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96 results

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Page 1
Targeted Delivery of Zinc Pyrithione to Skin Epithelia.
Mangion SE, Holmes AM, Roberts MS. Mangion SE, et al. Int J Mol Sci. 2021 Sep 8;22(18):9730. doi: 10.3390/ijms22189730. Int J Mol Sci. 2021. PMID: 34575891 Free PMC article. Review.
Anti-fungal activity of ZnPT depends on the cutaneous availability of bioactive monomeric molecular species, occurring upon particle dissolution. The success of ZnPT as a topical therapeutic is underscored by the way it balances treatment efficacy with formulation safety. …
Anti-fungal activity of ZnPT depends on the cutaneous availability of bioactive monomeric molecular species, occurring upon particle dissolu …
Optical Characterization of Zinc Pyrithione.
Sandiford L, Holmes AM, Mangion SE, Mohammed YH, Zvyagin AV, Roberts MS. Sandiford L, et al. Photochem Photobiol. 2019 Sep;95(5):1142-1150. doi: 10.1111/php.13100. Epub 2019 Apr 22. Photochem Photobiol. 2019. PMID: 30883774
Zinc pyrithione is ubiquitous in commercial products particularly antidandruff shampoos. For the efficacy of zinc pyrithione therapeutic cleansers to be assessed accurately, the distribution of particles on the scalp needs to be visualized. ...
Zinc pyrithione is ubiquitous in commercial products particularly antidandruff shampoos. For the efficacy of zinc pyrithione therapeutic …
Scalp application of antioxidants improves scalp condition and reduces hair shedding in a 24-week randomized, double-blind, placebo-controlled clinical trial.
Davis MG, Piliang MP, Bergfeld WF, Caterino TL, Fisher BK, Sacha JP, Carr GJ, Moulton LT, Whittenbarger DJ, Schwartz JR. Davis MG, et al. Int J Cosmet Sci. 2021 Nov;43 Suppl 1:S14-S25. doi: 10.1111/ics.12734. Int J Cosmet Sci. 2021. PMID: 34424558 Clinical Trial.
The functional ingredients were piroctone olamine, zinc pyrithione, zinc carbonate, niacinamide, panthenol and caffeine. At baseline and after 8, 16 and 24 weeks of product use, several measurements were taken: hair shedding, total hair count (by phototrichogram), h …
The functional ingredients were piroctone olamine, zinc pyrithione, zinc carbonate, niacinamide, panthenol and caffeine. At ba …
Zinc pyrithione ameliorates colitis in mice by interacting on intestinal epithelial TRPA1 and TRPV4 channels.
Zhang M, Chen X, Zhang L, Li J, Sun C, Zhou G, Wan H, Lu W, Dong H. Zhang M, et al. Life Sci. 2024 Dec 1;358:123090. doi: 10.1016/j.lfs.2024.123090. Epub 2024 Oct 9. Life Sci. 2024. PMID: 39384148
Our aims were to investigate the effects of ZPT on transient receptor potential (TRP) channels and Ca(2+) signaling in intestinal epithelial cells (IECs) and its therapeutic potential for colitis. MAIN METHODS: Digital Ca(2+) imaging and patch-clamp electrophysiology were …
Our aims were to investigate the effects of ZPT on transient receptor potential (TRP) channels and Ca(2+) signaling in intestinal epithelial …
Seborrhoeic dermatitis.
Ijaz N, Fitzgerald D. Ijaz N, et al. Br J Hosp Med (Lond). 2017 Jun 2;78(6):C88-C91. doi: 10.12968/hmed.2017.78.6.C88. Br J Hosp Med (Lond). 2017. PMID: 28614013 No abstract available.
Zinc pyrithione is a potent inhibitor of PLPro and cathepsin L enzymes with ex vivo inhibition of SARS-CoV-2 entry and replication.
Kladnik J, Dolinar A, Kljun J, Perea D, Grau-Expósito J, Genescà M, Novinec M, Buzon MJ, Turel I. Kladnik J, et al. J Enzyme Inhib Med Chem. 2022 Dec;37(1):2158-2168. doi: 10.1080/14756366.2022.2108417. J Enzyme Inhib Med Chem. 2022. PMID: 35943189 Free PMC article.
Safe, effective, and preferably oral at-home therapeutics for COVID-19 are needed and as such zinc pyrithione, which is also commercially available, could be considered as a potential therapeutic agent against SARS-CoV-2....
Safe, effective, and preferably oral at-home therapeutics for COVID-19 are needed and as such zinc pyrithione, which is also commercially av …
Zinc pyrithione activates the volume-regulated anion channel through an antioxidant-sensitive mechanism.
Figueroa EE, Denton JS. Figueroa EE, et al. Am J Physiol Cell Physiol. 2021 Jun 1;320(6):C1088-C1098. doi: 10.1152/ajpcell.00070.2021. Epub 2021 Apr 7. Am J Physiol Cell Physiol. 2021. PMID: 33826406 Free PMC article.
Leucine-rich repeat-containing 8 (LRRC8) volume-regulated anion channels (VRACs) play important physiological roles in diverse cell types and may represent therapeutic targets for various diseases. To date, however, the pharmacological tools for evaluating the druggability …
Leucine-rich repeat-containing 8 (LRRC8) volume-regulated anion channels (VRACs) play important physiological roles in diverse cell types an …
Zinc pyrithione (Zinc Omadine) allergy.
Brandrup F, Menné T. Brandrup F, et al. Contact Dermatitis. 1985 Jan;12(1):50. doi: 10.1111/j.1600-0536.1985.tb01041.x. Contact Dermatitis. 1985. PMID: 3979043 No abstract available.
96 results