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191 results

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Page 1
American Gastroenterological Association-American College of Gastroenterology Clinical Practice Guideline: Pharmacological Management of Chronic Idiopathic Constipation.
Chang L, Chey WD, Imdad A, Almario CV, Bharucha AE, Diem S, Greer KB, Hanson B, Harris LA, Ko C, Murad MH, Patel A, Shah ED, Lembo AJ, Sultan S. Chang L, et al. Am J Gastroenterol. 2023 Jun 1;118(6):936-954. doi: 10.14309/ajg.0000000000002227. Epub 2023 May 19. Am J Gastroenterol. 2023. PMID: 37204227 Free PMC article.
Determination of Total Sennosides and Sennosides A, B, and A(1) in Senna Leaflets, Pods, and Tablets by Two-Dimensional qNMR.
Çiçek SS, Moreno Cardenas C, Girreser U. Çiçek SS, et al. Molecules. 2022 Oct 29;27(21):7349. doi: 10.3390/molecules27217349. Molecules. 2022. PMID: 36364175 Free PMC article.
In a second method, the use of 2D qNMR for the single analysis of sennosides A, B, and A(1) was evaluated with acceptable measurement times (31 min), accuracy (93.8%), and repeatability (5.4% and 5.6%) for the two major purgatives sennoside A and B. Ho …
In a second method, the use of 2D qNMR for the single analysis of sennosides A, B, and A(1) was evaluated with acceptable meas …
Sennosides A and B production by hairy roots of Senna alata (L.) Roxb.
Putalun W, Pimmeuangkao S, De-Eknamkul W, Tanaka H, Shoyama Y. Putalun W, et al. Z Naturforsch C J Biosci. 2006 May-Jun;61(5-6):367-71. doi: 10.1515/znc-2006-5-612. Z Naturforsch C J Biosci. 2006. PMID: 16869495 Free article.
Effects of sucrose contents and hormones on the growth and sennosides A, B production were investigated. Hairy roots cultured on hormone-free half-strength MS medium containing 5% sucrose under dark condition mostly stimulated the growth of hairy roots and increased …
Effects of sucrose contents and hormones on the growth and sennosides A, B production were investigated. Hairy roots cultured …
Didang Tang alleviates neuronal ferroptosis after intracerebral hemorrhage by modulating the PERK/eIF2α/ATF4/CHOP/GPX4 signaling pathway.
Lu J, Xu H, Li L, Tang X, Zhang Y, Zhang D, Xu P, Sun L, Wang J. Lu J, et al. Front Pharmacol. 2024 Oct 24;15:1472813. doi: 10.3389/fphar.2024.1472813. eCollection 2024. Front Pharmacol. 2024. PMID: 39525631 Free PMC article.
Molecular docking suggested that DDT components, such as sennoside B, amygdalin, rhein, and emodin, interact favorably with PERK/eIF2alpha/ATF4/CHOP signaling pathway proteins, highlighting their potential role in DDT's anti-ferroptosis effects. ...
Molecular docking suggested that DDT components, such as sennoside B, amygdalin, rhein, and emodin, interact favorably with PE …
[Determination of sennoside B, sennoside A and physcion in slimming health foods].
Diao F, Xie Q, Wu X, Liu C, Li X, Li Q. Diao F, et al. Wei Sheng Yan Jiu. 2020 Sep;49(5):809-814. doi: 10.19813/j.cnki.weishengyanjiu.2020.05.020. Wei Sheng Yan Jiu. 2020. PMID: 33070828 Chinese.
Sennoside A, sennoside B or physcion were detected in 19 out of 40 batches of samples. The content of sennoside A ranged from 0. 184 to 6. 33 mg/g and the content of sennoside B ranged from 0. 202 to 7. 23 mg/g. ...CONCLUSION: The method …
Sennoside A, sennoside B or physcion were detected in 19 out of 40 batches of samples. The content of sennoside …
Effects of sennosides A + B and bisacodyl on rat large intestine.
Leng-Peschlow E. Leng-Peschlow E. Pharmacology. 1989;38(5):310-8. doi: 10.1159/000138551. Pharmacology. 1989. PMID: 2762373
Oral and intracecal administration of bisacodyl or sennosides A + B (10-100 mg/kg each) to rats induced a similar quantity of soft feces within 24 h and a similar acceleration of large intestinal transit time, but in each case bisacodyl had a prolonged action. ...Bo …
Oral and intracecal administration of bisacodyl or sennosides A + B (10-100 mg/kg each) to rats induced a similar quantity of …
The senna drug and its chemistry.
Franz G. Franz G. Pharmacology. 1993 Oct;47 Suppl 1:2-6. doi: 10.1159/000139654. Pharmacology. 1993. PMID: 8234429 Review.
These were found to be dimeric products of aloe emodin and/or rhein which were named sennoside A and sennoside B. They both hydrolyze to give the aglycones sennidin A and B and two molecules of glucose. Later work confirmed these findings and further d …
These were found to be dimeric products of aloe emodin and/or rhein which were named sennoside A and sennoside B. They …
Evaluation of the Amounts of Sennosides A and B in Rhubarb-containing Kampo Medicines to Create a Ranking of Kampo Medicines for Appropriate Selection of Laxatives.
Ogawa K, Tashima A, Okazaki K, Morinaga O. Ogawa K, et al. J Anus Rectum Colon. 2021 Jul 29;5(3):229-236. doi: 10.23922/jarc.2020-102. eCollection 2021. J Anus Rectum Colon. 2021. PMID: 34395934 Free PMC article.
OBJECTIVES: To evaluate 20 Kampo medicines, which comprised 6 formulas, Otsujito, Junchoto, Tokakujokito, Bofutsushosan, Mashiningan, and Keishikashakuyakudaioto, from 7 brands, to create a ranking of Kampo medicines for appropriate selection of laxatives. METHODS: The amounts of …
OBJECTIVES: To evaluate 20 Kampo medicines, which comprised 6 formulas, Otsujito, Junchoto, Tokakujokito, Bofutsushosan, Mashiningan, and Ke …
Modulation of HIV-1 capsid multimerization by sennoside A and sennoside B via interaction with the NTD/CTD interface in capsid hexamer.
Zhang DW, Xu XS, Zhou R, Fu Z. Zhang DW, et al. Front Microbiol. 2023 Sep 25;14:1270258. doi: 10.3389/fmicb.2023.1270258. eCollection 2023. Front Microbiol. 2023. PMID: 37817748 Free PMC article.
We report the discovery of two natural compounds, sennoside A (SA) and sennoside B (SB), derived from medicinal plants that bind to this pocket in the C-terminal domain of capsid (CA CTD). ...
We report the discovery of two natural compounds, sennoside A (SA) and sennoside B (SB), derived from medicinal plants …
191 results