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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1978 6
1980 2
1981 4
1982 2
1984 1
1985 2
1986 2
1987 1
1988 3
1989 4
1990 3
1991 4
1992 14
1993 10
1994 13
1995 8
1996 18
1997 19
1998 29
1999 44
2000 33
2001 36
2002 31
2003 52
2004 57
2005 55
2006 64
2007 70
2008 73
2009 87
2010 70
2011 75
2012 91
2013 80
2014 70
2015 72
2016 63
2017 57
2018 62
2019 64
2020 62
2021 22
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1,399 results
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A pilot clinical trial comparing efficacy and safety of tramadol versus prednisone along with therapeutic ultrasound as adjuvant therapy in Chinese patients with carpal tunnel syndrome diagnosed by ultrasonography.
Han Y, Zhang C, Li K. Han Y, et al. Pak J Pharm Sci. 2020 May;33(3(Special)):1397-1402. Pak J Pharm Sci. 2020. PMID: 33361029 Clinical Trial.
CTS were evaluated before and after treatment through clinical findings, Boston Carpal Tunnel Questionnaire, visual analog scale (VAS) and electrophysiological data. The results were evaluated with Student's t test and chi-squared. A statistically significant difference wa …
CTS were evaluated before and after treatment through clinical findings, Boston Carpal Tunnel Questionnaire, visual analog scale (VAS) and e …
Postoperative Analgesia After Wound Infiltration With Tramadol and Dexmedetomidine as an Adjuvant to Ropivacaine for Lumbar Discectomies: A Randomized-controlled Clinical Trial.
Mitra S, Purohit S, Sharma M. Mitra S, et al. J Neurosurg Anesthesiol. 2017 Oct;29(4):433-438. doi: 10.1097/ANA.0000000000000422. J Neurosurg Anesthesiol. 2017. PMID: 28266950 Clinical Trial.
INTRODUCTION: Crippling postoperative pain linked with lumbar discectomies not only shackles patient's normal daily activities but also lengthens their hospital stay. ...The aim of this trial was to evaluate the analgesic efficacy of tramadol and dexmedetomidine whe …
INTRODUCTION: Crippling postoperative pain linked with lumbar discectomies not only shackles patient's normal daily activities but al …
A comparison of tramadol and pethidine analgesia on the duration of labour: a randomised clinical trial.
Khooshideh M, Shahriari A. Khooshideh M, et al. Aust N Z J Obstet Gynaecol. 2009 Feb;49(1):59-63. doi: 10.1111/j.1479-828X.2009.00949.x. Aust N Z J Obstet Gynaecol. 2009. PMID: 19281581 Clinical Trial.
Group P received 50 mg pethidine; and group T, 100 mg tramadol intramuscularly. Primary outcome measure was the duration of the labour. ...Tramadol seems to cause a shorter duration of labour and lower incidence of maternal side-effects. ...
Group P received 50 mg pethidine; and group T, 100 mg tramadol intramuscularly. Primary outcome measure was the duration of the labou …
Tramadol Does Not Improve Performance or Impair Motor Function in Trained Cyclists.
Bejder J, Breenfeldt Andersen A, Bonne TC, Piil JF, Hagen LCH, Dehnes Y, Eibye KH, Nybo L, Nordsborg NB. Bejder J, et al. Med Sci Sports Exerc. 2020 May;52(5):1169-1175. doi: 10.1249/MSS.0000000000002217. Med Sci Sports Exerc. 2020. PMID: 31809408 Clinical Trial.
RESULTS: Time trial mean power output (298 42 W vs 294 44 W) and performance (1474 77 s vs 1483 85 s) were similar with Tramadol and placebo treatment, respectively. ...None of the combined motor-cognitive tasks were impaired by Tramadol ingestion, in …
RESULTS: Time trial mean power output (298 42 W vs 294 44 W) and performance (1474 77 s vs 1483 85 s) were similar with Tra
Intravenous Tramadol is Effective in the Management of Postoperative Pain Following Abdominoplasty: A Three-Arm Randomized Placebo- and Active-Controlled Trial.
Minkowitz H, Salazar H, Leiman D, Solanki D, Lu L, Reines S, Ryan M, Harnett M, Singla N. Minkowitz H, et al. Drugs R D. 2020 Sep;20(3):225-236. doi: 10.1007/s40268-020-00309-0. Drugs R D. 2020. PMID: 32409981 Free PMC article. Clinical Trial.
The consistency of effects between tramadol and morphine (as compared to placebo) for primary and key secondary endpoints validates the efficacy of tramadol observed. The study also provided direct evidence of improved tolerability of IV tramadol over a stand …
The consistency of effects between tramadol and morphine (as compared to placebo) for primary and key secondary endpoints validates t …
Efficacy and Safety of Two Fixed-Dose Combinations of Tramadol Hydrochloride and Diclofenac Sodium in Postoperative Dental Pain.
Desjardins P, Alvarado F, Gil M, González M, Guajardo R. Desjardins P, et al. Pain Med. 2020 Oct 1;21(10):2447-2457. doi: 10.1093/pm/pnaa124. Pain Med. 2020. PMID: 32488263 Clinical Trial.
OBJECTIVE: To evaluate the analgesic efficacy and safety of tramadol hydrochloride/diclofenac sodium fixed-dose combination 25 mg/25 mg (FDC 25/25) and 50 mg/50 mg (FDC 50/50) vs tramadol 50 mg (T50) and diclofenac 50 mg (D50) monotherapies in acute postoperative de …
OBJECTIVE: To evaluate the analgesic efficacy and safety of tramadol hydrochloride/diclofenac sodium fixed-dose combination 25 mg/25 …
Efficacy and safety of extended-release, once-daily tramadol in chronic pain: a randomized 12-week clinical trial in osteoarthritis of the knee.
Babul N, Noveck R, Chipman H, Roth SH, Gana T, Albert K. Babul N, et al. J Pain Symptom Manage. 2004 Jul;28(1):59-71. doi: 10.1016/j.jpainsymman.2003.11.006. J Pain Symptom Manage. 2004. PMID: 15223085 Free article. Clinical Trial.
The efficacy and safety of a once-daily extended-release formulation of tramadol hydrochloride (tramadol ER) was evaluated in patients with moderate to severe chronic pain of osteoarthritis (OA). ...The mean age was 61 years, mean duration of OA 12.9 years, and the …
The efficacy and safety of a once-daily extended-release formulation of tramadol hydrochloride (tramadol ER) was evaluated in …
Pharmacokinetics of Tramadol and Celecoxib in Japanese and Caucasian Subjects Following Administration of Co-Crystal of Tramadol-Celecoxib (CTC): A Randomised, Open-Label Study.
Dooner H, Mundin G, Mersmann S, Bennett C, Lorch U, Encabo M, Escriche M, Encina G, Smith K. Dooner H, et al. Eur J Drug Metab Pharmacokinet. 2019 Feb;44(1):63-75. doi: 10.1007/s13318-018-0491-9. Eur J Drug Metab Pharmacokinet. 2019. PMID: 29956215 Free PMC article. Clinical Trial.
BACKGROUND AND OBJECTIVES: Co-Crystal of Tramadol-Celecoxib (CTC) is a first-in-class active pharmaceutical ingredient (API-API) co-crystal of rac-tramadol.HCl and celecoxib in a 1:1 molecular ratio (100 mg CTC: 44 mg rac-tramadol.HCl and 56 mg celecoxib). .. …
BACKGROUND AND OBJECTIVES: Co-Crystal of Tramadol-Celecoxib (CTC) is a first-in-class active pharmaceutical ingredient (API-API) co-c …
Tramadol Effects on Lameness Score After Inhibition of P-GP by Ivermectin Administration in Horses: Preliminary Results.
Ferreira da Cruz FS, Natalini CC, Pellin de Molnar BF, Beatriz da Silva Serpa P, Tisotti T, Midon M, Desessards de La Côrte F. Ferreira da Cruz FS, et al. J Equine Vet Sci. 2020 Sep;92:103163. doi: 10.1016/j.jevs.2020.103163. Epub 2020 Jun 24. J Equine Vet Sci. 2020. PMID: 32797786 Clinical Trial.
Six horses were randomly distributed into three groups, which received two different doses of tramadol by a nasogastric tube: 1 mg/kg (tramadol group 1(GT1)), 4 mg/kg (tramadol group 4 (GT4)), and tramadol 1 mg/kg combined with ivermectin 0.2 mg/kg PO …
Six horses were randomly distributed into three groups, which received two different doses of tramadol by a nasogastric tube: 1 mg/kg …
The addition of tramadol to the standard of i.v. acetaminophen and morphine infusion for postoperative analgesia in neonates offers no clinical benefit: a randomized placebo-controlled trial.
Olischar M, Palmer GM, Orsini F, Davidson AJ, Perkins EJ, Lee KJ, Everest NJ, Cranswick NE, Hunt RW. Olischar M, et al. Paediatr Anaesth. 2014 Nov;24(11):1149-57. doi: 10.1111/pan.12477. Epub 2014 Jul 14. Paediatr Anaesth. 2014. PMID: 25040756 Clinical Trial.
OBJECTIVE: This randomized placebo-controlled trial aimed to assess whether tramadol's addition to standard analgesia resulted in earlier extubation or reduced analgesic/sedative requirements in postsurgical neonates. ...This questions the benefit of tramadol
OBJECTIVE: This randomized placebo-controlled trial aimed to assess whether tramadol's addition to standard analgesia resulted …
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