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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1951 1
1952 14
1953 41
1954 24
1955 11
1956 21
1957 25
1958 19
1959 16
1960 17
1961 13
1962 9
1963 36
1964 51
1965 42
1966 44
1967 44
1968 69
1969 63
1970 53
1971 66
1972 69
1973 73
1974 72
1975 62
1976 64
1977 58
1978 42
1979 54
1980 56
1981 78
1982 77
1983 71
1984 93
1985 111
1986 94
1987 106
1988 126
1989 127
1990 128
1991 120
1992 110
1993 135
1994 105
1995 125
1996 133
1997 135
1998 130
1999 115
2000 108
2001 120
2002 153
2003 150
2004 180
2005 193
2006 204
2007 237
2008 185
2009 180
2010 194
2011 216
2012 171
2013 183
2014 176
2015 172
2016 175
2017 167
2018 153
2019 144
2020 166
2021 183
2022 173
2023 170
2024 182
2025 208
2026 124

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7,718 results

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Page 1
Drug-resistant malaria.
[No authors listed] [No authors listed] Lancet. 1981 Nov 14;2(8255):1087-8. Lancet. 1981. PMID: 6118530 No abstract available.
Pyrimethamine poisoning.
Akinyanju O, Goddell JC, Ahmed I. Akinyanju O, et al. Br Med J. 1973 Oct 20;4(5885):147-8. doi: 10.1136/bmj.4.5885.147. Br Med J. 1973. PMID: 4543103 Free PMC article. No abstract available.
Pyrimethamine Inhibits Human Ovarian Cancer by Triggering Lethal Mitophagy via Activating the p38/JNK/ERK Pathway.
Linghu L, Zhou H, Zheng G, Yi T. Linghu L, et al. Oncol Res. 2025 Aug 28;33(9):2421-2434. doi: 10.32604/or.2025.063724. eCollection 2025. Oncol Res. 2025. PMID: 40918465 Free PMC article.
Furthermore, transcriptome analysis and immunohistochemical techniques were employed to detect the impact of pyrimethamine on ovarian cancer cells. RESULTS: Our results demonstrated that pyrimethamine induced ovarian cancer cell death through mitochondrial dysfuncti …
Furthermore, transcriptome analysis and immunohistochemical techniques were employed to detect the impact of pyrimethamine on ovarian …
Toxoplasmosis.
[No authors listed] [No authors listed] Med Lett Drugs Ther. 1968 Dec 27;10(26):107-8. Med Lett Drugs Ther. 1968. PMID: 5730153 No abstract available.
PYRIMETHAMINE.
[No authors listed] [No authors listed] J Am Med Assoc. 1956 Aug 4;161(14):1384-5. J Am Med Assoc. 1956. PMID: 13331808 No abstract available.
The multifaceted antineoplastic role of pyrimethamine against human malignancies.
Ramchandani S, Mohan CD, Mistry JR, Su Q, Naz I, Rangappa KS, Ahn KS. Ramchandani S, et al. IUBMB Life. 2022 Mar;74(3):198-212. doi: 10.1002/iub.2590. Epub 2022 Jan 5. IUBMB Life. 2022. PMID: 34921584 Free article. Review.
Moreover, pyrimethamine has been reported to work in synergy with other anticancer agents, such as temozolomide, to induce apoptosis of tumor cells. ...We have also discussed the pharmacokinetic profile and results of clinical trials obtained after pyrimethamine tre …
Moreover, pyrimethamine has been reported to work in synergy with other anticancer agents, such as temozolomide, to induce apoptosis …
Chemoprevention by pyrimethamine.
Saadat F, Khorramizadeh MR, Mirshafiey A. Saadat F, et al. Immunopharmacol Immunotoxicol. 2005;27(2):233-40. doi: 10.1081/iph-200067736. Immunopharmacol Immunotoxicol. 2005. PMID: 16114507
Pyrimethamine and methotrexate were used at concentrations of 0-8 microg/ml in triplicate and 2-fold dilutions. ...Our data suggest that pyrimethamine enables suppression of MMP-2 activity and induces apoptosis that could be assumed for chemoprevention therapy....
Pyrimethamine and methotrexate were used at concentrations of 0-8 microg/ml in triplicate and 2-fold dilutions. ...Our data suggest t …
Pyrimethamine in pregnancy.
Harpey JP. Harpey JP. Lancet. 1983 Nov 19;2(8360):1193. doi: 10.1016/s0140-6736(83)91237-0. Lancet. 1983. PMID: 6139544 No abstract available.
A new effective antiplasmodial compound: Nanoformulated pyrimethamine.
Pestehchian N, Vafaei MR, Nematolahy P, Varshosaz J, Yousefi HA, Bide VZ, Kalani H. Pestehchian N, et al. J Glob Antimicrob Resist. 2020 Mar;20:309-315. doi: 10.1016/j.jgar.2019.08.002. Epub 2019 Aug 9. J Glob Antimicrob Resist. 2020. PMID: 31404680 Free article.
METHODS: Pyrimethamine-loaded nanomicelles were prepared and their zeta potential, particle size and polydispersity index were measured. ...Three of the P. berghei-infected groups received treatment with either pyrimethamine-loaded nanomicelles (2 mg/kg), pyrimet …
METHODS: Pyrimethamine-loaded nanomicelles were prepared and their zeta potential, particle size and polydispersity index were measur …
7,718 results