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Page 1
Full-length recombinant antibodies from Escherichia coli: production, characterization, effector function (Fc) engineering, and clinical evaluation.
Rashid MH. Rashid MH. MAbs. 2022 Jan-Dec;14(1):2111748. doi: 10.1080/19420862.2022.2111748. MAbs. 2022. PMID: 36018829 Free PMC article. Review.
This review summarizes recent research, preclinical advancements, and clinical development of E. coli-produced aglycosylated therapeutic antibodies as monoclonal, bispecific, and antibody-drug conjugates for use in autoimmune, oncology, and immuno-oncology areas.Abbreviations: AD …
This review summarizes recent research, preclinical advancements, and clinical development of E. coli-produced aglycosylated therapeutic ant …
Grafting of Crown Ether and Cryptand Macrocycles on Large Pore Stellate Mesoporous Silica for Sodium Cation Extraction.
Duenas-Ramirez P, Bertagnolli C, Weiss R, Bizeau J, Jierry L, Choquet P, Zaloszyc A, Bégin-Colin S, Mertz D. Duenas-Ramirez P, et al. Molecules. 2023 Jun 7;28(12):4622. doi: 10.3390/molecules28124622. Molecules. 2023. PMID: 37375176 Free PMC article.
Regarding sodium capture in water, C221 cryptand-grafted STMS showed better capture efficiency than CE-STMS due to higher sodium atom chelation in the cryptand cage (Na(+) coverage of 15.5% vs. 3.7%). ...Results obtained indicate that C221 cryptand-grafted STMS are …
Regarding sodium capture in water, C221 cryptand-grafted STMS showed better capture efficiency than CE-STMS due to higher sodium …
Hyponatremia and hypokalemia in patients on peritoneal dialysis.
Zanger R. Zanger R. Semin Dial. 2010 Nov-Dec;23(6):575-80. doi: 10.1111/j.1525-139X.2010.00789.x. Epub 2010 Dec 2. Semin Dial. 2010. PMID: 21121953 Review.
Hyponatremia may be caused by excessive thirst, a particular problem in patients on PD. Consistent with the relationship among the serum sodium concentration, total body cation content, and total body water, hyponatremia may also be caused by total body potas …
Hyponatremia may be caused by excessive thirst, a particular problem in patients on PD. Consistent with the relationship among the se …
Sodium Ion-Conducting Electrolytes Based on Chloroaluminate Ionic Liquids and delta-NaCl.
Kumar S, Raghupathy R, Vezzù K, Garaga MN, Zhu X, Greenbaum S, Di Noto V, Vittadello M. Kumar S, et al. ChemSusChem. 2024 Oct 21;17(20):e202400863. doi: 10.1002/cssc.202400863. Epub 2024 Jul 31. ChemSusChem. 2024. PMID: 39082857
Sodium-containing ionic liquids are very promising candidates as ion-conducting materials in alternative to electrolytes based on lithium chemistry. ...Reversible deposition of Na and Al-containing species take place with high Coulombic efficiency (up to 97 %) and a high N …
Sodium-containing ionic liquids are very promising candidates as ion-conducting materials in alternative to electrolytes based on lit …
Molecular Modeling of Cardiac Sodium Channel with Mexiletine.
Zhorov BS. Zhorov BS. Membranes (Basel). 2022 Dec 10;12(12):1252. doi: 10.3390/membranes12121252. Membranes (Basel). 2022. PMID: 36557159 Free PMC article.
A sodium channel blocker mexiletine (MEX) is used to treat chronic pain, myotonia and some arrhythmias. Mutations in the pore domain (PD) of voltage-gated sodium channels differently affect tonic block (TB) and use-dependent block (UDB) by MEX. ...
A sodium channel blocker mexiletine (MEX) is used to treat chronic pain, myotonia and some arrhythmias. Mutations in the pore domain …
Chronic and acute exposure to rotenone reveals distinct Parkinson's disease-related phenotypes in human iPSC-derived peripheral neurons.
Saleh MA, Amer-Sarsour F, Berant A, Pasmanik-Chor M, Kobo H, Sharabi Y, Vatine GD, Ashkenazi A. Saleh MA, et al. Free Radic Biol Med. 2024 Mar;213:164-173. doi: 10.1016/j.freeradbiomed.2024.01.016. Epub 2024 Jan 19. Free Radic Biol Med. 2024. PMID: 38246514 Free article.
Peripheral autonomic nervous system (P-ANS) dysfunction is a critical non-motor phenotype of Parkinson's disease (PD). The majority of PD cases are sporadic and lack identified PD-associated genes involved. ...Moreover, we identified the sodium voltage …
Peripheral autonomic nervous system (P-ANS) dysfunction is a critical non-motor phenotype of Parkinson's disease (PD). The majority o …
Body sodium, potassium and water in peritoneal dialysis-associated hyponatremia.
Sun Y, Mills D, Ing TS, Shapiro JI, Tzamaloukas AH. Sun Y, et al. Perit Dial Int. 2014 May;34(3):253-9. doi: 10.3747/pdi.2012.00201. Perit Dial Int. 2014. PMID: 24863873 Free PMC article.
OBJECTIVE: This report presents a method quantitatively analyzing abnormalities of body water and monovalent cations (sodium plus potassium) in patients on peritoneal dialysis (PD) with true hyponatremia. METHODS: It is well known that in the face of euglycemia seru …
OBJECTIVE: This report presents a method quantitatively analyzing abnormalities of body water and monovalent cations (sodium plus pot …
In vitro antibacterial activities of the fluoroquinolones PD 117596, PD 124816, and PD 127391.
Cohen MA, Huband MD, Mailloux GB, Yoder SL, Roland GE, Heifetz CL. Cohen MA, et al. Diagn Microbiol Infect Dis. 1991 May-Jun;14(3):245-58. doi: 10.1016/0732-8893(91)90039-i. Diagn Microbiol Infect Dis. 1991. PMID: 1889177
Three new aminopyrrolidine-substituted fluorocyclopropyl quinolones--PD 117596, PD 124816, and PD 127391--were tested for in vitro antibacterial activity against 349 bacterial strains, which are primarily clinical isolates. ...The activities of the new quinol …
Three new aminopyrrolidine-substituted fluorocyclopropyl quinolones--PD 117596, PD 124816, and PD 127391--were tested f …
77 results