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1983 10
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Cytotoxic mechanism of tioconazole involves cell cycle arrest at mitosis through inhibition of microtubule assembly.
Sebastian J, Rathinasamy K. Sebastian J, et al. Cytotechnology. 2022 Feb;74(1):141-162. doi: 10.1007/s10616-021-00516-w. Epub 2022 Jan 28. Cytotechnology. 2022. PMID: 35185291 Free PMC article.
Tioconazole is one of the drugs used to treat topical mycotic infections. ...Our study indicates that the systemic adverse effects of tioconazole are partly due to its effects on microtubules and cell cycle arrest. ...
Tioconazole is one of the drugs used to treat topical mycotic infections. ...Our study indicates that the systemic adverse
Fractional carbon dioxide laser and topical tioconazole in the treatment of fingernail onychomycosis.
El-Tatawy RA, Aliweh HA, Hegab DS, Talaat RAZ, Shams Eldeen MA. El-Tatawy RA, et al. Lasers Med Sci. 2019 Dec;34(9):1873-1880. doi: 10.1007/s10103-019-02789-2. Epub 2019 Apr 25. Lasers Med Sci. 2019. PMID: 31025207
Onychomycosis is a common chronic-resistant nail disease. Traditional treatment has its limitations and side effects. This study aimed to evaluate the role of fractional CO(2) laser and topical tioconazole 28% nail lacquer in the treatment of fingernail onychomycosi …
Onychomycosis is a common chronic-resistant nail disease. Traditional treatment has its limitations and side effects. This study aime …
Single-dose tioconazole compared with 3-day clotrimazole treatment in vulvovaginal candidiasis.
Stein GE, Gurwith D, Mummaw N, Gurwith M. Stein GE, et al. Antimicrob Agents Chemother. 1986 Jun;29(6):969-71. doi: 10.1128/AAC.29.6.969. Antimicrob Agents Chemother. 1986. PMID: 3524439 Free PMC article. Clinical Trial.
Of the 32 evaluable patients treated with tioconazole, 27 (84%) remained asymptomatic 4 weeks posttreatment, compared with 28 of 33 patients (85%) treated with clotrimazole. ...Single-dose tioconazole ointment was as effective as a 3-day course of clotrimazole table …
Of the 32 evaluable patients treated with tioconazole, 27 (84%) remained asymptomatic 4 weeks posttreatment, compared with 28 of 33 p …
Contact allergy to tioconazole.
Stubb S, Heikkilä H, Reitamo S, Förström L. Stubb S, et al. Contact Dermatitis. 1992 Mar;26(3):155-8. doi: 10.1111/j.1600-0536.1992.tb00285.x. Contact Dermatitis. 1992. PMID: 1387056
In 15 months, we detected allergic patch test reactions to tioconazole in 14 patients. 9 of the 14 patients were allergic to additional imidazole derivatives used as antifungal agents. ...The abundant use of tioconazole in concentrated (up to 28%) topical formulatio …
In 15 months, we detected allergic patch test reactions to tioconazole in 14 patients. 9 of the 14 patients were allergic to addition …
Contact dermatitis from tioconazole.
Brunelli D, Vincenzi C, Morelli R, Tosti A. Brunelli D, et al. Contact Dermatitis. 1992 Aug;27(2):120. doi: 10.1111/j.1600-0536.1992.tb05228.x. Contact Dermatitis. 1992. PMID: 1395619 No abstract available.
Is tioconazole contact dermatitis still a concern? Bringing allergic contact dermatitis caused by topical tioconazole back into the spotlight.
Pérez-Mesonero R, Schneller-Pavelescu L, Ochando-Ibernón G, Vergara-Sánchez A, Sánchez-Herreros C, Martín-Alcalde E, Gatica-Ortega ME, Silvestre-Salvador JF, Pastor-Nieto MA. Pérez-Mesonero R, et al. Contact Dermatitis. 2019 Mar;80(3):168-169. doi: 10.1111/cod.13146. Epub 2018 Nov 8. Contact Dermatitis. 2019. PMID: 30411354 No abstract available.
The effects of CO(2) laser and topical agent combination therapy for onychomycosis: A meta-analysis.
Han Y, Wang Y, Zhang XR, Chen J, Li XD. Han Y, et al. Dermatol Ther. 2021 Nov;34(6):e15136. doi: 10.1111/dth.15136. Epub 2021 Oct 3. Dermatol Ther. 2021. PMID: 34538013 Review.
The routine options for onychomycosis are oral, topical, and device-based therapies which are often limited in terms of efficacy and unsatisfactory side effects. Topical agents such as luliconazole, tioconazole, terbinafine, and tazarotene can be more effective when …
The routine options for onychomycosis are oral, topical, and device-based therapies which are often limited in terms of efficacy and unsatis …
Comparative and non-comparative studies of the efficacy and tolerance of tioconazole cream 1% versus another imidazole and/or placebo in neonates and infants with candidal diaper rash and/or impetigo.
Gibbs DL, Kashin P, Jevons S. Gibbs DL, et al. J Int Med Res. 1987 Jan-Feb;15(1):23-31. doi: 10.1177/030006058701500103. J Int Med Res. 1987. PMID: 3817280 Clinical Trial.
Side-effects were coincident with disease symptoms and consisted primarily of erythema localized to the treatment area; they occurred in 5.4% (13/241) of the patients who received tioconazole and in 21% (9/43) of the patients who received comparative imidazole (econ …
Side-effects were coincident with disease symptoms and consisted primarily of erythema localized to the treatment area; they occurred …
47 results