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Year Number of Results
1989 1
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2,957 results

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Page 1
Evaluating the efficacy and safety of perianal injection of liposomal ropivacaine HR18034 for postoperative analgesia following hemorrhoidectomy: A multicenter, randomized, double-blind, controlled phase II clinical trial.
Li Q, Xu S, Ou Y, Zhou L, Huang F, Jiang W, Xie H, Zou X, Gao J, Jin S, Zhou H, Huang Y, Pan Z, Liu J, Wang G, Li X, Sun C, Zhao L, Li L, Liu Q, Duan K, Wang S. Li Q, et al. J Clin Anesth. 2024 Oct;97:111524. doi: 10.1016/j.jclinane.2024.111524. Epub 2024 Jun 27. J Clin Anesth. 2024. PMID: 38941870 Clinical Trial.
STUDY OBJECTIVE: HR18034, composed of the ropivacaine encapsulated in multi-lamellar, concentric circular structure liposomes as the major component and a small amount of free ropivacaine, has performed well in animal experiments and phase I clinical trials. ...Ther …
STUDY OBJECTIVE: HR18034, composed of the ropivacaine encapsulated in multi-lamellar, concentric circular structure liposomes as the …
A randomized trial: The safety, pharmacokinetics and preliminary pharmacodynamics of ropivacaine oil delivery depot in healthy subjects.
Lu WD, Zhao DL, Wang MX, Jiao YQ, Chi P, Zhang M, Ma B, Dong JP, Zhang HB, Yang Y, Tian Y, Hui MQ, Yang B, Cao YX. Lu WD, et al. PLoS One. 2023 Sep 19;18(9):e0291793. doi: 10.1371/journal.pone.0291793. eCollection 2023. PLoS One. 2023. PMID: 37725618 Free PMC article. Clinical Trial.
INTRODUCTION: Ropivacaine oil delivery depot (RODD) can slowly release ropivacaine and block nerves for a long timejavascript:;. ...Other adverse reactions disappeared after 7 days. The curve of ropivacaine concentration-time in plasma presented a bimodal pro …
INTRODUCTION: Ropivacaine oil delivery depot (RODD) can slowly release ropivacaine and block nerves for a long timejavascript: …
The Effects of Intraperitoneal Dexmedetomidine in Comparison with Ropivacaine in Postoperative Pain After Laparoscopic Sleeve Gastrectomy: A Double-Blind, Randomized, Placebo-Controlled, Clinical Trial.
Neishaboury M, Shokri S, Kianpour P, Farhadi K, Najjari K, Sharifnia H, MohammadYousef R, Khajavi M. Neishaboury M, et al. Obes Surg. 2025 Jun;35(6):2150-2159. doi: 10.1007/s11695-025-07871-z. Epub 2025 Apr 26. Obes Surg. 2025. PMID: 40281250 Clinical Trial.
We evaluated the effectiveness of ropivacaine alone and in combination with dexmedetomidine in improving outcomes after sleeve gastrectomy surgery. ...The participants were randomly divided into three groups: treated with ropivacaine alone (group A), ropivacaine …
We evaluated the effectiveness of ropivacaine alone and in combination with dexmedetomidine in improving outcomes after sleeve gastre …
Noninferiority of 0.25% versus 0.375% Ropivacaine in Popliteal Sciatic and Saphenous Nerve Blocks for Analgesia After Foot and Ankle Surgery: A Randomized Self-Paired Noninferiority Trial.
Wu L, Xi C, Lei G, Li H, Yin Y, Wan M, Wu H, Wang Y, Hu C, Wang G. Wu L, et al. Drug Des Devel Ther. 2025 May 19;19:4093-4104. doi: 10.2147/DDDT.S508528. eCollection 2025. Drug Des Devel Ther. 2025. PMID: 40416797 Free PMC article. Clinical Trial.

Compared with 0.375% ropivacaine, 0.25% ropivacaine resulted in a lower incidence of motor block at 0, 2, 6 and 12 hours postoperatively (P < 0.05). ...Moreover, 0.25% ropivacaine reduced the incidence of motor block. Therefore, we recommend 0.25% ropiv

…
Compared with 0.375% ropivacaine, 0.25% ropivacaine resulted in a lower incidence of motor block at 0, 2, 6 and 12 hours posto …
Serratus Anterior Plane Block with Methylene Blue and Ropivacaine for Analgesia in Prosthetic Breast Augmentation: A Randomized Controlled Trial.
Zhang T, Feng W, Li H, Lin Y, Mu D. Zhang T, et al. Plast Reconstr Surg. 2026 Mar 1;157(3):452-462. doi: 10.1097/PRS.0000000000012344. Epub 2025 Jul 29. Plast Reconstr Surg. 2026. PMID: 40737384 Clinical Trial.
However, routine analgesia is not always effective for all patients. Duration of regional block with ropivacaine is also limited. The objective of this study was to evaluate whether the combination of methylene blue and ropivacaine by means of serratus anterior plan …
However, routine analgesia is not always effective for all patients. Duration of regional block with ropivacaine is also limited. The …
A clinical and pharmacokinetic comparison of ropivacaine and bupivacaine in axillary plexus block.
Vainionpää VA, Haavisto ET, Huha TM, Korpi KJ, Nuutinen LS, Hollmén AI, Jozwiak HM, Magnusson AA. Vainionpää VA, et al. Anesth Analg. 1995 Sep;81(3):534-8. doi: 10.1097/00000539-199509000-00019. Anesth Analg. 1995. PMID: 7653818 Clinical Trial.
The clinical and pharmacokinetic properties of ropivacaine and bupivacaine, both 5 mg/mL, used in axillary plexus block were compared in 60 patients in this randomized, double-blind, parallel-group study. ...The median terminal half-lives (t1/2) were 7.1 h and 11.5 h in th …
The clinical and pharmacokinetic properties of ropivacaine and bupivacaine, both 5 mg/mL, used in axillary plexus block were compared …
The clinical efficacy and pharmacokinetics of intraperitoneal ropivacaine for laparoscopic cholecystectomy.
Labaille T, Mazoit JX, Paqueron X, Franco D, Benhamou D. Labaille T, et al. Anesth Analg. 2002 Jan;94(1):100-5, table of contents. doi: 10.1097/00000539-200201000-00019. Anesth Analg. 2002. PMID: 11772809 Clinical Trial.
Thirty-seven ASA physical status I or II patients received in double-blinded fashion 20 mL of 0.9% saline solution (placebo), ropivacaine 0.25% (Rop 0.25%), or ropivacaine 0.75% (Rop 0.75%) immediately after trocar placement and at the end of surgery. ...IMPLICATION …
Thirty-seven ASA physical status I or II patients received in double-blinded fashion 20 mL of 0.9% saline solution (placebo), ropivacaine …
Intraperitoneal ropivacaine and early postoperative pain and postsurgical outcomes after laparoscopic herniorrhaphy in toddlers: a randomized clinical trial.
Tian X, Yang P, Su T, Yu J, Zhao S, Xiang G, Yu D, Zhang W, Manyande A, Gao F, Tian Y, Yang H. Tian X, et al. Paediatr Anaesth. 2016 Sep;26(9):891-8. doi: 10.1111/pan.12953. Epub 2016 Jun 27. Paediatr Anaesth. 2016. PMID: 27346807 Clinical Trial.
Compared with the control group, time to flatus in ropivacaine group was also much shorter [21.1 h vs 16.7 h, P = 0.04, difference in mean (95% CI) is 4.4 (1.49-7.28)], and the time to first stool after surgery was earlier in the ropivacaine group [30.7 h vs 25.6 h, …
Compared with the control group, time to flatus in ropivacaine group was also much shorter [21.1 h vs 16.7 h, P = 0.04, difference in …
Comparative clinical trial of intracameral ropivacaine vs. lignocaine in subjects undergoing phacoemulsification under augmented topical anesthesia.
Sharma AK, Singh S, Hansraj S, Gupta AK, Agrawal S, Katiyar V, Gupta SK. Sharma AK, et al. Indian J Ophthalmol. 2020 Apr;68(4):577-582. doi: 10.4103/ijo.IJO_1388_19. Indian J Ophthalmol. 2020. PMID: 32174572 Free PMC article. Clinical Trial.
PURPOSE: To compare intracameral Ropivacaine to Lignocaine during phacoemulsification under augmented topical anesthesia, in terms of efficacy and safety. ...However, intracameral Ropivacaine is superior to Lignocaine with regards to corneal endothelial cell safety, …
PURPOSE: To compare intracameral Ropivacaine to Lignocaine during phacoemulsification under augmented topical anesthesia, in terms of …
Comparative clinical trial of topical anaesthetic agents for cataract surgery with phacoemulsification: lidocaine 2% drops, levobupivacaine 0.75% drops, and ropivacaine 1% drops.
Borazan M, Karalezli A, Akova YA, Algan C, Oto S. Borazan M, et al. Eye (Lond). 2008 Mar;22(3):425-9. doi: 10.1038/sj.eye.6702973. Epub 2007 Sep 7. Eye (Lond). 2008. PMID: 17828144 Clinical Trial.
Surgeon and patient satisfaction scores were significantly better in the levobupivacaine and ropivacaine groups than in the lidocaine group (P<0.01). CONCLUSIONS: Topical anaesthesia with levobupivacaine and ropivacaine were safe, feasible and more effective than …
Surgeon and patient satisfaction scores were significantly better in the levobupivacaine and ropivacaine groups than in the lidocaine …
2,957 results