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294 results

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Page 1
Efficacy of oral terbinafine versus itraconazole in treatment of dermatophytic infection of skin - A prospective, randomized comparative study.
Bhatia A, Kanish B, Badyal DK, Kate P, Choudhary S. Bhatia A, et al. Indian J Pharmacol. 2019 Mar-Apr;51(2):116-119. doi: 10.4103/ijp.IJP_578_17. Indian J Pharmacol. 2019. PMID: 31142947 Free PMC article. Clinical Trial.
OBJECTIVES: Dermatophytic infections are the common fungal infections aggravated by hot and humid climate. Terbinafine and itraconazole are commonly used oral antifungal agents for the same. However, resistance to these drugs is being seen increasingly when used in the con …
OBJECTIVES: Dermatophytic infections are the common fungal infections aggravated by hot and humid climate. Terbinafine and itraconazo …
Efficacy and safety of Majoon Ushba oral and Marham Raal topical in tinea corporis - A randomized open-labeled active-controlled clinical trial.
Ahmad M, Mobeen A. Ahmad M, et al. Explore (NY). 2023 Sep-Oct;19(5):681-688. doi: 10.1016/j.explore.2023.01.005. Epub 2023 Jan 25. Explore (NY). 2023. PMID: 36740535 Clinical Trial.
Patients were randomly assigned via a computer-generated list to the test group (n=21) receiving oral MU (6 gm) with topical MR and the control group (n=21) topical terbinafine hydrochloride (1%) for 40 days. The severity scores of clinical symptoms; erythema, scaling, itc …
Patients were randomly assigned via a computer-generated list to the test group (n=21) receiving oral MU (6 gm) with topical MR and the cont …
Clinical and pharmacokinetic investigations of oral terbinafine in patients with tinea unguium.
Matsumoto T, Tanuma H, Kaneko S, Takasu H, Nishiyama S. Matsumoto T, et al. Mycoses. 1995 Mar-Apr;38(3-4):135-44. doi: 10.1111/j.1439-0507.1995.tb00037.x. Mycoses. 1995. PMID: 7477090 Clinical Trial.
A pharmacokinetic study revealed that terbinafine was detected in the nail tissue at and after week 2. It reached 0.78 ng mg-1 at the end of week 12 and remained at almost the same level thereafter. Terbinafine was also detected in hair at and after week 23. The ave …
A pharmacokinetic study revealed that terbinafine was detected in the nail tissue at and after week 2. It reached 0.78 ng mg-1 at the …
Clinical efficacy and safety of oral terbinafine in fungal mycetoma.
N'diaye B, Dieng MT, Perez A, Stockmeyer M, Bakshi R. N'diaye B, et al. Int J Dermatol. 2006 Feb;45(2):154-7. doi: 10.1111/j.1365-4632.2004.02392.x. Int J Dermatol. 2006. PMID: 16445509 Clinical Trial.
OBJECTIVES: An open-label study was performed to assess the efficacy and safety of terbinafine in the treatment of eumycetoma. METHODS: Single-center, open-label study, including 27 patients with signs and symptoms of eumycetoma which had developed within 5 years and was c …
OBJECTIVES: An open-label study was performed to assess the efficacy and safety of terbinafine in the treatment of eumycetoma. METHOD …
Results from a Phase 1/2 trial of BB2603, a terbinafine-based topical nano-formulation, in onychomycosis and tinea pedis.
Fuhr R, Cook D, Ridden J, Nield K, Leigh E, Cook J, Davies-Strickleton H, Dobmeyer J. Fuhr R, et al. Mycoses. 2022 Jun;65(6):661-669. doi: 10.1111/myc.13448. Epub 2022 May 20. Mycoses. 2022. PMID: 35466481 Clinical Trial.
BB2603 is a nano-formulation of the antifungal drug terbinafine with the polymer polyhexamethylene biguanide (PHMB) as an excipient to enhance solubility and drug delivery to skin and nails. ...The pharmacokinetic, safety and efficacy data from this trial support further d …
BB2603 is a nano-formulation of the antifungal drug terbinafine with the polymer polyhexamethylene biguanide (PHMB) as an excipient t …
Treatment of tinea imbricata: a randomized clinical trial using griseofulvin, terbinafine, itraconazole and fluconazole.
Wingfield AB, Fernandez-Obregon AC, Wignall FS, Greer DL. Wingfield AB, et al. Br J Dermatol. 2004 Jan;150(1):119-26. doi: 10.1111/j.1365-2133.2004.05643.x. Br J Dermatol. 2004. PMID: 14746625 Clinical Trial.
OBJECTIVES: The aim of this study was to compare the efficacy of itraconazole, terbinafine and fluconazole with that of griseofulvin after 4 weeks of therapy. METHODS: Patients aged 12-76 years with the clinical diagnosis of TI were randomly assigned to one of four treatme …
OBJECTIVES: The aim of this study was to compare the efficacy of itraconazole, terbinafine and fluconazole with that of griseofulvin …
Clinical trial: the safety of terbinafine in patients over the age of 60 years: a multicenter trial in onychomycosis of the feet.
Smith EB, Stein LF, Fivenson DP, Atillasoy ES. Smith EB, et al. Int J Dermatol. 2000 Nov;39(11):861-4. doi: 10.1046/j.1365-4362.2000.00087-2.x. Int J Dermatol. 2000. PMID: 11123452 Clinical Trial.
Following baseline evaluations, eligible patients received a 12-week supply of oral terbinafine (250 mg/day) for self-administration. Compliance was assessed by tablet counts at each visit and defined as the use of at least 80% of the medication prescribed at the first two …
Following baseline evaluations, eligible patients received a 12-week supply of oral terbinafine (250 mg/day) for self-administration. …
Limited effectiveness of four oral antifungal drugs (fluconazole, griseofulvin, itraconazole and terbinafine) in the current epidemic of altered dermatophytosis in India: results of a randomized pragmatic trial.
Singh S, Chandra U, Anchan VN, Verma P, Tilak R. Singh S, et al. Br J Dermatol. 2020 Nov;183(5):840-846. doi: 10.1111/bjd.19146. Epub 2020 Jun 15. Br J Dermatol. 2020. PMID: 32538466 Clinical Trial.

At 8 weeks, the numbers of patients cured were as follows: fluconazole 21 (42%), griseofulvin seven (14%), itraconazole 33 (66%) and terbinafine 14 (28%) (P < 0.001). Itraconazole was superior to fluconazole, griseofulvin and terbinafine (adjusted P 0.048). ...In

At 8 weeks, the numbers of patients cured were as follows: fluconazole 21 (42%), griseofulvin seven (14%), itraconazole 33 (66%) and terb
A comparative clinical and mycological study of Nd-YAG laser versus topical terbinafine in the treatment of onychomycosis.
El-Tatawy RA, Abd El-Naby NM, El-Hawary EE, Talaat RA. El-Tatawy RA, et al. J Dermatolog Treat. 2015 Oct;26(5):461-4. doi: 10.3109/09546634.2014.998607. Epub 2015 Feb 11. J Dermatolog Treat. 2015. PMID: 25669435 Free article. Clinical Trial.
Aim of this work: To compare the clinical and mycological efficacy of Nd-YAG laser versus topical terbinafine in the treatment of onychomycosis. PATIENTS AND METHODS: This study included 40 patients with onychomycosis randomized to receive four sessions of Nd-YAG laser (gr …
Aim of this work: To compare the clinical and mycological efficacy of Nd-YAG laser versus topical terbinafine in the treatment of ony …
A randomized placebo-controlled trial of the efficacy and safety of a terbinafine, florfenicol and betamethasone topical ear formulation in dogs for the treatment of bacterial and/or fungal otitis externa.
Forster SL, Real T, Doucette KP, King SB. Forster SL, et al. BMC Vet Res. 2018 Aug 31;14(1):262. doi: 10.1186/s12917-018-1589-7. BMC Vet Res. 2018. PMID: 30170597 Free PMC article. Clinical Trial.
This study is to report the results of a randomized, placebo-controlled field trial evaluating the efficacy and safety of OSURNIA (Elanco Animal Health, a division of Eli Lilly and Company, Greenfield, IN), a novel topical ear medication containing florfenicol, terbinafine
This study is to report the results of a randomized, placebo-controlled field trial evaluating the efficacy and safety of OSURNIA (Elanco An …
294 results