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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 1
1994 1
1996 2
1997 8
1998 141
1999 247
2000 249
2001 294
2002 361
2003 364
2004 387
2005 445
2006 488
2007 456
2008 443
2009 402
2010 412
2011 394
2012 415
2013 460
2014 431
2015 418
2016 414
2017 393
2018 383
2019 367
2020 390
2021 402
2022 287
2023 291
2024 138

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8,813 results

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Page 1
Direct comparison of tadalafil with sildenafil for the treatment of erectile dysfunction: a systematic review and meta-analysis.
Gong B, Ma M, Xie W, Yang X, Huang Y, Sun T, Luo Y, Huang J. Gong B, et al. Int Urol Nephrol. 2017 Oct;49(10):1731-1740. doi: 10.1007/s11255-017-1644-5. Epub 2017 Jul 24. Int Urol Nephrol. 2017. PMID: 28741090 Free PMC article. Review.
However, compared with sildenafil, tadalafil significantly improved psychological outcomes. Furthermore, the patients and their partners preferred tadalafil over sildenafil, and no significant difference was found in the adherence and persistence rates between tadal …
However, compared with sildenafil, tadalafil significantly improved psychological outcomes. Furthermore, the patients and their partn …
Reply.
Groom KM, Ganzevoort W, Alfirevic Z, Lim K, Papageorghiou AT; STRIDER Consortium. Groom KM, et al. Ultrasound Obstet Gynecol. 2019 Feb;53(2):275. doi: 10.1002/uog.20202. Ultrasound Obstet Gynecol. 2019. PMID: 30741451 Free article. No abstract available.
Endophenotype-based in silico network medicine discovery combined with insurance record data mining identifies sildenafil as a candidate drug for Alzheimer's disease.
Fang J, Zhang P, Zhou Y, Chiang CW, Tan J, Hou Y, Stauffer S, Li L, Pieper AA, Cummings J, Cheng F. Fang J, et al. Nat Aging. 2021 Dec;1(12):1175-1188. doi: 10.1038/s43587-021-00138-z. Epub 2021 Dec 6. Nat Aging. 2021. PMID: 35572351 Free PMC article. Clinical Trial.
We developed an endophenotype disease module-based methodology for Alzheimer's disease (AD) drug repurposing and identified sildenafil as a potential disease risk modifier. Based on retrospective case-control pharmacoepidemiologic analyses of insurance claims data for 7.23 …
We developed an endophenotype disease module-based methodology for Alzheimer's disease (AD) drug repurposing and identified sildenafil
Sildenafil for improving outcomes in patients with corrected valvular heart disease and persistent pulmonary hypertension: a multicenter, double-blind, randomized clinical trial.
Bermejo J, Yotti R, García-Orta R, Sánchez-Fernández PL, Castaño M, Segovia-Cubero J, Escribano-Subías P, San Román JA, Borrás X, Alonso-Gómez A, Botas J, Crespo-Leiro MG, Velasco S, Bayés-Genís A, López A, Muñoz-Aguilera R, de Teresa E, González-Juanatey JR, Evangelista A, Mombiela T, González-Mansilla A, Elízaga J, Martín-Moreiras J, González-Santos JM, Moreno-Escobar E, Fernández-Avilés F; Sildenafil for Improving Outcomes after VAlvular Correction (SIOVAC) investigators. Bermejo J, et al. Eur Heart J. 2018 Apr 14;39(15):1255-1264. doi: 10.1093/eurheartj/ehx700. Eur Heart J. 2018. PMID: 29281101 Free PMC article. Clinical Trial.
We assigned 200 patients to receive sildenafil (40 mg three times daily, n = 104) or placebo (n = 96) for 6 months. ...Off-label usage of sildenafil for treating this source of left heart disease PH should be avoided. ...
We assigned 200 patients to receive sildenafil (40 mg three times daily, n = 104) or placebo (n = 96) for 6 months. ...Off-label usag …
Because it's embarrassing?
Ørstavik RE. Ørstavik RE. Tidsskr Nor Laegeforen. 2019 Sep 23;139(13). doi: 10.4045/tidsskr.19.0578. Print 2019 Sep 24. Tidsskr Nor Laegeforen. 2019. PMID: 31556514 Free article. English, Norwegian. No abstract available.
Sildenafil in ophthalmology: An update.
Arora S, Surakiatchanukul T, Arora T, Cagini C, Lupidi M, Chhablani J. Arora S, et al. Surv Ophthalmol. 2022 Mar-Apr;67(2):463-487. doi: 10.1016/j.survophthal.2021.06.004. Epub 2021 Jun 25. Surv Ophthalmol. 2022. PMID: 34175342 Review.
Sildenafil citrate, a selective oral phosphodiesterase 5 inhibitor, is a widely used drug for erectile dysfunction that acts by elevating cGMP levels and causing smooth muscle relaxation. ...Recent ocular imaging developments have further revealed the influence of
Sildenafil citrate, a selective oral phosphodiesterase 5 inhibitor, is a widely used drug for erectile dysfunction that acts b
Reply.
Krishnan US, Krishnan SS, Abman SH. Krishnan US, et al. J Pediatr. 2019 Oct;213:251. doi: 10.1016/j.jpeds.2019.06.020. Epub 2019 Jul 9. J Pediatr. 2019. PMID: 31300312 No abstract available.
Sildenafil as a Candidate Drug for Alzheimer's Disease: Real-World Patient Data Observation and Mechanistic Observations from Patient-Induced Pluripotent Stem Cell-Derived Neurons.
Gohel D, Zhang P, Gupta AK, Li Y, Chiang CW, Li L, Hou Y, Pieper AA, Cummings J, Cheng F. Gohel D, et al. J Alzheimers Dis. 2024;98(2):643-657. doi: 10.3233/JAD-231391. J Alzheimers Dis. 2024. PMID: 38427489 Free PMC article.
We used both familial and sporadic AD patient induced pluripotent stem cells (iPSC) derived neurons to evaluate the sildenafil's mechanism-of-action. RESULTS: We showed that sildenafil usage is associated with reduced likelihood of AD across four new drug com …
We used both familial and sporadic AD patient induced pluripotent stem cells (iPSC) derived neurons to evaluate the sildenafil's
Sildenafil/Viagra in the treatment of premature ejaculation.
Krishnappa P, Fernandez-Pascual E, Carballido J, Martinez-Salamanca JI. Krishnappa P, et al. Int J Impot Res. 2019 Mar;31(2):65-70. doi: 10.1038/s41443-018-0099-2. Epub 2019 Mar 5. Int J Impot Res. 2019. PMID: 30837718 Review.
Since then the sexual medicine experts have been prescribing sildenafil in erectile dysfunction with acceptable minor adverse events. But the use of sildenafil in premature ejaculation (PE) is still debated. 2018 being the 20th anniversary of sildenafil, we h …
Since then the sexual medicine experts have been prescribing sildenafil in erectile dysfunction with acceptable minor adverse events. …
8,813 results