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1961 1
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2007 32
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2009 41
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2012 45
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2,044 results

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Page 1
Propafenone overdose.
Kerns W 2nd, English B, Ford M. Kerns W 2nd, et al. Ann Emerg Med. 1994 Jul;24(1):98-103. doi: 10.1016/s0196-0644(94)70168-7. Ann Emerg Med. 1994. PMID: 8010557 Review.
Propafenone is an infrequently used class IC antiarrhythmic drug. We report our experience with a patient who overdosed with propafenone and developed coma, seizures, bradycardia, hypotension, and conduction delay. The clinical manifestations and management of this …
Propafenone is an infrequently used class IC antiarrhythmic drug. We report our experience with a patient who overdosed with propa …
Revisiting propafenone toxicity.
Alsaad AA, Ortiz Gonzalez Y, Austin CO, Kusumoto F. Alsaad AA, et al. BMJ Case Rep. 2017 Apr 26;2017:bcr2017219270. doi: 10.1136/bcr-2017-219270. BMJ Case Rep. 2017. PMID: 28446489 Free PMC article.
Propafenone is a Vaughan Williams class 1c antiarrhythmic medication widely used for treatment of arrhythmias. ...Herein, we discuss an unusual adverse reaction to propafenone in a patient who presented with symptomatic bradycardia and hypotension. The aim of this a …
Propafenone is a Vaughan Williams class 1c antiarrhythmic medication widely used for treatment of arrhythmias. ...Herein, we discuss …
Propafenone.
Veale D, McComb JM, Gibson GJ. Veale D, et al. Lancet. 1990 Apr 21;335(8695):979. doi: 10.1016/0140-6736(90)91048-f. Lancet. 1990. PMID: 1970054 No abstract available.
Propafenone interacts stereoselectively with beta 1- and beta 2-adrenergic receptors.
Burnett DM, Gal J, Zahniser NR, Nies AS. Burnett DM, et al. J Cardiovasc Pharmacol. 1988;12(5):615-9. doi: 10.1097/00005344-198811000-00017. J Cardiovasc Pharmacol. 1988. PMID: 2468063
In contrast, competition curves for (+)-propafenone in the same tissues were more complex and revealed two binding sites with affinities 10- to 75-fold less potent than those for (-)-propafenone. Moreover, the (+)-propafenone was found by high performance liq …
In contrast, competition curves for (+)-propafenone in the same tissues were more complex and revealed two binding sites with affinit …
Propafenone-theophylline interaction.
Spinler SA, Gammaitoni A, Charland SL, Hurwitz J. Spinler SA, et al. Pharmacotherapy. 1993 Jan-Feb;13(1):68-71. Pharmacotherapy. 1993. PMID: 8437970
Both propafenone and theophylline are hepatically metabolized by the cytochrome P-450 enzyme system. The decrease in theophylline clearance of 25% to 69% in this patient may be due to competitive metabolism resulting in enzyme inhibition and increased theophylline concentr …
Both propafenone and theophylline are hepatically metabolized by the cytochrome P-450 enzyme system. The decrease in theophylline cle …
The role of genetically determined polymorphic drug metabolism in the beta-blockade produced by propafenone.
Lee JT, Kroemer HK, Silberstein DJ, Funck-Brentano C, Lineberry MD, Wood AJ, Roden DM, Woosley RL. Lee JT, et al. N Engl J Med. 1990 Jun 21;322(25):1764-8. doi: 10.1056/NEJM199006213222502. N Engl J Med. 1990. PMID: 1971708 Free article. Clinical Trial.
Propranolol and the sodium-channel-blocking antiarrhythmic agent propafenone share structural features. Although propafenone's beta-blocking actions are readily demonstrable in vitro, clinically significant beta-blockade occurs inconsistently in vivo. ...We conclude …
Propranolol and the sodium-channel-blocking antiarrhythmic agent propafenone share structural features. Although propafenone's …
Diprafenone.
[No authors listed] [No authors listed] Drugs R D. 1999 Apr;1(4):301-3. doi: 10.2165/00126839-199901040-00004. Drugs R D. 1999. PMID: 10566049 No abstract available.
Propafenone-induced psoriasis.
Palleschi GM, Bellandi S, Torchia D. Palleschi GM, et al. Clin Exp Dermatol. 2008 Mar;33(2):209-10. doi: 10.1111/j.1365-2230.2007.02671.x. Clin Exp Dermatol. 2008. PMID: 18257839 No abstract available.
Optimization of propafenone analogues as antimalarial leads.
Lowes DJ, Guiguemde WA, Connelly MC, Zhu F, Sigal MS, Clark JA, Lemoff AS, Derisi JL, Wilson EB, Guy RK. Lowes DJ, et al. J Med Chem. 2011 Nov 10;54(21):7477-85. doi: 10.1021/jm2005546. Epub 2011 Oct 10. J Med Chem. 2011. PMID: 21955244 Free PMC article.
Propafenone, a class Ic antiarrythmic drug, inhibits growth of cultured Plasmodium falciparum. ...A small array of propafenone analogues was designed and synthesized to address the cardiac ion channel and PK liabilities. ...
Propafenone, a class Ic antiarrythmic drug, inhibits growth of cultured Plasmodium falciparum. ...A small array of propafenone …
Propafenone-induced peripheral neuropathy.
Galasso PJ, Stanton MS, Vogel H. Galasso PJ, et al. Mayo Clin Proc. 1995 May;70(5):469-72. doi: 10.4065/70.5.469. Mayo Clin Proc. 1995. PMID: 7731257
Propafenone hydrochloride, a class IC antiarrhythmic drug, is used in the treatment of ventricular and supraventricular arrhythmias. ...To our knowledge, peripheral neuropathy has not previously been reported to occur with use of propafenone. In this patient, pro …
Propafenone hydrochloride, a class IC antiarrhythmic drug, is used in the treatment of ventricular and supraventricular arrhythmias. …
2,044 results