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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1973 4
1974 11
1975 8
1976 8
1977 4
1978 8
1979 8
1980 8
1981 16
1982 14
1983 41
1984 27
1985 35
1986 31
1987 26
1988 20
1989 17
1990 23
1991 22
1992 15
1993 22
1994 19
1995 16
1996 20
1997 24
1998 18
1999 22
2000 11
2001 20
2002 16
2003 6
2004 7
2005 9
2006 16
2007 27
2008 14
2009 15
2010 16
2011 17
2012 21
2013 23
2014 18
2015 11
2016 13
2017 11
2018 7
2019 7
2020 16
2021 6
2022 3
2023 6
2024 4
2025 7
2026 0

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763 results

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Page 1
Aminoglycoside ototoxicity.
Matz GJ. Matz GJ. Am J Otolaryngol. 1986 Mar-Apr;7(2):117-9. doi: 10.1016/s0196-0709(86)80040-0. Am J Otolaryngol. 1986. PMID: 3485932 Clinical Trial.
Amikacin was ototoxic 12.9 per cent of the time, whereas the incidence of tobramycin ototoxicity was 11.5 per cent, and the incidence of netilmicin ototoxicity was 2 per cent. ...Gentamicin, on the other hand, produced a 18.6 per cent, tobramycin a 25 per cent, and …
Amikacin was ototoxic 12.9 per cent of the time, whereas the incidence of tobramycin ototoxicity was 11.5 per cent, and the incidence …
A clinical trial of teicoplanin compared with a combination of flucloxacillin and tobramycin as antibiotic prophylaxis for cardiac surgery: the use of a scoring method to assess the incidence of wound infection.
Wilson AP, Grüneberg RN, Treasure T, Sturridge MF. Wilson AP, et al. J Hosp Infect. 1986 Mar;7 Suppl A:105-12. doi: 10.1016/0195-6701(86)90015-0. J Hosp Infect. 1986. PMID: 2871092 Clinical Trial.
A prospective randomized clinical trial is in progress to compare the efficacy of teicoplanin with flucloxacillin and tobramycin in the prevention of endocarditis and wound infection following cardiac surgery. To date, 198 patients have completed the trial, of whom 95 have …
A prospective randomized clinical trial is in progress to compare the efficacy of teicoplanin with flucloxacillin and tobramycin in t …
A prospective phase IIA multicenter double-blinded randomized placebo-controlled clinical trial evaluating the efficacy and safety of inhaled Tobramycin in patients with ventilator-associated pneumonia (iToVAP).
Angermair S, Deja M, Thronicke A, Grehn C, Akbari N, Uhrig A, Asgarpur G, Spies C, Treskatsch S, Schwarz C. Angermair S, et al. Anaesth Crit Care Pain Med. 2023 Oct;42(5):101249. doi: 10.1016/j.accpm.2023.101249. Epub 2023 May 20. Anaesth Crit Care Pain Med. 2023. PMID: 37217019 Free article. Clinical Trial.
Therefore, we aimed to investigate the efficacy of the adjunctive inhaled Tobramycin in patients with pneumonia caused by Gram-negative pathogens in addition to the standard systemic treatment. ...The increased eradication frequency was not associated with increased patien …
Therefore, we aimed to investigate the efficacy of the adjunctive inhaled Tobramycin in patients with pneumonia caused by Gram-negati …
The role of ozonized oil and a combination of tobramycin/dexamethasone eye drops in the treatment of viral conjunctivitis: a randomized clinical trial.
Cagini C, Mariniello M, Messina M, Muzi A, Balducci C, Moretti A, Levorato L, Mencacci A. Cagini C, et al. Int Ophthalmol. 2020 Dec;40(12):3209-3215. doi: 10.1007/s10792-020-01503-4. Epub 2020 Jul 22. Int Ophthalmol. 2020. PMID: 32696102 Free PMC article. Clinical Trial.
PURPOSE: To determine whether topical tobramycin 0.3%/dexamethasone 0.1% plus ozonized oil eye drops reduces clinical signs and infectious viral titers of presumed viral conjunctivitis more than tobramycin/dexamethasone eye drops alone. ...Patients in the study grou …
PURPOSE: To determine whether topical tobramycin 0.3%/dexamethasone 0.1% plus ozonized oil eye drops reduces clinical signs and infec …
Impact of azithromycin on the clinical and antimicrobial effectiveness of tobramycin in the treatment of cystic fibrosis.
Nichols DP, Happoldt CL, Bratcher PE, Caceres SM, Chmiel JF, Malcolm KC, Saavedra MT, Saiman L, Taylor-Cousar JL, Nick JA. Nichols DP, et al. J Cyst Fibros. 2017 May;16(3):358-366. doi: 10.1016/j.jcf.2016.12.003. Epub 2016 Dec 24. J Cyst Fibros. 2017. PMID: 28025037 Free PMC article. Clinical Trial.
BACKGROUND: Concomitant use of oral azithromycin and inhaled tobramycin occurs in approximately half of US cystic fibrosis (CF) patients. Recent data suggest that this combination may be antagonistic. ...CFQ-R respiratory symptom score decreased 1.8 points during inhaled …
BACKGROUND: Concomitant use of oral azithromycin and inhaled tobramycin occurs in approximately half of US cystic fibrosis (CF) patie …
Comparative clinical pharmacology of gentamicin, sisomicin, and tobramycin.
Lode H, Kemmerich B, Koeppe P. Lode H, et al. Antimicrob Agents Chemother. 1975 Oct;8(4):396-401. doi: 10.1128/AAC.8.4.396. Antimicrob Agents Chemother. 1975. PMID: 1103722 Free PMC article. Clinical Trial.
Using a randomized crossover design involving 12 normal subjects, we studied comparatively the pharmacokinetics and tolerance of three aminoglycoside antibiotics, gentamicin, sisomicin, and tobramycin. Serum concentrations were determined during 8 h and the urine recovery …
Using a randomized crossover design involving 12 normal subjects, we studied comparatively the pharmacokinetics and tolerance of three amino …
Safety Profile of Seven-Day Intra-articular Antibiotic Irrigation for the Treatment of Chronic Periprosthetic Joint Infection: A Prospective Randomized Phase II Comparative Study.
Springer BD, Higuera-Rueda CA, de Beaubien BC, Warner KD, Glassman AH, Parvataneni HK, Piuzzi NS. Springer BD, et al. J Arthroplasty. 2024 Sep;39(9S1):S229-S235.e1. doi: 10.1016/j.arth.2024.03.069. Epub 2024 Apr 9. J Arthroplasty. 2024. PMID: 38604274 Clinical Trial.
The Experimental Group received irrigation using 80 mg tobramycin daily with a 2-hour soak, followed by hourly irrigation using 125 mg vancomycin with a 30-minute soak via an intramedullary irrigation device. The Control Group received an antibiotic-loaded cement spacer wi …
The Experimental Group received irrigation using 80 mg tobramycin daily with a 2-hour soak, followed by hourly irrigation using 125 m …
A multicenter, randomized, parallel-group, clinical trial comparing the safety and efficacy of loteprednol etabonate 0.5%/tobramycin 0.3% with dexamethasone 0.1%/tobramycin 0.3% in the treatment of Chinese patients with blepharokeratoconjunctivitis.
Chen M, Gong L, Sun X, Gu Y, He X, Qu J, Wang L, Zhang M, Zhong X. Chen M, et al. Curr Med Res Opin. 2012 Mar;28(3):385-94. doi: 10.1185/03007995.2012.659723. Epub 2012 Feb 7. Curr Med Res Opin. 2012. PMID: 22256909 Clinical Trial.
OBJECTIVE: To compare the efficacy and safety of loteprednol etabonate 0.5%/tobramycin 0.3% (LE/T) and dexamethasone 0.1%/tobramycin 0.3% (DM/T) ophthalmic suspensions in a Chinese population with ocular inflammation associated with blepharokeratoconjunctivitis (BKC …
OBJECTIVE: To compare the efficacy and safety of loteprednol etabonate 0.5%/tobramycin 0.3% (LE/T) and dexamethasone 0.1%/tobramyc …
Testing the effects of combining azithromycin with inhaled tobramycin for P. aeruginosa in cystic fibrosis: a randomised, controlled clinical trial.
Nichols DP, Singh PK, Baines A, Caverly LJ, Chmiel JF, GIbson RL, Lascano J, Morgan SJ, Retsch-Bogart G, Saiman L, Sadeghi H, Billings JL, Heltshe SL, Kirby S, Kong A, Nick JA, Mayer-Hamblett N; TEACH Study Group. Nichols DP, et al. Thorax. 2022 Jun;77(6):581-588. doi: 10.1136/thoraxjnl-2021-217782. Epub 2021 Oct 27. Thorax. 2022. PMID: 34706982 Free PMC article. Clinical Trial.
RATIONALE: Inhaled tobramycin and oral azithromycin are common chronic therapies in people with cystic fibrosis and Pseudomonas aeruginosa airway infection. Some studies have shown that azithromycin can reduce the ability of tobramycin to kill P. aeruginosa. This tr …
RATIONALE: Inhaled tobramycin and oral azithromycin are common chronic therapies in people with cystic fibrosis and Pseudomonas aerug …
A clinical comparison of tobramycin and gentamicin sulfate in the treatment of ocular infections.
Laibson P, Michaud R, Smolin G, Okumoto M, Rosenthal A, Cagle G. Laibson P, et al. Am J Ophthalmol. 1981 Dec;92(6):836-41. doi: 10.1016/s0002-9394(14)75639-9. Am J Ophthalmol. 1981. PMID: 7032304 Clinical Trial.
We evaluated the safety and efficacy of tobramycin and gentamicin sulfate ophthalmic solutions in the treatment of patients with bacterial infections of the conjunctivas. In this double-masked study involving 66 patients, the two aminoglycosides were found to be equally sa …
We evaluated the safety and efficacy of tobramycin and gentamicin sulfate ophthalmic solutions in the treatment of patients with bact …
763 results