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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 3
2002 19
2003 49
2004 94
2005 116
2006 142
2007 109
2008 114
2009 141
2010 141
2011 125
2012 172
2013 187
2014 191
2015 184
2016 161
2017 180
2018 159
2019 197
2020 200
2021 185
2022 193
2023 62

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2,680 results

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Page 1
Diagnosis and Treatment of Pulmonary Arterial Hypertension: A Review.
Ruopp NF, Cockrill BA. Ruopp NF, et al. JAMA. 2022 Apr 12;327(14):1379-1391. doi: 10.1001/jama.2022.4402. JAMA. 2022. PMID: 35412560 Review.
Currently approved therapy for PAH consists of drugs that enhance the nitric oxide-cyclic guanosine monophosphate biological pathway (sildenafil, tadalafil, or riociguat), prostacyclin pathway agonists (epoprostenol or treprostinil), and endothelin pathway antagonists (bos …
Currently approved therapy for PAH consists of drugs that enhance the nitric oxide-cyclic guanosine monophosphate biological pathway (silden …
Tadalafil for the treatment of benign prostatic hyperplasia.
Mónica FZ, De Nucci G. Mónica FZ, et al. Expert Opin Pharmacother. 2019 Jun;20(8):929-937. doi: 10.1080/14656566.2019.1589452. Epub 2019 Mar 22. Expert Opin Pharmacother. 2019. PMID: 30901259 Review.
Areas covered: This article reviews the major preclinical and clinical data on PDE5 inhibitors with a specific focus on tadalafil. It includes details of the role of the nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) - PDE5 pathway in the LUT organs (bladder and p …
Areas covered: This article reviews the major preclinical and clinical data on PDE5 inhibitors with a specific focus on tadalafil. It …
Tadalafil Alone or in Combination with Tamsulosin for the Management for LUTS/BPH and ED.
Sebastianelli A, Spatafora P, Morselli S, Vignozzi L, Serni S, McVary KT, Kaplan S, Gravas S, Chapple C, Gacci M. Sebastianelli A, et al. Curr Urol Rep. 2020 Oct 27;21(12):56. doi: 10.1007/s11934-020-01009-7. Curr Urol Rep. 2020. PMID: 33108544 Free PMC article. Review.
After discontinuation of tamsulosin or tadalafil in patients previously treated with their combination, the improvement of LUTS retains significance compared with baseline. Tadalafil 5 mg should be considered a primary treatment option for patients with LUTS/BPH and …
After discontinuation of tamsulosin or tadalafil in patients previously treated with their combination, the improvement of LUTS retai …
Pharmacotherapy for pulmonary arterial hypertension.
Burki TK. Burki TK. Lancet Respir Med. 2020 Nov;8(11):e81. doi: 10.1016/S2213-2600(20)30394-5. Epub 2020 Aug 25. Lancet Respir Med. 2020. PMID: 32857988 Free PMC article. Clinical Trial. No abstract available.
Direct comparison of tadalafil with sildenafil for the treatment of erectile dysfunction: a systematic review and meta-analysis.
Gong B, Ma M, Xie W, Yang X, Huang Y, Sun T, Luo Y, Huang J. Gong B, et al. Int Urol Nephrol. 2017 Oct;49(10):1731-1740. doi: 10.1007/s11255-017-1644-5. Epub 2017 Jul 24. Int Urol Nephrol. 2017. PMID: 28741090 Free PMC article. Review.
However, compared with sildenafil, tadalafil significantly improved psychological outcomes. Furthermore, the patients and their partners preferred tadalafil over sildenafil, and no significant difference was found in the adherence and persistence rates between ta
However, compared with sildenafil, tadalafil significantly improved psychological outcomes. Furthermore, the patients and their partn …
Three- Versus Two-Drug Therapy for Patients With Newly Diagnosed Pulmonary Arterial Hypertension.
Chin KM, Sitbon O, Doelberg M, Feldman J, Gibbs JSR, Grünig E, Hoeper MM, Martin N, Mathai SC, McLaughlin VV, Perchenet L, Poch D, Saggar R, Simonneau G, Galiè N. Chin KM, et al. J Am Coll Cardiol. 2021 Oct 5;78(14):1393-1403. doi: 10.1016/j.jacc.2021.07.057. J Am Coll Cardiol. 2021. PMID: 34593120 Free article. Clinical Trial.
OBJECTIVES: TRITON (The Efficacy and Safety of Initial Triple Versus Initial Dual Oral Combination Therapy in Patients With Newly Diagnosed Pulmonary Arterial Hypertension; NCT02558231), a multicenter, double-blind, randomized phase 3b study, evaluated initial triple (macitentan, …
OBJECTIVES: TRITON (The Efficacy and Safety of Initial Triple Versus Initial Dual Oral Combination Therapy in Patients With Newly Diagnosed …
Otorhinolaryngological adverse effects of urological drugs.
Maia NPD, Lopes KC, Ganança FF. Maia NPD, et al. Int Braz J Urol. 2021 Jul-Aug;47(4):747-752. doi: 10.1590/S1677-5538.IBJU.2021.99.06. Int Braz J Urol. 2021. PMID: 33566468 Free PMC article. Review.
MATERIALS AND METHODS: A review of the scientific literature was performed using a combination of specific descriptors (side effect, adverse effect, scopolamine, sildenafil, tadalafil, vardenafil, oxybutynin, tolterodine, spironolactone, furosemide, hydrochlorothiazide, do …
MATERIALS AND METHODS: A review of the scientific literature was performed using a combination of specific descriptors (side effect, adverse …
Initial combination therapy of macitentan and tadalafil in pulmonary arterial hypertension.
Sitbon O, Cottin V, Canuet M, Clerson P, Gressin V, Perchenet L, Bertoletti L, Bouvaist H, Picard F, Prévot G, Bergot E, Simonneau G. Sitbon O, et al. Eur Respir J. 2020 Sep 3;56(3):2000673. doi: 10.1183/13993003.00673-2020. Print 2020 Sep. Eur Respir J. 2020. PMID: 32350101 Free PMC article.
Initial combination therapy with macitentan and tadalafil is well tolerated and improves cardiopulmonary haemodynamics and functional capacity in newly diagnosed PAH patients https://bit.ly/3aWZagH Initial combination therapy plays a central role in managing pulmonary arte …
Initial combination therapy with macitentan and tadalafil is well tolerated and improves cardiopulmonary haemodynamics and functional …
Tadalafil 5 mg Once Daily Improves Lower Urinary Tract Symptoms and Erectile Dysfunction: A Systematic Review and Meta-analysis.
Wang Y, Bao Y, Liu J, Duan L, Cui Y. Wang Y, et al. Low Urin Tract Symptoms. 2018 Jan;10(1):84-92. doi: 10.1111/luts.12144. Epub 2016 Nov 5. Low Urin Tract Symptoms. 2018. PMID: 29341503 Review.
RESULTS: Thirteen publications involving a total of 3973 patients were used in the analysis, including 13 RCTs that compared tadalafil 5 mg once-daily with placebo. We found that tadalafil 5 mg once-daily was effective in improving LUTS suggestive of BPH and treatin …
RESULTS: Thirteen publications involving a total of 3973 patients were used in the analysis, including 13 RCTs that compared tadalafil
Lodenafil.
Alshehri YM, Al-Majed AA, Attwa MW, Bakheit AH. Alshehri YM, et al. Profiles Drug Subst Excip Relat Methodol. 2022;47:113-147. doi: 10.1016/bs.podrm.2021.10.004. Epub 2021 Dec 7. Profiles Drug Subst Excip Relat Methodol. 2022. PMID: 35396013 Review.
Lodenafil is a class of drugs called an inhibitor of PDE5 which also include a wide range of other erectile medicines, such as sildenafil, tadalafil and vardenafil. It is part of a new generation of PDE5 inhibitors that includes udenafil and avanafil. ...
Lodenafil is a class of drugs called an inhibitor of PDE5 which also include a wide range of other erectile medicines, such as sildenafil, …
2,680 results