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164 results

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Page 1
Targeted Delivery of Zinc Pyrithione to Skin Epithelia.
Mangion SE, Holmes AM, Roberts MS. Mangion SE, et al. Int J Mol Sci. 2021 Sep 8;22(18):9730. doi: 10.3390/ijms22189730. Int J Mol Sci. 2021. PMID: 34575891 Free PMC article. Review.
Zinc pyrithione (ZnPT) is an anti-fungal drug delivered as a microparticle to skin epithelia. ...Toxicologic investigations have focused on understanding the risk of local and systemic adverse effects following exposure from percutaneous penetration. Future r …
Zinc pyrithione (ZnPT) is an anti-fungal drug delivered as a microparticle to skin epithelia. ...Toxicologic investigations have focu …
Zinc pyrithione in alcohol-based products for skin antisepsis: persistence of antimicrobial effects.
Guthery E, Seal LA, Anderson EL. Guthery E, et al. Am J Infect Control. 2005 Feb;33(1):15-22. doi: 10.1016/j.ajic.2004.07.012. Am J Infect Control. 2005. PMID: 15685130 Free PMC article. Review.
Therefore, alcohol-based products must have a preservative agent such as iodine/iodophor compounds, chlorhexidine gluconate, or zinc pyrithione, to extend its antimicrobial effects. Iodine, iodophors, and chlorhexidine gluconate are well-characterized antimicrobials …
Therefore, alcohol-based products must have a preservative agent such as iodine/iodophor compounds, chlorhexidine gluconate, or zinc pyri …
Environmental occurrence, biological effects, and health implications of zinc pyrithione: A review.
Wu X, Jeong CB, Huang W, Ip JC, Guo J, Lai KP, Liu W, Mo J. Wu X, et al. Mar Pollut Bull. 2024 Jun;203:116466. doi: 10.1016/j.marpolbul.2024.116466. Epub 2024 May 6. Mar Pollut Bull. 2024. PMID: 38713926 Review.
Due to the detrimental effects on aquatic organisms and ecosystem, tributyltin as a antifouling agent have been banned worldwide since 1990s. As a replacement for tributyltin, zinc pyrithione (ZnPT) has emerged as a new environmentally friendly antifouling agent. Ho …
Due to the detrimental effects on aquatic organisms and ecosystem, tributyltin as a antifouling agent have been banned worldwide sinc …
Copper pyrithione and zinc pyrithione induce cytotoxicity and neurotoxicity in neuronal/astrocytic co-cultured cells via oxidative stress.
Oh HN, Kim WK. Oh HN, et al. Sci Rep. 2023 Dec 27;13(1):23060. doi: 10.1038/s41598-023-49740-8. Sci Rep. 2023. PMID: 38155222 Free PMC article.
Previous studies on copper pyrithione (CPT) and zinc pyrithione (ZPT) as antifouling agents have mainly focused on marine organisms. ...Notably, N-acetylcysteine treatment showed neuroprotective effects against CPT- and ZPT-mediated toxicity. We concluded tha …
Previous studies on copper pyrithione (CPT) and zinc pyrithione (ZPT) as antifouling agents have mainly focused on marine orga …
Nanomolar concentrations of zinc pyrithione increase cell susceptibility to oxidative stress induced by hydrogen peroxide in rat thymocytes.
Oyama TM, Saito M, Yonezawa T, Okano Y, Oyama Y. Oyama TM, et al. Chemosphere. 2012 Jun;87(11):1316-22. doi: 10.1016/j.chemosphere.2012.01.052. Epub 2012 Feb 21. Chemosphere. 2012. PMID: 22356860
Zinc pyrithione is used as an antifouling agent. However, the environmental impacts of zinc pyrithione have recently been of concern. ...The cytotoxicity of zinc pyrithione was not observed when the cells were incubated with 3 muM zinc pyrithione for 3 …
Zinc pyrithione is used as an antifouling agent. However, the environmental impacts of zinc pyrithione have recently been of c …
Zinc pyrithione exposure compromises oocyte maturation through involving in spindle assembly and zinc accumulation.
Wang YS, Yang SJ, Ahmad MJ, Ding ZM, Duan ZQ, Chen YW, Liu M, Liang AX, Hua GH, Huo LJ. Wang YS, et al. Ecotoxicol Environ Saf. 2022 Apr 1;234:113393. doi: 10.1016/j.ecoenv.2022.113393. Epub 2022 Mar 9. Ecotoxicol Environ Saf. 2022. PMID: 35278989 Free article.
Zinc Pyrithione (ZPT), a Food and Drug Administration (FDA) approved chemical, is widely used for topical antimicrobials and cosmetic consumer products, including anti-dandruff shampoos. ...Herein, we investigated the adverse impact of ZPT on mouse oocyte maturation …
Zinc Pyrithione (ZPT), a Food and Drug Administration (FDA) approved chemical, is widely used for topical antimicrobials and cosmetic …
SSA-ZP on Scalp Seborrheic Dermatitis: Regulating Sebum Levels and Scalp Barrier.
Wang Q, Liu Y, Ye C, Shen J, Lin J, Du Y, Li L, Huang X, Zheng Y. Wang Q, et al. J Cosmet Dermatol. 2025 Jan;24(1):e16617. doi: 10.1111/jocd.16617. Epub 2024 Oct 28. J Cosmet Dermatol. 2025. PMID: 39466953 Free PMC article.
Supramolecular salicylic acid has the keratolytic and anti-inflammatory properties, and zinc pyrithione is an antifungal drug delivered as a microparticle to skin epithelia. OBJECTIVE: This study aimed to assess the efficacy and safety of 2% supramolecular salicylic acid ( …
Supramolecular salicylic acid has the keratolytic and anti-inflammatory properties, and zinc pyrithione is an antifungal drug deliver …
Comparison of the effects of sublethal concentrations of biofoulants, copper pyrithione and zinc pyrithione on a marine mysid - A multigenerational study.
Lee S, Haque MN, Lee DH, Rhee JS. Lee S, et al. Comp Biochem Physiol C Toxicol Pharmacol. 2023 Sep;271:109694. doi: 10.1016/j.cbpc.2023.109694. Epub 2023 Jul 1. Comp Biochem Physiol C Toxicol Pharmacol. 2023. PMID: 37394131
To determine the effect of copper pyrithione (CuPT) and zinc pyrithione (ZnPT), a set of acute (96 h-LC50) and chronic endpoints was studied in the marine mysid, Neomysis awatschensis. ...These results indicate that CuPT has a higher toxicity than ZnPT and even subl …
To determine the effect of copper pyrithione (CuPT) and zinc pyrithione (ZnPT), a set of acute (96 h-LC50) and chronic endpoin …
Ecotoxicological effect of zinc pyrithione in the freshwater fish Gambusia holbrooki.
Nunes B, Braga MR, Campos JC, Gomes R, Ramos AS, Antunes SC, Correia AT. Nunes B, et al. Ecotoxicology. 2015 Nov;24(9):1896-905. doi: 10.1007/s10646-015-1525-6. Epub 2015 Aug 23. Ecotoxicology. 2015. PMID: 26298705
Previously reported data has shown the presence of this substance in the aquatic compartment, a factor contributing to the potential exertion of toxic effects, and there is also evidence that photodegradation products of zinc pyrithione were involved in neurotoxic …
Previously reported data has shown the presence of this substance in the aquatic compartment, a factor contributing to the potential exertio …
Zinc pyrithione (ZPT) -induced embryonic toxicogenomic responses reveal involvement of oxidative damage, apoptosis, endoplasmic reticulum (ER) stress and autophagy.
Zhao Y, Wang H, Duah PA, Retyunskiy V, Liu Y, Chen G. Zhao Y, et al. Aquat Toxicol. 2022 Jul;248:106195. doi: 10.1016/j.aquatox.2022.106195. Epub 2022 May 13. Aquat Toxicol. 2022. PMID: 35594629
Zinc pyrithione (ZPT) is a frequently used organometallic biocide, carrying potentially adverse consequences to multiple species in the environment. ...The present study was designed to evaluate the effects and possible mechanisms of ZPT-induced embryonic tox …
Zinc pyrithione (ZPT) is a frequently used organometallic biocide, carrying potentially adverse consequences to multiple speci …
164 results