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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1952 7
1953 3
1954 11
1955 3
1956 27
1957 50
1958 20
1959 21
1960 13
1961 17
1962 30
1963 52
1964 60
1965 24
1966 21
1967 46
1968 52
1969 32
1970 47
1971 29
1972 29
1973 39
1974 47
1975 33
1976 29
1977 28
1978 24
1979 32
1980 28
1981 31
1982 37
1983 30
1984 38
1985 58
1986 47
1987 57
1988 50
1989 79
1990 68
1991 75
1992 74
1993 69
1994 87
1995 104
1996 124
1997 94
1998 121
1999 110
2000 102
2001 89
2002 137
2003 121
2004 135
2005 121
2006 129
2007 130
2008 157
2009 135
2010 169
2011 188
2012 197
2013 207
2014 200
2015 203
2016 215
2017 240
2018 228
2019 209
2020 252
2021 208
2022 142
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5,769 results
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Page 1
Pyrazinamide.
[No authors listed] [No authors listed] Tuberculosis (Edinb). 2008 Mar;88(2):141-4. doi: 10.1016/S1472-9792(08)70021-0. Tuberculosis (Edinb). 2008. PMID: 18486055 Review. No abstract available.
Metabolism and Hepatotoxicity of Pyrazinamide, an Antituberculosis Drug.
Hussain Z, Zhu J, Ma X. Hussain Z, et al. Drug Metab Dispos. 2021 Aug;49(8):679-682. doi: 10.1124/dmd.121.000389. Epub 2021 Jun 1. Drug Metab Dispos. 2021. PMID: 34074731 Free PMC article. Review.
Pyrazinamide (PZA) is an important component of a standard combination therapy against tuberculosis. ...
Pyrazinamide (PZA) is an important component of a standard combination therapy against tuberculosis. ...
Pyrazinamide.
Singh V, Choudhury P, Puri RK. Singh V, et al. Indian Pediatr. 1993 Feb;30(2):233-6. Indian Pediatr. 1993. PMID: 8375886 No abstract available.
Pyrazinamide resistance in rifampicin discordant tuberculosis.
Mvelase NR, Singh R, Swe Swe-Han K, Mlisana KP. Mvelase NR, et al. PLoS One. 2022 Sep 21;17(9):e0274688. doi: 10.1371/journal.pone.0274688. eCollection 2022. PLoS One. 2022. PMID: 36129921 Free PMC article.
We also compared susceptibility of pyrazinamide with that of isoniazid. RESULTS: Pyrazinamide resistance was found in 6/80 (7.5%) rifampicin discordant isolates. All pyrazinamide resistant isolates were also resistant to isoniazid and pyrazinamide resi …
We also compared susceptibility of pyrazinamide with that of isoniazid. RESULTS: Pyrazinamide resistance was found in 6/80 (7. …
Pyrazinamide resistance in Mycobacterium tuberculosis: Review and update.
Njire M, Tan Y, Mugweru J, Wang C, Guo J, Yew W, Tan S, Zhang T. Njire M, et al. Adv Med Sci. 2016 Mar;61(1):63-71. doi: 10.1016/j.advms.2015.09.007. Epub 2015 Oct 1. Adv Med Sci. 2016. PMID: 26521205 Review.
The global control and management of tuberculosis (TB) is faced with the formidable challenge of worsening scenarios of drug-resistant disease. Pyrazinamide (PZA) is an indispensable first-line drug used for the treatment of TB. ...
The global control and management of tuberculosis (TB) is faced with the formidable challenge of worsening scenarios of drug-resistant disea …
Pharmacological and Molecular Mechanisms Behind the Sterilizing Activity of Pyrazinamide.
Gopal P, Grüber G, Dartois V, Dick T. Gopal P, et al. Trends Pharmacol Sci. 2019 Dec;40(12):930-940. doi: 10.1016/j.tips.2019.10.005. Epub 2019 Nov 6. Trends Pharmacol Sci. 2019. PMID: 31704175 Free PMC article. Review.
Inclusion of pyrazinamide (PZA) in the tuberculosis (TB) drug regimen during the 1970s enabled a reduction in treatment duration from 12 to 6 months. ...
Inclusion of pyrazinamide (PZA) in the tuberculosis (TB) drug regimen during the 1970s enabled a reduction in treatment duration from …
The phase relationship between the pyrazinamide polymorphs α and γ.
Li K, Gbabode G, Barrio M, Tamarit JL, Vergé-Depré M, Robert B, Rietveld IB. Li K, et al. Int J Pharm. 2020 Apr 30;580:119230. doi: 10.1016/j.ijpharm.2020.119230. Epub 2020 Mar 19. Int J Pharm. 2020. PMID: 32199962
Pyrazinamide is an active pharmaceutical compound for the treatment of tuberculosis. ...However, despite the existence of a number of papers on the polymorphism of pyrazinamide, well-defined equilibrium conditions between the polymorphs appear to be lacking. ...
Pyrazinamide is an active pharmaceutical compound for the treatment of tuberculosis. ...However, despite the existence of a number of
Impact of the host environment on the antitubercular action of pyrazinamide.
Lamont EA, Baughn AD. Lamont EA, et al. EBioMedicine. 2019 Nov;49:374-380. doi: 10.1016/j.ebiom.2019.10.014. Epub 2019 Oct 25. EBioMedicine. 2019. PMID: 31669220 Free PMC article. Review.
Pyrazinamide remains the only drug in the tuberculosis pharmacopeia to drastically shorten first-line therapy from nine to six months. ...
Pyrazinamide remains the only drug in the tuberculosis pharmacopeia to drastically shorten first-line therapy from nine to six months
Targeted protein degradation in antibacterial drug discovery?
Gopal P, Dick T. Gopal P, et al. Prog Biophys Mol Biol. 2020 May;152:10-14. doi: 10.1016/j.pbiomolbio.2019.11.005. Epub 2019 Nov 16. Prog Biophys Mol Biol. 2020. PMID: 31738980 Free PMC article. Review.
Recently, we discovered that an antibacterial drug, the anti-tuberculosis antibiotic pyrazinamide, functions as a promotor of degradation of its bacterial target. ...Then, we describe how the first anti-bacterial target degradation promoter pyrazinamide triggers rem …
Recently, we discovered that an antibacterial drug, the anti-tuberculosis antibiotic pyrazinamide, functions as a promotor of degrada …
FFCASP: A Massively Parallel Crystal Structure Prediction Algorithm.
Demir S, Tekin A. Demir S, et al. J Chem Theory Comput. 2021 Apr 13;17(4):2586-2598. doi: 10.1021/acs.jctc.0c01197. Epub 2021 Apr 2. J Chem Theory Comput. 2021. PMID: 33798330
Three different molecular crystals, including diverse intermolecular interactions, namely, cytosine, coumarin, and pyrazinamide, have been selected to evaluate the performance of FFCASP. ...Two of the reported crystal structures of coumarin have been reproduced. Similarly, …
Three different molecular crystals, including diverse intermolecular interactions, namely, cytosine, coumarin, and pyrazinamide, have …
5,769 results