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94 results

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Page 1
Efinaconazole and Tavaborole.
Poulakos M, Grace Y, Machin JD, Dorval E. Poulakos M, et al. J Pharm Pract. 2017 Apr;30(2):245-255. doi: 10.1177/0897190016630904. Epub 2016 Jul 8. J Pharm Pract. 2017. PMID: 26873506 Review.
PURPOSE: The purpose of this article is to review the safety, efficacy, and role of efinaconazole and tavaborole in the treatment of onychomycosis. SUMMARY: Onychomycosis is a fungal infection of the nail caused by dermatophytes, yeasts, and nondermatophyte fungi. ...The o …
PURPOSE: The purpose of this article is to review the safety, efficacy, and role of efinaconazole and tavaborole in the treatment of …
Spotlight on tavaborole for the treatment of onychomycosis.
Jinna S, Finch J. Jinna S, et al. Drug Des Devel Ther. 2015 Nov 20;9:6185-90. doi: 10.2147/DDDT.S81944. eCollection 2015. Drug Des Devel Ther. 2015. PMID: 26640371 Free PMC article. Review.
Tavaborole is a novel, boron-based anti-fungal agent with greater nail plate penetration than its predecessors, due to its smaller molecular weight. ...In this paper, we review the landscape of topical and systemic treatment of onychomycosis, with particular attention to t
Tavaborole is a novel, boron-based anti-fungal agent with greater nail plate penetration than its predecessors, due to its smaller mo
Tavaborole topical solution, 5% for the treatment of toenail onychomycosis.
Zane LT, Plattner J, Chanda S, Coronado D, Merchant T, Alley MR, Gupta AK. Zane LT, et al. Drugs Today (Barc). 2015 Oct;51(10):599-607. doi: 10.1358/dot.2015.51.10.2401004. Drugs Today (Barc). 2015. PMID: 26583302 Review.
Tavaborole topical solution, 5% (tavaborole) is a novel, boron-based, antifungal pharmaceutical agent indicated for treatment of toenail onychomycosis due to the dermatophytes Trichophyton rubrum or Trichophyton mentagrophytes. ...Results from preclinical studies an
Tavaborole topical solution, 5% (tavaborole) is a novel, boron-based, antifungal pharmaceutical agent indicated for treatment
Tavaborole for the treatment of onychomycosis.
Elewski BE, Tosti A. Elewski BE, et al. Expert Opin Pharmacother. 2014 Jul;15(10):1439-48. doi: 10.1517/14656566.2014.921158. Epub 2014 May 26. Expert Opin Pharmacother. 2014. PMID: 24856836
In vitro and ex vivo studies have demonstrated the superior nail-penetrating properties of tavaborole compared to existing topical antifungal medications approved for the treatment of onychomycosis. AREAS COVERED: The clinical characteristics and prevalence of onychomycosi …
In vitro and ex vivo studies have demonstrated the superior nail-penetrating properties of tavaborole compared to existing topical an …
Tavaborole (AN-2690) for the treatment of onychomycosis of the toenail in adults.
Gupta AK, Daigle D. Gupta AK, et al. Expert Rev Anti Infect Ther. 2014 Jul;12(7):735-42. doi: 10.1586/14787210.2014.915738. Epub 2014 Jun 4. Expert Rev Anti Infect Ther. 2014. PMID: 24894552 Review.
Tavaborole has a unique mechanism of action against fungal organisms and retains antifungal properties in the presence of keratin. Tavaborole 5.0% nail solution has shown a favourable safety and efficacy profile in Phase II/III clinical trials and is currently under
Tavaborole has a unique mechanism of action against fungal organisms and retains antifungal properties in the presence of keratin.
Tavaborole - a treatment for onychomycosis of the toenails.
Gupta AK, Versteeg SG. Gupta AK, et al. Expert Rev Clin Pharmacol. 2016 Sep;9(9):1145-52. doi: 10.1080/17512433.2016.1206467. Epub 2016 Jul 14. Expert Rev Clin Pharmacol. 2016. PMID: 27347905 Review.
Tavaborole (5%) is FDA approved for treating toenail onychomycosis and has shown antifungal activities against yeast, moulds and dermatophytes. ...Tavaborole may be paired with other therapies to potentially increase cure rates....
Tavaborole (5%) is FDA approved for treating toenail onychomycosis and has shown antifungal activities against yeast, moulds and derm
Tavaborole 5% Solution: A Novel Topical Treatment for Toenail Onychomycosis.
Gupta G, Foley KA, Gupta AK. Gupta G, et al. Skin Therapy Lett. 2015 Nov;20(6):6-9. Skin Therapy Lett. 2015. PMID: 27224843 Free article. Review.
As the first antifungal in a boron-containing class of drugs with a novel mechanism of action, tavaborole is able to penetrate the nail plate more effectively than ciclopirox and amorolfine lacquers. In Phase II/III clinical trials, tavaborole was shown to be safe a …
As the first antifungal in a boron-containing class of drugs with a novel mechanism of action, tavaborole is able to penetrate the na …
5-Trifluoromethyl-2-formylphenylboronic Acid.
Adamczyk-Woźniak A, Gozdalik JT, Wieczorek D, Madura ID, Kaczorowska E, Brzezińska E, Sporzyński A, Lipok J. Adamczyk-Woźniak A, et al. Molecules. 2020 Feb 12;25(4):799. doi: 10.3390/molecules25040799. Molecules. 2020. PMID: 32059517 Free PMC article.
It showed possible binding of the cyclic isomer into the binding pocket of Candida albicans LeuRS, similar to that of the recently approved benzoxaborole antifungal drug (AN2690, Tavaborole, Kerydin). In case of Escherichia coli LeuRS, the opened isomer displays a much hig …
It showed possible binding of the cyclic isomer into the binding pocket of Candida albicans LeuRS, similar to that of the recently approved …
Treatment of onychomycosis.
[No authors listed] [No authors listed] Med Lett Drugs Ther. 2021 Oct 18;63(1635):164-168. Med Lett Drugs Ther. 2021. PMID: 35050243 No abstract available.
94 results