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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 10
1966 6
1967 13
1968 6
1969 13
1970 14
1971 19
1972 16
1973 29
1974 13
1975 17
1976 27
1977 26
1978 37
1979 51
1980 45
1981 56
1982 53
1983 70
1984 63
1985 76
1986 94
1987 91
1988 94
1989 105
1990 66
1991 76
1992 69
1993 72
1994 74
1995 81
1996 66
1997 63
1998 66
1999 60
2000 53
2001 40
2002 31
2003 34
2004 34
2005 34
2006 43
2007 33
2008 31
2009 21
2010 24
2011 16
2012 23
2013 23
2014 15
2015 13
2016 21
2017 15
2018 8
2019 9
2020 6
2021 14
2022 14
2023 5
2024 8
2025 5
2026 3

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2,254 results

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Page 1
Clinafloxacin-theophylline drug interaction.
Matuschka PR, Vissing RS. Matuschka PR, et al. Ann Pharmacother. 1995 Apr;29(4):378-80. doi: 10.1177/106002809502900407. Ann Pharmacother. 1995. PMID: 7633015 Clinical Trial.
Admission medications included extended-release theophylline 400 mg bid. The initial serum theophylline concentration was 81.03 mumol/L (normal 55-110). ...DISCUSSION: The fluoroquinolones have been shown to interact with the hepatic metabolism of theophylline …
Admission medications included extended-release theophylline 400 mg bid. The initial serum theophylline concentration was 81.0 …
Theophylline and mucociliary clearance.
Ziment I. Ziment I. Chest. 1987 Jul;92(1 Suppl):38S-43S. doi: 10.1378/chest.92.1_supplement.38s. Chest. 1987. PMID: 3297526 Review.
Abnormal mucociliary transport is improvement by the action of theophylline, and this effect can be attributed to several mechanisms. The drug may directly and indirectly mediate the increase in the secretory output of bronchial glands, and this effect is enhanced by the v …
Abnormal mucociliary transport is improvement by the action of theophylline, and this effect can be attributed to several mechanisms. …
Furosemide and theophylline.
Carpentiere G, Marino S, Castello F. Carpentiere G, et al. Ann Intern Med. 1985 Dec;103(6 ( Pt 1)):957. doi: 10.7326/0003-4819-103-6-957_2. Ann Intern Med. 1985. PMID: 4062102 Clinical Trial. No abstract available.
Interaction of ephedrine and theophylline.
Weinberger M, Bronsky E, Bensch GW, Bock GN, Yecies JJ. Weinberger M, et al. Clin Pharmacol Ther. 1975 May;17(5):585-92. doi: 10.1002/cpt1975175585. Clin Pharmacol Ther. 1975. PMID: 1092514 Clinical Trial.
Theophylline, determined by prior clinical titration in each patient, averaged 7.3 mg/kg per dose administered every 6 hr, with peak serum theophylline concentrations averaging about 16 mug/ml. ...Since the combinations were not significantly more effective than …
Theophylline, determined by prior clinical titration in each patient, averaged 7.3 mg/kg per dose administered every 6 hr, with peak …
Salivary theophylline monitoring: reassessment and clinical considerations.
Kirk JK, Dupuis RE, Miles MV, Gaddy GD, Miranda-Massari JR, Williams DM. Kirk JK, et al. Ther Drug Monit. 1994 Feb;16(1):58-66. doi: 10.1097/00007691-199402000-00010. Ther Drug Monit. 1994. PMID: 8160257 Clinical Trial.
To assess the reliability of salivary theophylline concentrations for patient monitoring, concentrations of theophylline in sera and saliva of 50 patients (ages 6-81 years) receiving oral or parenteral theophylline were determined by two methods: a rapid dry- …
To assess the reliability of salivary theophylline concentrations for patient monitoring, concentrations of theophylline in se …
Theophylline Acetaldehyde as the Initial Product in Doxophylline Metabolism in Human Liver.
Zhao X, Ma H, Pan Q, Wang H, Qian X, Song P, Zou L, Mao M, Xia S, Ge G, Yang L. Zhao X, et al. Drug Metab Dispos. 2020 May;48(5):345-352. doi: 10.1124/dmd.119.089565. Epub 2020 Feb 21. Drug Metab Dispos. 2020. PMID: 32086296 Clinical Trial.
Doxophylline (DOXO) and theophylline are widely used as bronchodilators for treating asthma and chronic obstructive pulmonary disease, and DOXO has a better safety profile than theophylline. ...Among them, six metabolites were reported for the first time. The top th …
Doxophylline (DOXO) and theophylline are widely used as bronchodilators for treating asthma and chronic obstructive pulmonary disease …
Clinical and pharmacokinetic evaluation of a sustained-release liquid theophylline preparation.
Guill MF, Pruitt AW, Altman RE, Lawless TE, Brown DA, DuRant RH, Bottini PB. Guill MF, et al. J Allergy Clin Immunol. 1988 Aug;82(2):281-6. doi: 10.1016/0091-6749(88)91012-3. J Allergy Clin Immunol. 1988. PMID: 3403868 Clinical Trial.
Indexes of theophylline fluctuation during the dosing interval indicated equivalent or reduced variability for the suspension. Relative bioavailability of theophylline suspension was 89% of that for the solution.(ABSTRACT TRUNCATED AT 250 WORDS)...
Indexes of theophylline fluctuation during the dosing interval indicated equivalent or reduced variability for the suspension. Relati …
Pharmacokinetics and bioavailability of theophylline following enema and suppository administration in man.
Cole ML, Kunka RL. Cole ML, et al. Biopharm Drug Dispos. 1984 Jul-Sep;5(3):229-40. doi: 10.1002/bdd.2510050305. Biopharm Drug Dispos. 1984. PMID: 6548392 Clinical Trial.
The pharmacokinetics and bioavailability of theophylline from a commercial oral elixir of theophylline, a rectal suppository of aminophylline, and a rectal enema of theophylline monoethanolamine was compared in six normal subjects. ...A rate-limiting, concent …
The pharmacokinetics and bioavailability of theophylline from a commercial oral elixir of theophylline, a rectal suppository o …
In vitro and in vivo sustained-release characteristics of theophylline matrix tablets and novel cluster tablets.
Hayashi T, Kanbe H, Okada M, Kawase I, Ikeda Y, Onuki Y, Kaneko T, Sonobe T. Hayashi T, et al. Int J Pharm. 2007 Aug 16;341(1-2):105-13. doi: 10.1016/j.ijpharm.2007.03.048. Epub 2007 Apr 5. Int J Pharm. 2007. PMID: 17512147 Clinical Trial.
After administration of Tablets A and B containing theophylline at 200mg to fasted dogs, we compared plasma level profiles of theophylline. The mean plasma level of theophylline gradually increased to a maximum (7.17microg/mL) 4h after administration of Table …
After administration of Tablets A and B containing theophylline at 200mg to fasted dogs, we compared plasma level profiles of theo …
Bioequivalence of immediate-release theophylline capsules.
Meyer MC, Jarvi EJ, Straughn AB, Pelsor FR, Williams RL, Shah VP. Meyer MC, et al. Biopharm Drug Dispos. 1999 Dec;20(9):417-9. doi: 10.1002/1099-081x(199912)20:9<417::aid-bdd205>3.0.co;2-w. Biopharm Drug Dispos. 1999. PMID: 10951430 Clinical Trial.
A three-way crossover study in 18 healthy male volunteers was conducted to evaluate the bioequivalence of three different 200 mg anhydrous theophylline immediate-release (IR) capsules. The products had not been rated as therapeutically equivalent by the US Food and …
A three-way crossover study in 18 healthy male volunteers was conducted to evaluate the bioequivalence of three different 200 mg anhydrou …
2,254 results