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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 2
1973 8
1974 2
1975 7
1976 12
1977 6
1979 5
1980 8
1981 4
1982 9
1983 5
1984 19
1985 4
1986 12
1987 9
1988 16
1989 16
1990 9
1991 8
1992 5
1993 5
1994 15
1995 3
1996 7
1997 7
1998 2
1999 13
2000 7
2001 3
2002 3
2003 7
2004 7
2005 5
2006 2
2007 8
2008 4
2009 6
2010 4
2011 6
2012 4
2013 6
2014 8
2015 7
2016 4
2017 5
2018 3
2019 3
2020 8
2021 4
2022 3
2023 5
2024 5
2025 6
2026 3

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342 results

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Page 1
Second-generation antidepressants.
Rudorfer MV, Golden RN, Potter WZ. Rudorfer MV, et al. Psychiatr Clin North Am. 1984 Sep;7(3):519-34. Psychiatr Clin North Am. 1984. PMID: 6237317 Review.
Effect of Psychological and Medication Therapies for Insomnia on Daytime Functions: A Randomized Clinical Trial.
Morin CM, Chen SJ, Ivers H, Beaulieu-Bonneau S, Krystal AD, Guay B, Bélanger L, Cartwright A, Simmons B, Lamy M, Busby M, Edinger JD. Morin CM, et al. JAMA Netw Open. 2023 Dec 1;6(12):e2349638. doi: 10.1001/jamanetworkopen.2023.49638. JAMA Netw Open. 2023. PMID: 38153735 Free PMC article. Clinical Trial.
INTERVENTIONS: Participants were randomly assigned to either BT or zolpidem as first-stage therapy, and those whose insomnia had not remitted received a second-stage psychological therapy (BT or cognitive therapy) or medication therapy (zolpidem or trazodone). MAIN OUTCOME …
INTERVENTIONS: Participants were randomly assigned to either BT or zolpidem as first-stage therapy, and those whose insomnia had not remitte …
Trazodone in depression.
Wheatley D. Wheatley D. Int Pharmacopsychiatry. 1980;15(4):240-6. doi: 10.1159/000468443. Int Pharmacopsychiatry. 1980. PMID: 7021449 Clinical Trial.
Dose comparison trials were undertaken with trazodone given once, twice and thrice daily. Therapeutic effects were the same but once daily dosage produced drowsiness whilst thrice daily dosage did not. ...
Dose comparison trials were undertaken with trazodone given once, twice and thrice daily. Therapeutic effects were the same but once …
Antidepressant properties of trazodone.
Bryant SG, Ereshefsky L. Bryant SG, et al. Clin Pharm. 1982 Sep-Oct;1(5):406-17. Clin Pharm. 1982. PMID: 6764164 Review.
Trazodone has few cardiovascular side effects. In patients ingesting toxic amounts of trazodone, no deaths have been reported unless other drugs were present or ingested concomitantly. The usual adult daily dose of trazodone hydrochloride is 150-400 mg given …
Trazodone has few cardiovascular side effects. In patients ingesting toxic amounts of trazodone, no deaths have been reported …
A Randomized Controlled Trial of the Safety and Efficacy of Dronabinol for Agitation in Alzheimer's Disease.
Rosenberg PB, Amjad H, Burhanullah H, Nowrangi M, Vandrey R, Pierre MJ, Outen JD, Schultz M, Marano C, Agronin M, Wilkins JM, Harper D, Laffaye T, Reardon E, Turner K, Ozonsi R, Drury M, Nguyen A, Hasoğlu T, Cromwell J, Leoutsakos JM, Forester BP. Rosenberg PB, et al. Am J Geriatr Psychiatry. 2026 Feb;34(2):167-179. doi: 10.1016/j.jagp.2025.10.011. Epub 2025 Nov 10. Am J Geriatr Psychiatry. 2026. PMID: 41350162 Clinical Trial.
No secondary outcomes differed between treatment arms including sleep, activities of daily living, Cohen-Mansfield Agitation Inventory (CMAI), cognition, intoxication, or use of 'as-needed' lorazepam or trazodone. Dronabinol treatment was not associated with greater intoxi …
No secondary outcomes differed between treatment arms including sleep, activities of daily living, Cohen-Mansfield Agitation Inventory (CMAI …
Tinnitus treatment with Trazodone.
Dib GC, Kasse CA, Alves de Andrade T, Gurgel Testa JR, Cruz OL. Dib GC, et al. Braz J Otorhinolaryngol. 2007 May-Jun;73(3):390-7. doi: 10.1016/s1808-8694(15)30084-7. Braz J Otorhinolaryngol. 2007. PMID: 17684661 Free PMC article. Clinical Trial.
Tinnitus is a common symptom, defined as a sound perception in absence of a sound stimulus. AIM: Evaluate if Trazodone, an antidepressant drug, which modulates serotonin at central neuronal pathways, is effective in controlling tinnitus. ...Patients with age equal or over …
Tinnitus is a common symptom, defined as a sound perception in absence of a sound stimulus. AIM: Evaluate if Trazodone, an antidepres …
Safety and efficacy of memantine and trazodone versus placebo for motor neuron disease (MND SMART): stage two interim analysis from the first cycle of a phase 3, multiarm, multistage, randomised, adaptive platform trial.
Pal S, Chataway J, Swingler R, Macleod MR, Carragher NO, Hardingham G, Selvaraj BT, Smith C, Wong C, Newton J, Lyle D, Stenson A, Dakin RS, Ihenacho A, Colville S, Mehta AR, Stallard N, Carpenter JR, Parker RA, Keerie C, Weir CJ, Virgo B, Morris S, Waters N, Gray B, MacDonald D, MacDonald E, Parmar MKB, Chandran S; MND SMART Investigators. Pal S, et al. Lancet Neurol. 2024 Nov;23(11):1097-1107. doi: 10.1016/S1474-4422(24)00326-0. Epub 2024 Sep 19. Lancet Neurol. 2024. PMID: 39307154 Free article. Clinical Trial.
The one-sided p values were both above the significance threshold of 10%, indicating that neither memantine nor trazodone groups met the criteria for continuation. There were 483 participants with at least one adverse event (145 [77%] on placebo, 170 [91%] on memantine, an …
The one-sided p values were both above the significance threshold of 10%, indicating that neither memantine nor trazodone groups met …
Effectiveness of Existing Insomnia Therapies for Patients Undergoing Hemodialysis : A Randomized Clinical Trial.
Mehrotra R, Cukor D, McCurry SM, Rue T, Roumelioti ME, Heagerty PJ, Unruh M. Mehrotra R, et al. Ann Intern Med. 2024 Feb;177(2):177-188. doi: 10.7326/M23-1794. Epub 2024 Jan 16. Ann Intern Med. 2024. PMID: 38224591 Clinical Trial.
RESULTS: A total of 923 patients were prescreened, and of the 411 patients with chronic insomnia, 126 were randomly assigned to CBT-I (n = 43), trazodone (n = 42), or placebo (n = 41). The change in ISI scores from baseline to 7 weeks with CBT-I or trazodone was no …
RESULTS: A total of 923 patients were prescreened, and of the 411 patients with chronic insomnia, 126 were randomly assigned to CBT-I (n = 4 …
Trazodone-oral cocaine interactions.
Rowbotham MC, Jones RT, Benowitz NL, Jacob P 3rd. Rowbotham MC, et al. Arch Gen Psychiatry. 1984 Sep;41(9):895-9. doi: 10.1001/archpsyc.1984.01790200077010. Arch Gen Psychiatry. 1984. PMID: 6380447 Clinical Trial.
Trazodone alone did not alter plasma epinephrine or norepinephrine levels. An increase in plasma epinephrine levels after cocaine administration was not altered by trazodone pretreatment, but the increase in the norepinephrine level was larger. Trazodone alon …
Trazodone alone did not alter plasma epinephrine or norepinephrine levels. An increase in plasma epinephrine levels after cocaine adm …
Recent experience with trazodone.
Lader M. Lader M. Psychopathology. 1987;20 Suppl 1:39-47. doi: 10.1159/000284522. Psychopathology. 1987. PMID: 3321129 Review.
Trazodone is an atypical antidepressant with additional anxiolytic effects. Recent European experience with trazodone is reviewed with respect to antidepressant efficacy, side effects (particularly anticholinergic), anxiolytic actions, cardiotoxicity, overdosage, an …
Trazodone is an atypical antidepressant with additional anxiolytic effects. Recent European experience with trazodone is revie …
342 results