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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1986 2
1987 1
1988 6
1989 1
1990 5
1991 1
1992 9
1993 2
1994 13
1995 22
1996 21
1997 37
1998 42
1999 40
2000 56
2001 48
2002 46
2003 52
2004 52
2005 53
2006 61
2007 43
2008 39
2009 42
2010 44
2011 49
2012 45
2013 59
2014 59
2015 61
2016 35
2017 38
2018 45
2019 49
2020 44
2021 32
2022 28
2023 28
2024 15

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1,184 results

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Page 1
The clinical effectiveness of sertraline in primary care and the role of depression severity and duration (PANDA): a pragmatic, double-blind, placebo-controlled randomised trial.
Lewis G, Duffy L, Ades A, Amos R, Araya R, Brabyn S, Button KS, Churchill R, Derrick C, Dowrick C, Gilbody S, Fawsitt C, Hollingworth W, Jones V, Kendrick T, Kessler D, Kounali D, Khan N, Lanham P, Pervin J, Peters TJ, Riozzie D, Salaminios G, Thomas L, Welton NJ, Wiles N, Woodhouse R, Lewis G. Lewis G, et al. Lancet Psychiatry. 2019 Nov;6(11):903-914. doi: 10.1016/S2215-0366(19)30366-9. Epub 2019 Sep 19. Lancet Psychiatry. 2019. PMID: 31543474 Free PMC article. Clinical Trial.
We observed weak evidence that depressive symptoms were reduced by sertraline at 12 weeks. We recorded seven adverse events-four for sertraline and three for placebo, and adverse events did not differ by treatment allocation. Three adverse events were classified as …
We observed weak evidence that depressive symptoms were reduced by sertraline at 12 weeks. We recorded seven adverse events-four for …
Antidepressants or running therapy: Comparing effects on mental and physical health in patients with depression and anxiety disorders.
Verhoeven JE, Han LKM, Lever-van Milligen BA, Hu MX, Révész D, Hoogendoorn AW, Batelaan NM, van Schaik DJF, van Balkom AJLM, van Oppen P, Penninx BWJH. Verhoeven JE, et al. J Affect Disord. 2023 May 15;329:19-29. doi: 10.1016/j.jad.2023.02.064. Epub 2023 Feb 23. J Affect Disord. 2023. PMID: 36828150 Free article. Clinical Trial.
METHODS: According to a partially randomized patient preference design, 141 patients with depression and/or anxiety disorder were randomized or offered preferred 16-week treatment: antidepressant medication (escitalopram or sertraline) or group-based running therapy 2 per …
METHODS: According to a partially randomized patient preference design, 141 patients with depression and/or anxiety disorder were randomized …
Cognitive behavioral therapy, sertraline, or a combination in childhood anxiety.
Walkup JT, Albano AM, Piacentini J, Birmaher B, Compton SN, Sherrill JT, Ginsburg GS, Rynn MA, McCracken J, Waslick B, Iyengar S, March JS, Kendall PC. Walkup JT, et al. N Engl J Med. 2008 Dec 25;359(26):2753-66. doi: 10.1056/NEJMoa0804633. Epub 2008 Oct 30. N Engl J Med. 2008. PMID: 18974308 Free PMC article. Clinical Trial.
Results on the Pediatric Anxiety Rating Scale documented a similar magnitude and pattern of response; combination therapy had a greater response than cognitive behavioral therapy, which was equivalent to sertraline, and all therapies were superior to placebo. Adverse event …
Results on the Pediatric Anxiety Rating Scale documented a similar magnitude and pattern of response; combination therapy had a greater resp …
Exercise and pharmacotherapy in the treatment of major depressive disorder.
Blumenthal JA, Babyak MA, Doraiswamy PM, Watkins L, Hoffman BM, Barbour KA, Herman S, Craighead WE, Brosse AL, Waugh R, Hinderliter A, Sherwood A. Blumenthal JA, et al. Psychosom Med. 2007 Sep-Oct;69(7):587-96. doi: 10.1097/PSY.0b013e318148c19a. Epub 2007 Sep 10. Psychosom Med. 2007. PMID: 17846259 Free PMC article. Clinical Trial.
OBJECTIVE: To assess whether patients receiving aerobic exercise training performed either at home or in a supervised group setting achieve reductions in depression comparable to standard antidepressant medication (sertraline) and greater reductions in depression compared …
OBJECTIVE: To assess whether patients receiving aerobic exercise training performed either at home or in a supervised group setting achieve …
Rhodiola rosea versus sertraline for major depressive disorder: A randomized placebo-controlled trial.
Mao JJ, Xie SX, Zee J, Soeller I, Li QS, Rockwell K, Amsterdam JD. Mao JJ, et al. Phytomedicine. 2015 Mar 15;22(3):394-9. doi: 10.1016/j.phymed.2015.01.010. Epub 2015 Feb 23. Phytomedicine. 2015. PMID: 25837277 Free PMC article. Clinical Trial.
BACKGROUND: We performed a proof of concept trial to evaluate relative safety and efficacy of Rhodiola rosea (R. rosea) versus sertraline for mild to moderate major depressive disorder. HYPOTHESIS: We hypothesize that R. rosea would have similar therapeutic effects as s …
BACKGROUND: We performed a proof of concept trial to evaluate relative safety and efficacy of Rhodiola rosea (R. rosea) versus sertraline …
Cognitive-behavior therapy, sertraline, and their combination for children and adolescents with obsessive-compulsive disorder: the Pediatric OCD Treatment Study (POTS) randomized controlled trial.
Pediatric OCD Treatment Study (POTS) Team. Pediatric OCD Treatment Study (POTS) Team. JAMA. 2004 Oct 27;292(16):1969-76. doi: 10.1001/jama.292.16.1969. JAMA. 2004. PMID: 15507582 Clinical Trial.
OBJECTIVE: To evaluate the efficacy of CBT alone and medical management with the selective serotonin reuptake inhibitor sertraline alone, or CBT and sertraline combined, as initial treatment for children and adolescents with OCD. ...CBT alone did not differ from …
OBJECTIVE: To evaluate the efficacy of CBT alone and medical management with the selective serotonin reuptake inhibitor sertraline al …
Treatment Response Prediction in Major Depressive Disorder Using Multimodal MRI and Clinical Data: Secondary Analysis of a Randomized Clinical Trial.
Poirot MG, Ruhe HG, Mutsaerts HMM, Maximov II, Groote IR, Bjørnerud A, Marquering HA, Reneman L, Caan MWA. Poirot MG, et al. Am J Psychiatry. 2024 Mar 1;181(3):223-233. doi: 10.1176/appi.ajp.20230206. Epub 2024 Feb 7. Am J Psychiatry. 2024. PMID: 38321916 Clinical Trial.
External cross-validation on data from placebo nonresponders (bAcc=62%, AUROC=0.66) and placebo nonresponders who were switched to sertraline (bAcc=65%, AUROC=0.68) resulted in differences that suggest specificity for sertraline treatment compared with placebo treat …
External cross-validation on data from placebo nonresponders (bAcc=62%, AUROC=0.66) and placebo nonresponders who were switched to sertra …
Exercise treatment for major depression: maintenance of therapeutic benefit at 10 months.
Babyak M, Blumenthal JA, Herman S, Khatri P, Doraiswamy M, Moore K, Craighead WE, Baldewicz TT, Krishnan KR. Babyak M, et al. Psychosom Med. 2000 Sep-Oct;62(5):633-8. doi: 10.1097/00006842-200009000-00006. Psychosom Med. 2000. PMID: 11020092 Clinical Trial.
OBJECTIVE: The purpose of this study was to assess the status of 156 adult volunteers with major depressive disorder (MDD) 6 months after completion of a study in which they were randomly assigned to a 4-month course of aerobic exercise, sertraline therapy, or a combinatio …
OBJECTIVE: The purpose of this study was to assess the status of 156 adult volunteers with major depressive disorder (MDD) 6 months after co …
Physical exercise for late-life depression: Effects on symptom dimensions and time course.
Murri MB, Ekkekakis P, Menchetti M, Neviani F, Trevisani F, Tedeschi S, Latessa PM, Nerozzi E, Ermini G, Zocchi D, Squatrito S, Toni G, Cabassi A, Neri M, Zanetidou S, Amore M. Murri MB, et al. J Affect Disord. 2018 Apr 1;230:65-70. doi: 10.1016/j.jad.2018.01.004. J Affect Disord. 2018. PMID: 29407540 Clinical Trial.
METHODS: We analyzed data from the SEEDS study, a trial comparing the antidepressant effectiveness of sertraline (S) and sertraline plus exercise (S+EX). Exercise was delivered thrice weekly in small groups and monitored by heart rate meters. ...
METHODS: We analyzed data from the SEEDS study, a trial comparing the antidepressant effectiveness of sertraline (S) and se …
Agomelatine augmentation of sertraline in the treatment of moderate to severe obsessive-compulsive disorder: a randomized double-blinded placebo-controlled clinical trial.
Shokrani M, Askari S, Eissazade N, Shariat SV, Shariati B, Yarahmadi M, Shalbafan M. Shokrani M, et al. BMC Psychiatry. 2023 Sep 21;23(1):686. doi: 10.1186/s12888-023-05189-7. BMC Psychiatry. 2023. PMID: 37735631 Free PMC article. Clinical Trial.
They were assigned with sertraline (100 mg/day for the first 4 weeks and 200 mg/day for the next 8 weeks) and either agomelatine (25 mg/day) or placebo. ...CONCLUSION: Agomelatine in augmentation with sertraline is safe and tolerable in patients with moderate to sev …
They were assigned with sertraline (100 mg/day for the first 4 weeks and 200 mg/day for the next 8 weeks) and either agomelatine (25 …
1,184 results