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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1950 5
1951 4
1953 3
1954 4
1955 2
1956 1
1957 2
1958 3
1959 1
1960 2
1961 4
1962 2
1963 2
1964 2
1965 1
1975 3
1977 2
1979 3
1980 2
1981 5
1982 1
1983 2
1984 2
1985 1
1986 1
1987 28
1988 18
1989 16
1990 29
1991 34
1992 62
1993 86
1994 111
1995 144
1996 172
1997 219
1998 266
1999 270
2000 285
2001 319
2002 317
2003 321
2004 366
2005 368
2006 378
2007 377
2008 340
2009 419
2010 411
2011 445
2012 452
2013 484
2014 524
2015 550
2016 526
2017 543
2018 472
2019 509
2020 617
2021 577
2022 582
2023 575
2024 348

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11,596 results

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Page 1
Mechanistic insight into sevoflurane-associated developmental neurotoxicity.
Sun M, Xie Z, Zhang J, Leng Y. Sun M, et al. Cell Biol Toxicol. 2022 Dec;38(6):927-943. doi: 10.1007/s10565-021-09677-y. Epub 2021 Nov 12. Cell Biol Toxicol. 2022. PMID: 34766256 Free PMC article. Review.
Short or single exposure to sevoflurane has a weak effect on cognitive function, while long or repeated exposure to general anesthetics may cause cognitive dysfunction. This review focuses on the mechanisms by which sevoflurane exposure during development may induce …
Short or single exposure to sevoflurane has a weak effect on cognitive function, while long or repeated exposure to general anestheti …
A Sleep-Specific Midbrain Target for Sevoflurane Anesthesia.
Yi T, Wang N, Huang J, Wang Y, Ren S, Hu Y, Xia J, Liao Y, Li X, Luo F, Ouyang Q, Li Y, Zheng Z, Xiao Q, Ren R, Yao Z, Tang X, Wang Y, Chen X, He C, Li H, Hu Z. Yi T, et al. Adv Sci (Weinh). 2023 May;10(15):e2300189. doi: 10.1002/advs.202300189. Epub 2023 Mar 24. Adv Sci (Weinh). 2023. PMID: 36961096 Free PMC article.
Furthermore, growth hormone secretagogue receptor (GHSR) is highly enriched in sevoflurane-activated UCN1(+) /CART(+) cells and is necessary for sleep induction. Blockade of GHSR abolishes the excitatory effect of sevoflurane on UCN1(+) /CART(+) neurons and attenuat …
Furthermore, growth hormone secretagogue receptor (GHSR) is highly enriched in sevoflurane-activated UCN1(+) /CART(+) cells and is ne …
Prolonged anesthesia induces neuroinflammation and complement-mediated microglial synaptic elimination involved in neurocognitive dysfunction and anxiety-like behaviors.
Xu F, Han L, Wang Y, Deng D, Ding Y, Zhao S, Zhang Q, Ma L, Chen X. Xu F, et al. BMC Med. 2023 Jan 5;21(1):7. doi: 10.1186/s12916-022-02705-6. BMC Med. 2023. PMID: 36600274 Free PMC article.
The neuromorphopathological underpinnings of anesthesia-induced neurotoxicity have remained elusive. METHODS: Prolonged anesthesia with sevoflurane was used to establish the sevoflurane-induced neurotoxicity (SIN) animal model. ...
The neuromorphopathological underpinnings of anesthesia-induced neurotoxicity have remained elusive. METHODS: Prolonged anesthesia with s
Prolonged sedation with sevoflurane in comparison to intravenous sedation in critically ill patients - A randomized controlled trial.
Soukup J, Michel P, Christel A, Schittek GA, Wagner NM, Kellner P. Soukup J, et al. J Crit Care. 2023 Apr;74:154251. doi: 10.1016/j.jcrc.2022.154251. Epub 2023 Jan 12. J Crit Care. 2023. PMID: 36640476 Free article. Clinical Trial.
METHODS: In this prospective, randomized-controlled phase-IIb monocentric clinical-trial ICU patients requiring at least 48 h of sedation were randomized to receive sevoflurane (S) or propofol/midazolam (P). Sedation quality was monitored using the Richmond-Agitatio …
METHODS: In this prospective, randomized-controlled phase-IIb monocentric clinical-trial ICU patients requiring at least 48 h of sedation we …
Renal function during sevoflurane or total intravenous propofol anaesthesia: a single-centre parallel randomised controlled study.
Franzén S, Semenas E, Taavo M, Mårtensson J, Larsson A, Frithiof R. Franzén S, et al. Br J Anaesth. 2022 May;128(5):838-848. doi: 10.1016/j.bja.2022.02.030. Epub 2022 Mar 10. Br J Anaesth. 2022. PMID: 35279277 Free article. Clinical Trial.
We investigated renal function in patients anaesthetised with propofol or sevoflurane before surgery and postoperatively. METHODS: Patients with ASA physical status 1-2 planned for spinal surgery were randomised to propofol or sevoflurane anaesthesia. ...Kidney inju …
We investigated renal function in patients anaesthetised with propofol or sevoflurane before surgery and postoperatively. METHODS: Pa …
Dysregulation of iron homeostasis and ferroptosis in sevoflurane and isoflurane associated perioperative neurocognitive disorders.
Miao M, Han Y, Wang Y, Wang J, Zhu R, Yang Y, Fu N, Li N, Sun M, Zhang J. Miao M, et al. CNS Neurosci Ther. 2024 Feb;30(2):e14553. doi: 10.1111/cns.14553. CNS Neurosci Ther. 2024. PMID: 38334231 Free PMC article. Review.
In recent years, sevoflurane and isoflurane are the most popular anesthetics in general anesthesia for their safe, rapid onset, and well tolerant. ...Evidence indicates that iron dyshomeostasis and ferroptosis may establish a role in neurotoxicity of sevoflurane and …
In recent years, sevoflurane and isoflurane are the most popular anesthetics in general anesthesia for their safe, rapid onset, and w …
Long-term survival in older patients given propofol or sevoflurane anaesthesia for major cancer surgery: follow-up of a multicentre randomised trial.
Cao SJ, Zhang Y, Zhang YX, Zhao W, Pan LH, Sun XD, Jia Z, Ouyang W, Ye QS, Zhang FX, Guo YQ, Ai YQ, Zhao BJ, Yu JB, Liu ZH, Yin N, Li XY, Ma JH, Li HJ, Wang MR, Sessler DI, Ma D, Wang DX; First Study of Perioperative Organ Protection (SPOP1) investigators. Cao SJ, et al. Br J Anaesth. 2023 Aug;131(2):266-275. doi: 10.1016/j.bja.2023.01.023. Epub 2023 Jun 4. Br J Anaesth. 2023. PMID: 37474242 Free article. Clinical Trial.
They were randomised to either propofol-based i.v. anaesthesia or to sevoflurane-based inhalational anaesthesia. The primary endpoint was overall survival after surgery. ...Event-free survival was 294/598 (49%) in patients given propofol anaesthesia vs 274/597 (46%) given …
They were randomised to either propofol-based i.v. anaesthesia or to sevoflurane-based inhalational anaesthesia. The primary endpoint …
Human neural correlates of sevoflurane-induced unconsciousness.
Palanca BJA, Avidan MS, Mashour GA. Palanca BJA, et al. Br J Anaesth. 2017 Oct 1;119(4):573-582. doi: 10.1093/bja/aex244. Br J Anaesth. 2017. PMID: 29121298 Free PMC article. Review.
Sevoflurane, a volatile anaesthetic agent well-tolerated for inhalation induction, provides a useful opportunity to elucidate the processes whereby halogenated ethers disrupt consciousness and cognition. ...Combined EEG and PET investigations have identified changes in cer
Sevoflurane, a volatile anaesthetic agent well-tolerated for inhalation induction, provides a useful opportunity to elucidate the pro
Topical sevofluran: a galenic experience.
Fernández-Ginés FD, Gerónimo-Pardo M, Cortiñas-Sáenz M. Fernández-Ginés FD, et al. Farm Hosp. 2021 Jul 21;45(5):277-281. Farm Hosp. 2021. PMID: 34806589 Review. English.
To avoid manipulation of this volatile liquid, we have developed a new formulation of sevoflurane in gel form, which has made it possible to successfully apply sevoflurane in the context of painful pathologies where the skin remains intact. Furthermore, these types …
To avoid manipulation of this volatile liquid, we have developed a new formulation of sevoflurane in gel form, which has made it poss …
The protective effects of sevoflurane on subarachnoid hemorrhage.
Xing W, Zhao J, Liu J, Liu Z, Chen G. Xing W, et al. Med Gas Res. 2024 Jan-Mar;14(1):1-5. doi: 10.4103/2045-9912.379167. Med Gas Res. 2024. PMID: 37721248 Free PMC article. Review.
Sevoflurane has become an important volatile anesthetic in clinic and has been widely studied in recent years. Numerous studies have demonstrated the efficacy of sevoflurane in safeguarding against brain damage across various domains. ...
Sevoflurane has become an important volatile anesthetic in clinic and has been widely studied in recent years. Numerous studies have
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