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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1962 4
1963 1
1964 1
1974 2
1975 16
1976 21
1977 45
1978 23
1979 25
1980 29
1981 26
1982 31
1983 39
1984 42
1985 58
1986 64
1987 97
1988 90
1989 80
1990 106
1991 73
1992 69
1993 83
1994 85
1995 98
1996 103
1997 99
1998 143
1999 237
2000 299
2001 340
2002 450
2003 569
2004 671
2005 739
2006 721
2007 725
2008 745
2009 846
2010 922
2011 1112
2012 1145
2013 1224
2014 1379
2015 1266
2016 1114
2017 912
2018 750
2019 570
2020 652
2021 515
2022 347
2023 33
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18,005 results
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Page 1
What future for ribavirin?
Shiffman ML. Shiffman ML. Liver Int. 2009 Jan;29 Suppl 1:68-73. doi: 10.1111/j.1478-3231.2008.01936.x. Liver Int. 2009. PMID: 19207968 Review.
The optimal therapy for patients with the chronic hepatitis C virus (HCV) is a combination of peginterferon and ribavirin. Treating HCV without ribavirin or prematurely discontinuing, frequently missing doses of ribavirin is associated with a significant decl …
The optimal therapy for patients with the chronic hepatitis C virus (HCV) is a combination of peginterferon and ribavirin. Treating H …
Ribavirin analogs.
Shields WW, Pockros PJ. Shields WW, et al. Clin Liver Dis. 2009 Aug;13(3):419-27. doi: 10.1016/j.cld.2009.05.006. Clin Liver Dis. 2009. PMID: 19628158
Ribavirin has significant dose-limiting toxicities, the most important of which is hemolytic anemia. Taribavirin is a ribavirin pro-drug, which targets the liver and has less incidence of anemia, and it may be a promising alternative to ribavirin in the futur …
Ribavirin has significant dose-limiting toxicities, the most important of which is hemolytic anemia. Taribavirin is a ribavirin …
Ribavirin pharmacokinetics.
Connor J. Connor J. Pediatr Infect Dis J. 1990 Sep;9(9 Suppl):S91-2. doi: 10.1097/00006454-199009001-00009. Pediatr Infect Dis J. 1990. PMID: 2235214 Review. No abstract available.
When will resistance be futile?
Borden KL. Borden KL. Cancer Res. 2014 Dec 15;74(24):7175-80. doi: 10.1158/0008-5472.CAN-14-2607. Epub 2014 Dec 4. Cancer Res. 2014. PMID: 25477336 Free PMC article. Review.
This form was discovered while developing means to target a specific oncogene, the eukaryotic translation initiation factor 4E (eIF4E), with its inhibitor ribavirin. In two clinical studies, ribavirin treatment led to substantial clinical responses, but all respondi …
This form was discovered while developing means to target a specific oncogene, the eukaryotic translation initiation factor 4E (eIF4E), with …
The clinical pharmacology of ribavirin.
Glue P. Glue P. Semin Liver Dis. 1999;19 Suppl 1:17-24. Semin Liver Dis. 1999. PMID: 10349689 Review.
Apparent volume of distribution is extensive (approximately 2,000 L) due to ribavirin's distribution into nonplasma (cellular) compartments, which occurs via es-nucleoside transporters. ...The pharmacokinetic properties of ribavirin in special populations, th …
Apparent volume of distribution is extensive (approximately 2,000 L) due to ribavirin's distribution into nonplasma (cellular) …
The Use of Ribavirin as an Anticancer Therapeutic: Will It Go Viral?
Casaos J, Gorelick NL, Huq S, Choi J, Xia Y, Serra R, Felder R, Lott T, Kast RE, Suk I, Brem H, Tyler B, Skuli N. Casaos J, et al. Mol Cancer Ther. 2019 Jul;18(7):1185-1194. doi: 10.1158/1535-7163.MCT-18-0666. Mol Cancer Ther. 2019. PMID: 31263027 Review.
In this review, we summarize the role of ribavirin as an antiviral medication and focus our attention on its recent use as an antitumoral agent. ...Converging evidence suggests that ribavirin represents a promising addition to a generation of newly repurposed safe a …
In this review, we summarize the role of ribavirin as an antiviral medication and focus our attention on its recent use as an antitum …
Metabolism and antiviral activity of ribavirin.
Parker WB. Parker WB. Virus Res. 2005 Feb;107(2):165-71. doi: 10.1016/j.virusres.2004.11.006. Virus Res. 2005. PMID: 15649562 Review.
Thirty years after its synthesis, the mechanism of action of ribavirin is still not completely understood. Although much is known about the metabolism and biochemical effects of ribavirin in human cells, there is still much to be learned about the precise mechanism …
Thirty years after its synthesis, the mechanism of action of ribavirin is still not completely understood. Although much is known abo …
Ribavirin Does Not Enhance Hepatitis B Virus Nucleotide Antiviral Activity: A Pilot Study.
Keeshan A, Coffin C, Vachon A, Patel N, Fung S, Mortimer L, Crawley A, Ma M, Osiowy C, Cooper C. Keeshan A, et al. Clin Invest Med. 2022 Dec 31;45(4):E11-15. doi: 10.25011/cim.v45i4.39274. Clin Invest Med. 2022. PMID: 36586101 Clinical Trial.
The use of immune-modulators combined with HBV antivirals is a promising therapeutic strategy to achieve these goals. Based on ribavirin (RBV) monotherapy data, we hypothesized that RBV could improve virological responses when used in combination with tenofovir. ...
The use of immune-modulators combined with HBV antivirals is a promising therapeutic strategy to achieve these goals. Based on ribavirin …
Ribavirin's antiviral mechanism of action: lethal mutagenesis?
Crotty S, Cameron C, Andino R. Crotty S, et al. J Mol Med (Berl). 2002 Feb;80(2):86-95. doi: 10.1007/s00109-001-0308-0. Epub 2001 Dec 4. J Mol Med (Berl). 2002. PMID: 11907645 Review.
Ribavirin, an antiviral drug discovered in 1972, is interesting and important for three reasons: (a) it exhibits antiviral activity against a broad range of RNA viruses; (b) it is currently used clinically to treat hepatitis C virus infections, respiratory syncytial virus …
Ribavirin, an antiviral drug discovered in 1972, is interesting and important for three reasons: (a) it exhibits antiviral activity a …
Ribavirin: a clinical overview.
Fernandez H, Banks G, Smith R. Fernandez H, et al. Eur J Epidemiol. 1986 Mar;2(1):1-14. doi: 10.1007/BF00152711. Eur J Epidemiol. 1986. PMID: 3021519 Review.
Special note is taken of ribavirin's clinical benefit in treating severe and life-threatening infections caused by the Lassa fever virus and the significant improvement over either the use of immune plasma or supportive therapy alone. ...Additional studies demonstra …
Special note is taken of ribavirin's clinical benefit in treating severe and life-threatening infections caused by the Lassa f …
18,005 results
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