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Botulinum neurotoxin versus tizanidine in upper limb spasticity: a placebo-controlled study.
Simpson DM, Gracies JM, Yablon SA, Barbano R, Brashear A; BoNT/TZD Study Team. Simpson DM, et al. J Neurol Neurosurg Psychiatry. 2009 Apr;80(4):380-5. doi: 10.1136/jnnp.2008.159657. Epub 2008 Oct 31. J Neurol Neurosurg Psychiatry. 2009. PMID: 18977811 Clinical Trial.
METHODS: This study performed a randomised, double-blind, placebo-controlled trial to compare injection of BoNT-Type A into spastic upper limb muscles versus oral tizanidine (TZD), or placebo, in 60 subjects with upper-limb spasticity due to stroke or traumatic brain injur …
METHODS: This study performed a randomised, double-blind, placebo-controlled trial to compare injection of BoNT-Type A into spastic upper li …
A Case Report: Tizanidine-Induced Cardiogenic Shock Managed in a U.S. Army Role 3 Field Hospital.
Hutto WM, Jones JH, Ortiz E, Davison KT, Sjulin TJ. Hutto WM, et al. Mil Med. 2026 Jun 30:usag284. doi: 10.1093/milmed/usag284. Online ahead of print. Mil Med. 2026. PMID: 42378494
We report a 58-year-old Active-Duty male who developed transient, severe left ventricular dysfunction with cardiogenic shock after tizanidine ingestion, successfully managed in a forward-deployed Role 3 U.S. Army Field Hospital. ...This case demonstrates that advanced, phy …
We report a 58-year-old Active-Duty male who developed transient, severe left ventricular dysfunction with cardiogenic shock after tizani …