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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 3
1977 20
1978 16
1979 37
1980 39
1981 34
1982 40
1983 39
1984 50
1985 53
1986 67
1987 48
1988 32
1989 29
1990 31
1991 31
1992 28
1993 33
1994 46
1995 48
1996 51
1997 60
1998 48
1999 65
2000 65
2001 68
2002 86
2003 72
2004 77
2005 75
2006 73
2007 76
2008 76
2009 60
2010 45
2011 61
2012 69
2013 54
2014 56
2015 52
2016 42
2017 37
2018 37
2019 37
2020 31
2021 36
2022 33
2023 32
2024 27
2025 23
2026 15

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2,226 results

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Page 1
Sulindac sulfide inhibits Ras signaling.
Herrmann C, Block C, Geisen C, Haas K, Weber C, Winde G, Möröy T, Müller O. Herrmann C, et al. Oncogene. 1998 Oct 8;17(14):1769-76. doi: 10.1038/sj.onc.1202085. Oncogene. 1998. PMID: 9778042
In vivo the prodrug sulindac, is converted into the metabolite sulindac sulfide. We found that sulindac sulfide strongly inhibits Ras induced malignant transformation and Ras/Raf dependent transactivation. Sulindac sulfide decreases the Ras induced act …
In vivo the prodrug sulindac, is converted into the metabolite sulindac sulfide. We found that sulindac sulfide strongl …
Sulindac and polyp regression.
Giardiello FM. Giardiello FM. Cancer Metastasis Rev. 1994 Dec;13(3-4):279-83. doi: 10.1007/BF00666098. Cancer Metastasis Rev. 1994. PMID: 7712590 Review.
Sulindac is useful in regression of adenomatous polyps. In addition to orally administered sulindac, rectal preparations also appear to be efficacious [32]. ...Also, investigators noted that after discontinuation of sulindac adenomas recurred. Sulindac …
Sulindac is useful in regression of adenomatous polyps. In addition to orally administered sulindac, rectal preparations also …
Sulindac exhibits anti-proliferative and anti-invasive effects in uterine serous carcinoma cells.
Chen S, Kong W, Shen X, Deng B, Haag J, Sinha N, John C, Sun W, Zhou C, Bae-Jump VL. Chen S, et al. J Cancer Res Clin Oncol. 2024 Aug 28;150(8):402. doi: 10.1007/s00432-024-05926-9. J Cancer Res Clin Oncol. 2024. PMID: 39198302 Free PMC article.
This study aims to evaluate the effect of sulindac on cell proliferation and invasion in USC cells. METHODS: Human USC cell lines ARK-1 and SPEC2 were treated with different concentrations of sulindac. ...Western blotting was used to analyze the changes in protein e …
This study aims to evaluate the effect of sulindac on cell proliferation and invasion in USC cells. METHODS: Human USC cell lines ARK …
Sulindac hepatotoxicity.
Fagan EA, Walford N, Hodgson HJ. Fagan EA, et al. Gut. 1983 Dec;24(12):1199. doi: 10.1136/gut.24.12.1199. Gut. 1983. PMID: 6642281 Free PMC article. No abstract available.
Sulindac-associated choledocholithiasis.
Eda A, Yanaka I, Tamada K, Wada S, Tomiyama T, Sugano K. Eda A, et al. Am J Gastroenterol. 2001 Jul;96(7):2283-5. doi: 10.1111/j.1572-0241.2001.03995.x. Am J Gastroenterol. 2001. PMID: 11467685 No abstract available.
Sulindac hepatotoxicity.
Whittaker SJ, Amar JN, Wanless IR, Heathcote J. Whittaker SJ, et al. Gut. 1982 Oct;23(10):875-7. doi: 10.1136/gut.23.10.875. Gut. 1982. PMID: 7117907 Free PMC article.
Two patients who developed painless jaundice while taking sulindac are described. Rechallenge in one case confirmed the association of hepatic damage with sulindac administration. ...
Two patients who developed painless jaundice while taking sulindac are described. Rechallenge in one case confirmed the association o …
Sulindac-induced anaphylaxis.
Burrish GF, Kaatz BL. Burrish GF, et al. Ann Emerg Med. 1981 Mar;10(3):154-5. doi: 10.1016/s0196-0644(81)80383-6. Ann Emerg Med. 1981. PMID: 7469157
This communication describes the first known report of sulindac-induced anaphylaxis. A 17-year-old patient who ingested a single tablet of sulindac developed pruritus, hives, and dyspnea. ...
This communication describes the first known report of sulindac-induced anaphylaxis. A 17-year-old patient who ingested a single tabl …
OSI-461 (OSI).
Galmarini CM. Galmarini CM. Curr Opin Investig Drugs. 2004 Jun;5(6):648-56. Curr Opin Investig Drugs. 2004. PMID: 15242254 Review.
Photoisomerization of Sulindac and Ozagrel Hydrochloride by Vitamin B(2) Catalyst Under Visible Light Irradiation.
Suga M, Makino K, Tabata H, Oshitari T, Natsugari H, Takahashi H. Suga M, et al. Pharm Res. 2022 Mar;39(3):577-586. doi: 10.1007/s11095-022-03203-3. Epub 2022 Mar 1. Pharm Res. 2022. PMID: 35233730
This study focused on light-induced isomerization of sulindac and ozagrel hydrochloride catalyzed by concomitant vitamin B(2) under light-emitting diode (LED) or fluorescent light. ...Furthermore, ozagrel hydrochloride was more prone to isomerization than sulindac. …
This study focused on light-induced isomerization of sulindac and ozagrel hydrochloride catalyzed by concomitant vitamin B(2) under l …
Methylation in the p21WAF1/cip1 promoter of Apc+/-, p21+/- mice and lack of response to sulindac.
Yang W, Bancroft L, Augenlicht LH. Yang W, et al. Oncogene. 2005 Mar 17;24(12):2104-9. doi: 10.1038/sj.onc.1208444. Oncogene. 2005. PMID: 15688007
Our previous work demonstrated that inactivation of a single p21 allele in Apc1638+/- mice was sufficient to accelerate Apc-initiated tumor formation, and that inactivation of only one p21 allele was also sufficient to abrogate duodenal tumor inhibition by sulindac, a nons …
Our previous work demonstrated that inactivation of a single p21 allele in Apc1638+/- mice was sufficient to accelerate Apc-initiated tumor …
2,226 results