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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 1
1981 4
1982 2
1984 1
1986 1
1987 2
1988 6
1989 2
1991 1
1992 2
1993 1
1994 6
1995 3
1996 3
1997 3
1999 4
2000 1
2001 3
2002 4
2004 5
2005 3
2006 5
2007 6
2008 8
2009 4
2010 3
2011 2
2012 5
2013 4
2014 10
2015 2
2016 2
2017 1
2018 2
2019 1
2020 2
2021 1
2024 0

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109 results

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Page 1
Effect of cold application and tizanidine on clonus: clinical and electrophysiological assessment.
Boyraz I, Oktay F, Celik C, Akyuz M, Uysal H. Boyraz I, et al. J Spinal Cord Med. 2009;32(2):132-9. doi: 10.1080/10790268.2009.11760764. J Spinal Cord Med. 2009. PMID: 19569460 Free PMC article. Clinical Trial.
METHODS: The 38 patients were divided into 3 groups: cold group (n=19), tizanidine group (n=13), and patient control group (n=6). A separate group of 21 able-bodied volunteers served as controls for the cold group. ...Tizanidine had no significant effect on clonus. …
METHODS: The 38 patients were divided into 3 groups: cold group (n=19), tizanidine group (n=13), and patient control group (n=6). A s …
Nightly sublingual tizanidine HCl in multiple sclerosis: clinical efficacy and safety.
Vakhapova V, Auriel E, Karni A. Vakhapova V, et al. Clin Neuropharmacol. 2010 May;33(3):151-4. doi: 10.1097/WNF.0b013e3181daad7d. Clin Neuropharmacol. 2010. PMID: 20502134 Clinical Trial.
Enrolled patients received placebo once nightly and were then randomized to receive oral tizanidine HCl following sublingual tizanidine HCl or sublingual tizanidine HCl following oral tizanidine HCl, each arm for 7 days. ...There were significant reduc …
Enrolled patients received placebo once nightly and were then randomized to receive oral tizanidine HCl following sublingual tizan
Patient education and self-care for the management of jaw pain upon awakening: a randomized controlled clinical trial comparing the effectiveness of adding pharmacologic treatment with cyclobenzaprine or tizanidine.
Alencar FG Jr, Viana PG, Zamperini C, Becker A. Alencar FG Jr, et al. J Oral Facial Pain Headache. 2014 Spring;28(2):119-27. doi: 10.11607/ofph.963. J Oral Facial Pain Headache. 2014. PMID: 24822235 Clinical Trial.
AIMS: To compare the effectiveness of adding cyclobenzaprine, tizanidine, or placebo to patient education and a self-care management program for patients with myofascial pain and specifically presenting with jaw pain upon awakening. ...However, no significant differences a …
AIMS: To compare the effectiveness of adding cyclobenzaprine, tizanidine, or placebo to patient education and a self-care management …
A double-blind comparative trial of new muscle relaxant, tizanidine (DS 103-282), and baclofen in the treatment of chronic spasticity in multiple sclerosis.
Smolenski C, Muff S, Smolenski-Kautz S. Smolenski C, et al. Curr Med Res Opin. 1981;7(6):374-83. Curr Med Res Opin. 1981. PMID: 7016449 Clinical Trial.
Twenty-one hospitalized patients with stable spasticity participated in the 6-week trial. Eleven received tizanidine and 10 baclofen in gradually increasing daily doses. The optimal daily dose of tizanidine was between 8 and 36 mg and that of baclofen between 10 and …
Twenty-one hospitalized patients with stable spasticity participated in the 6-week trial. Eleven received tizanidine and 10 baclofen …
Tizanidine (DS 103-282) in the treatment of acute paravertebral muscle spasm: a controlled trial comparing tizanidine and diazepam.
Fryda-Kaurimsky Z, Müller-Fassbender H. Fryda-Kaurimsky Z, et al. J Int Med Res. 1981;9(6):501-5. doi: 10.1177/030006058100900613. J Int Med Res. 1981. PMID: 6459256 Clinical Trial.
All the patients had suffered from degenerative spinal disease for some years. Ten patients received tizanidine and the other ten received diazepam. Both drugs were administered t.i.d. for a period of 7 days. ...Like diazepam, tizanidine is a suitable drug for the t …
All the patients had suffered from degenerative spinal disease for some years. Ten patients received tizanidine and the other ten rec …
Tizanidine treatment of spasticity caused by multiple sclerosis: results of a double-blind, placebo-controlled trial. US Tizanidine Study Group.
Smith C, Birnbaum G, Carter JL, Greenstein J, Lublin FD. Smith C, et al. Neurology. 1994 Nov;44(11 Suppl 9):S34-42; discussion S42-3. Neurology. 1994. PMID: 7970009 Clinical Trial.
This multicenter, stratified, randomized, placebo-controlled, double-blind trial evaluated tizanidine for use in the United States for spasticity secondary to MS. ...Adverse events were reported for 66 (61%) of the 109 placebo-treated patients and 101 (91%) of the 111 t
This multicenter, stratified, randomized, placebo-controlled, double-blind trial evaluated tizanidine for use in the United States fo …
Effects of gender and moderate smoking on the pharmacokinetics and effects of the CYP1A2 substrate tizanidine.
Backman JT, Schröder MT, Neuvonen PJ. Backman JT, et al. Eur J Clin Pharmacol. 2008 Jan;64(1):17-24. doi: 10.1007/s00228-007-0389-y. Epub 2007 Oct 23. Eur J Clin Pharmacol. 2008. PMID: 17955229 Clinical Trial.
OBJECTIVE: We studied the effects of gender and smoking on the pharmacokinetics and effects of the cytochrome P450 (CYP) 1A2 substrate tizanidine. METHODS: Seventy-one healthy young volunteers (male and female nonsmokers, male smokers) ingested 4 mg tizanidine. ...C …
OBJECTIVE: We studied the effects of gender and smoking on the pharmacokinetics and effects of the cytochrome P450 (CYP) 1A2 substrate ti
Tizanidine in the treatment of spasticity.
Newman PM, Nogues M, Newman PK, Weightman D, Hudgson P. Newman PM, et al. Eur J Clin Pharmacol. 1982;23(1):31-5. doi: 10.1007/BF01061374. Eur J Clin Pharmacol. 1982. PMID: 6751834 Clinical Trial.
A double-blind crossover trial compared tizanidine with baclofen in 36 patients with spasticity. Tizanidine appeared to reduce lower limb spasticity more effectively and to have fewer side effects, but no statistically significant differences emerged when the two dr …
A double-blind crossover trial compared tizanidine with baclofen in 36 patients with spasticity. Tizanidine appeared to reduce …
The sedative and sympatholytic effects of oral tizanidine in healthy volunteers.
Miettinen TJ, Kanto JH, Salonen MA, Scheinin M. Miettinen TJ, et al. Anesth Analg. 1996 Apr;82(4):817-20. doi: 10.1097/00000539-199604000-00024. Anesth Analg. 1996. PMID: 8615503 Clinical Trial.
Three different doses of tizanidine (4, 8, and 12 mg) were tested and compared to clonidine 150 micrograms. ...Clonidine and tizanidine 12 mg had also similar effects on the secretion of growth hormone. ...
Three different doses of tizanidine (4, 8, and 12 mg) were tested and compared to clonidine 150 micrograms. ...Clonidine and tizan
Cost-effectiveness comparison of tizanidine and baclofen in the management of spasticity.
Rushton DN, Lloyd AC, Anderson PM. Rushton DN, et al. Pharmacoeconomics. 2002;20(12):827-37. doi: 10.2165/00019053-200220120-00003. Pharmacoeconomics. 2002. PMID: 12236804 Clinical Trial.
OBJECTIVE: Baclofen and tizanidine are both used for the treatment of muscle spasticity of spinal origin. ...RESULTS: Expected cost for a cohort of 100 patients over 1 year was estimated to be pound 181 545 with baclofen and pound 211 930 with tizanidine. The estima …
OBJECTIVE: Baclofen and tizanidine are both used for the treatment of muscle spasticity of spinal origin. ...RESULTS: Expected cost f …
109 results