomarasamy A, Williams H, Truchanowicz E, Seed PT, Small R, Quenby S, Gupta P, Dawood F, Koot YE, Atik RB, Bloemenkamp KW, Brady R, Briley A, Cavallaro R, Cheong YC, Chu J, Eapen A, Essex H, Ewies A, Hoek A, Kaaijk EM, Koks CA, Li TC, MacLean M, Mol BW, Moore J, Parrott S, Ross JA, Sharpe L, Stewart J, Trépel D, Vaithilingam N, Farquharson RG, Kilby MD, Khalaf Y, Goddijn M, Regan L, Rai R. Coomarasamy A, et al. Health Technol Assess. 2016 May;20(41):1-92. doi: 10.3310/hta20410. Health Technol Assess. 2016. PMID: 27225013 Free PMC article. Clinical Trial.
BACKGROUND AND OBJECTIVES: Progesterone is essential to maintain a healthy pregnancy. Guidance from the Royal College of Obstetricians and Gynaecologists and a Cochrane review called for a definitive trial to test whether or not progesterone therapy in the first tri …
BACKGROUND AND OBJECTIVES: Progesterone is essential to maintain a healthy pregnancy. Guidance from the Royal College of Obstetrician …
Comparing cervical cerclage, pessary and vaginal progesterone for prevention of preterm birth in women with a short cervix (SuPPoRT): A multicentre randomised controlled trial.
Hezelgrave NL, Suff N, Seed P, Robinson V, Carter J, Watson H, Ridout A, David AL, Pereira S, Hoveyda F, Girling J, Vinayakarao L, Tribe RM, Shennan AH; SuPPoRT Collaborating Team. Hezelgrave NL, et al. PLoS Med. 2024 Jul 16;21(7):e1004427. doi: 10.1371/journal.pmed.1004427. eCollection 2024 Jul. PLoS Med. 2024. PMID: 39012912 Free PMC article. Clinical Trial.
The SuPPoRT "Stitch, Pessary, or Progesterone Randomised Trial" was designed to compare the rate of PTB <37 weeks between each intervention in women who develop a short cervix in pregnancy. ...Using binary regression, randomised therapies (cerclage versus pessary versus …
The SuPPoRT "Stitch, Pessary, or Progesterone Randomised Trial" was designed to compare the rate of PTB <37 weeks between each int …
A Phase III randomized controlled trial comparing the efficacy, safety and tolerability of oral dydrogesterone versus micronized vaginal progesterone for luteal support in in vitro fertilization.
Tournaye H, Sukhikh GT, Kahler E, Griesinger G. Tournaye H, et al. Hum Reprod. 2017 May 1;32(5):1019-1027. doi: 10.1093/humrep/dex023. Hum Reprod. 2017. PMID: 28333318 Free PMC article. Clinical Trial.
STUDY QUESTION: Is oral dydrogesterone 30 mg daily (10 mg three times daily [TID]) non-inferior to micronized vaginal progesterone (MVP) 600 mg daily (200 mg TID) for luteal support in in vitro fertilization (IVF), assessed by the presence of fetal heartbeats determined by …
STUDY QUESTION: Is oral dydrogesterone 30 mg daily (10 mg three times daily [TID]) non-inferior to micronized vaginal progesterone (M …
Addition of progesterone to feminizing gender-affirming hormone therapy in transgender individuals for breast development: a randomized controlled trial.
Dijkman BAM, Helder D, Boogers LS, Gieles NC, van Heesewijk JO, Slaa ST, Liberton NPTJ, Wiepjes CM, de Blok CJM, den Heijer M, Dreijerink KMA. Dijkman BAM, et al. BMC Pharmacol Toxicol. 2023 Dec 20;24(1):80. doi: 10.1186/s40360-023-00724-4. BMC Pharmacol Toxicol. 2023. PMID: 38124194 Free PMC article. Clinical Trial.
Therefore, transgender women often choose to undergo breast augmentation surgery. Progesterone is important for breast development in cisgender women during puberty. A potential role for progesterone in breast development in transgender women has not been investigat …
Therefore, transgender women often choose to undergo breast augmentation surgery. Progesterone is important for breast development in …
Progesterone and threatened abortion: a randomized clinical trial on endocervical cytokine concentrations.
Alimohamadi S, Javadian P, Gharedaghi MH, Javadian N, Alinia H, Khazardoust S, Borna S, Hantoushzadeh S. Alimohamadi S, et al. J Reprod Immunol. 2013 Jun;98(1-2):52-60. doi: 10.1016/j.jri.2013.01.004. Epub 2013 Mar 13. J Reprod Immunol. 2013. PMID: 23489467 Clinical Trial.
A significant decrease in IFNgamma and increase in IL-10 in endocervical fluid was seen when the values were compared before and after progesterone treatment. However, there were no significant differences in pregnancy outcomes between the placebo and progesterone g …
A significant decrease in IFNgamma and increase in IL-10 in endocervical fluid was seen when the values were compared before and after pr
Vaginal Progesterone for Pregnancy Prolongation After Arrested Preterm Labor: A Randomized Clinical Trial.
Nachum Z, Ganor Paz Y, Massalha M, Wated M, Harel N, Yefet E. Nachum Z, et al. JAMA Netw Open. 2024 Jul 1;7(7):e2419894. doi: 10.1001/jamanetworkopen.2024.19894. JAMA Netw Open. 2024. PMID: 38976270 Free PMC article. Clinical Trial.
A few clinical trials with considerable methodological limitations have demonstrated some efficacy for 400 mg vaginal micronized progesterone (VMP) in women with APTL. OBJECTIVE: To investigate the effectiveness of daily 400 mg VMP for the prolongation of pregnancy after A …
A few clinical trials with considerable methodological limitations have demonstrated some efficacy for 400 mg vaginal micronized progeste
Progesterone and Postpartum Smoking Relapse: A Pilot Double-Blind Placebo-Controlled Randomized Trial.
Allen SS, Allen AM, Lunos S, Tosun N. Allen SS, et al. Nicotine Tob Res. 2016 Nov;18(11):2145-2153. doi: 10.1093/ntr/ntw156. Epub 2016 Aug 18. Nicotine Tob Res. 2016. PMID: 27613934 Free PMC article. Clinical Trial.
This pilot study evaluates the feasibility and potential role of exogenous progesterone in postpartum smoking relapse. METHODS: This 12-week double-blind placebo-controlled randomized pilot trial randomized 46 abstinent postpartum women to active progesterone (PRO; …
This pilot study evaluates the feasibility and potential role of exogenous progesterone in postpartum smoking relapse. METHODS: This …
Early vaginal progesterone versus placebo in twin pregnancies for the prevention of spontaneous preterm birth: a randomized, double-blind trial.
Rehal A, Benkő Z, De Paco Matallana C, Syngelaki A, Janga D, Cicero S, Akolekar R, Singh M, Chaveeva P, Burgos J, Molina FS, Savvidou M, De La Calle M, Persico N, Quezada Rojas MS, Sau A, Greco E, O'Gorman N, Plasencia W, Pereira S, Jani JC, Valino N, Del Mar Gil M, Maclagan K, Wright A, Wright D, Nicolaides KH. Rehal A, et al. Am J Obstet Gynecol. 2021 Jan;224(1):86.e1-86.e19. doi: 10.1016/j.ajog.2020.06.050. Epub 2020 Jun 26. Am J Obstet Gynecol. 2021. PMID: 32598909 Free article. Clinical Trial.
Such apparent lack of effectiveness of progesterone in twins may be due to inadequate dosage or treatment that is started too late in pregnancy. ...A post hoc analysis using mixed-effects Cox regression was used for further exploration of the effect of progesterone
Such apparent lack of effectiveness of progesterone in twins may be due to inadequate dosage or treatment that is started too late in …
A clinical trial of progesterone for severe traumatic brain injury.
Skolnick BE, Maas AI, Narayan RK, van der Hoop RG, MacAllister T, Ward JD, Nelson NR, Stocchetti N; SYNAPSE Trial Investigators. Skolnick BE, et al. N Engl J Med. 2014 Dec 25;371(26):2467-76. doi: 10.1056/NEJMoa1411090. Epub 2014 Dec 10. N Engl J Med. 2014. PMID: 25493978 Free article. Clinical Trial.
BACKGROUND: Progesterone has been associated with robust positive effects in animal models of traumatic brain injury (TBI) and with clinical benefits in two phase 2 randomized, controlled trials. ...No relevant safety differences were noted between progesterone and …
BACKGROUND: Progesterone has been associated with robust positive effects in animal models of traumatic brain injury (TBI) and with c …
Effects of acute estradiol and progesterone on perimenstrual exacerbation of suicidal ideation and related symptoms: a crossover randomized controlled trial.
Eisenlohr-Moul TA, Bowers SM, Prinstein MJ, Schmalenberger KM, Walsh EC, Young SL, Rubinow DR, Girdler SS. Eisenlohr-Moul TA, et al. Transl Psychiatry. 2022 Dec 30;12(1):528. doi: 10.1038/s41398-022-02294-1. Transl Psychiatry. 2022. PMID: 36585408 Free PMC article. Clinical Trial.
Female suicide attempts peak peri-menstrually-around the onset of menses-when the ovarian steroids estradiol (E2) and progesterone (P4) fall rapidly. Given preclinical evidence that withdrawal from either E2 or P4 can provoke behaviors consistent with elevated suicide risk …
Female suicide attempts peak peri-menstrually-around the onset of menses-when the ovarian steroids estradiol (E2) and progesterone (P …
6,976 results