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Year Number of Results
1966 1
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1974 7
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1976 5
1977 2
1978 2
1979 1
1980 2
1981 1
1982 1
1983 2
1984 3
1985 1
1986 4
1987 7
1988 3
1989 1
1990 2
1991 2
1992 3
1994 2
1995 2
1996 4
1997 2
1998 1
1999 3
2000 1
2001 1
2002 1
2004 1
2007 1
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2026 0

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99 results

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Page 1
Crossover clinical trial of benapryzine and trihexyphenidyl in Parkinsonian patients.
Lamid S, Jenkins RB. Lamid S, et al. J Clin Pharmacol. 1975 Aug-Sep;15(8-9):622-6. doi: 10.1002/j.1552-4604.1975.tb02381.x. J Clin Pharmacol. 1975. PMID: 1097479 Clinical Trial.
A crossover clinical trial of benapryzine and trihexyphenidyl in ten parkinsonian patients during a four-month study is described. The improvement from initial disability ranged from 29.5 to 64.4 per cent for benapryzine and from 27.2 to 64.9 per cent for trihexyphenidy …
A crossover clinical trial of benapryzine and trihexyphenidyl in ten parkinsonian patients during a four-month study is described. Th …
Trihexyphenidyl and torticollis.
Scherokman B, Jabbari B, Gunderson CH, Miller JM, Rappaport HL. Scherokman B, et al. Neurology. 1986 Dec;36(12):1626. doi: 10.1212/wnl.36.12.1626. Neurology. 1986. PMID: 3537844 Clinical Trial. No abstract available.
Comparison of Effectiveness and Tolerability of Clonidine and Trihexyphenidyl in Clozapine-Induced Hypersalivation.
Pansawat P, Pansawat W, Silaket S, Supapaan TS, Boonlue T. Pansawat P, et al. J Clin Psychopharmacol. 2025 Mar-Apr 01;45(2):76-84. doi: 10.1097/JCP.0000000000001968. Epub 2025 Feb 6. J Clin Psychopharmacol. 2025. PMID: 39913268 Clinical Trial.
The objective of the study is to compare the effectiveness and tolerability of (1) trihexyphenidyl 5 mg/d, (2) clonidine 0.15 mg/d, or (3) a reduction of clozapine dosage by 25 to 50 mg/d for managing clozapine-induced hypersalivation. ...IMPLICATIONS/CONCLUSIONS: Clonidin …
The objective of the study is to compare the effectiveness and tolerability of (1) trihexyphenidyl 5 mg/d, (2) clonidine 0.15 mg/d, o …
Withdrawal of trihexyphenidyl.
McInnis M, Petursson H. McInnis M, et al. Acta Psychiatr Scand. 1985 Mar;71(3):297-303. doi: 10.1111/j.1600-0447.1985.tb01287.x. Acta Psychiatr Scand. 1985. PMID: 3984771 Clinical Trial.
In a group of 22 psychiatric patients receiving long-term antipsychotic medication concurrently with trihexyphenidyl the effects of trihexyphenidyl withdrawal were studied double-blind and placebo controlled. ...The majority of the parameters regained baseline value …
In a group of 22 psychiatric patients receiving long-term antipsychotic medication concurrently with trihexyphenidyl the effects of …
Prospective open-label clinical trial of trihexyphenidyl in children with secondary dystonia due to cerebral palsy.
Sanger TD, Bastian A, Brunstrom J, Damiano D, Delgado M, Dure L, Gaebler-Spira D, Hoon A, Mink JW, Sherman-Levine S, Welty LJ; Child Motor Study Group. Sanger TD, et al. J Child Neurol. 2007 May;22(5):530-7. doi: 10.1177/0883073807302601. J Child Neurol. 2007. PMID: 17690057 Clinical Trial.
All children were given trihexyphenidyl at increasing doses over a 9-week period up to a maximum of 0.75 mg/kg/d. Trihexyphenidyl was subsequently tapered off over the next 5 weeks. ...The authors conclude that scientific evidence for the clinical use of trihexyp …
All children were given trihexyphenidyl at increasing doses over a 9-week period up to a maximum of 0.75 mg/kg/d. Trihexyphenidyl …
Efficacy of Oral Trihexyphenidyl Plus Clonazepam Versus Trihexyphenidyl for the Treatment of Dystonia in Children With Dystonic Cerebral Palsy: An Open-Label Randomized Controlled Trial.
Kumar Panda P, Moirangthem V, Tomar A, Neyaz O, Sharawat IK. Kumar Panda P, et al. Pediatr Neurol. 2024 Sep;158:35-40. doi: 10.1016/j.pediatrneurol.2024.06.004. Epub 2024 Jun 14. Pediatr Neurol. 2024. PMID: 38945037 Clinical Trial.
BACKGROUND: Trihexyphenidyl and clonazepam are commonly used to treat dystonia in children with cerebral palsy (CP). ...METHODS: This open-label, randomized controlled trial aimed to compare the efficacy of adding oral clonazepam to trihexyphenidyl (THP + CLZ) versu …
BACKGROUND: Trihexyphenidyl and clonazepam are commonly used to treat dystonia in children with cerebral palsy (CP). ...METHODS: This …
Adjuvant therapy of parkinsonian tremor.
Koller WC, Herbster G. Koller WC, et al. Arch Neurol. 1987 Sep;44(9):921-3. doi: 10.1001/archneur.1987.00520210023013. Arch Neurol. 1987. PMID: 3619710 Clinical Trial.
Comparison of central and peripheral pharmacologic effects of biperiden and trihexyphenidyl in human volunteers.
Guthrie SK, Manzey L, Scott D, Giordani B, Tandon R. Guthrie SK, et al. J Clin Psychopharmacol. 2000 Feb;20(1):77-83. doi: 10.1097/00004714-200002000-00013. J Clin Psychopharmacol. 2000. PMID: 10653212 Clinical Trial.
On the VAS, subjects rated biperiden as significantly more sedating than either trihexyphenidyl or placebo, and both biperiden and trihexyphenidyl were associated with more dizziness than was placebo. ...With the exception of the VAS measurement of sedation, the eff …
On the VAS, subjects rated biperiden as significantly more sedating than either trihexyphenidyl or placebo, and both biperiden and …
A placebo-controlled trial of trihexyphenidyl in unmedicated patients with schizophrenia.
Goff DC, Amico E, Dreyfuss D, Ciraulo D. Goff DC, et al. Am J Psychiatry. 1994 Mar;151(3):429-31. doi: 10.1176/ajp.151.3.429. Am J Psychiatry. 1994. PMID: 8109654 Clinical Trial.
Seventeen patients with schizophrenia who had been free of medication for at least 2 months entered a placebo-controlled, random-order crossover trial of 5 mg of trihexyphenidyl twice daily for 4 weeks. Ten patients completed trials of both drug and placebo. Ratings of ant …
Seventeen patients with schizophrenia who had been free of medication for at least 2 months entered a placebo-controlled, random-order cross …
Elantrine in the treatment of parkinsonism.
Blonsky ER. Blonsky ER. Neurol Neurocir Psiquiatr. 1976;17(4):231-8. Neurol Neurocir Psiquiatr. 1976. PMID: 798127 Clinical Trial.
A double blind study compared elantrine with trinhexyphenidyl and against a baseline placebo period, in a group of Parkinson patients. Both, elantrine and trihexyphenidyl treatment, reduced tremor scores at the conclusion of the respective treatment periods, but closer ana …
A double blind study compared elantrine with trinhexyphenidyl and against a baseline placebo period, in a group of Parkinson patients. Both, …
99 results