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Year Number of Results
1994 1
1996 1
1998 1
2000 2
2003 1
2005 1
2006 3
2007 2
2008 3
2009 6
2010 21
2011 21
2012 31
2013 30
2014 33
2015 29
2016 53
2017 53
2018 56
2019 43
2020 30
2021 5
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358 results
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Page 1
Ulipristal acetate versus leuprolide acetate for uterine fibroids.
Donnez J, Tomaszewski J, Vázquez F, Bouchard P, Lemieszczuk B, Baró F, Nouri K, Selvaggi L, Sodowski K, Bestel E, Terrill P, Osterloh I, Loumaye E; PEARL II Study Group. Donnez J, et al. N Engl J Med. 2012 Feb 2;366(5):421-32. doi: 10.1056/NEJMoa1103180. N Engl J Med. 2012. PMID: 22296076 Free article. Clinical Trial.
Median times to amenorrhea were 7 days for patients receiving 5 mg of ulipristal acetate, 5 days for those receiving 10 mg of ulipristal acetate, and 21 days for those receiving leuprolide acetate. Moderate-to-severe hot flashes were reported for 11% of patients rec …
Median times to amenorrhea were 7 days for patients receiving 5 mg of ulipristal acetate, 5 days for those receiving 10 mg of ulip
Ulipristal acetate versus placebo for fibroid treatment before surgery.
Donnez J, Tatarchuk TF, Bouchard P, Puscasiu L, Zakharenko NF, Ivanova T, Ugocsai G, Mara M, Jilla MP, Bestel E, Terrill P, Osterloh I, Loumaye E; PEARL I Study Group. Donnez J, et al. N Engl J Med. 2012 Feb 2;366(5):409-20. doi: 10.1056/NEJMoa1103182. N Engl J Med. 2012. PMID: 22296075 Free article. Clinical Trial.
RESULTS: At 13 weeks, uterine bleeding was controlled in 91% of the women receiving 5 mg of ulipristal acetate, 92% of those receiving 10 mg of ulipristal acetate, and 19% of those receiving placebo (P<0.001 for the comparison of each dose of ulipristal ac …
RESULTS: At 13 weeks, uterine bleeding was controlled in 91% of the women receiving 5 mg of ulipristal acetate, 92% of those receivin …
Ulipristal acetate versus levonorgestrel for emergency contraception: a randomised non-inferiority trial and meta-analysis.
Glasier AF, Cameron ST, Fine PM, Logan SJ, Casale W, Van Horn J, Sogor L, Blithe DL, Scherrer B, Mathe H, Jaspart A, Ulmann A, Gainer E. Glasier AF, et al. Lancet. 2010 Feb 13;375(9714):555-62. doi: 10.1016/S0140-6736(10)60101-8. Epub 2010 Jan 29. Lancet. 2010. PMID: 20116841 Clinical Trial.
FINDINGS: In the efficacy-evaluable population, 1696 women received emergency contraception within 72 h of sexual intercourse (ulipristal acetate, n=844; levonorgestrel, n=852). There were 15 pregnancies in the ulipristal acetate group (1.8%, 95% CI 1.0-3.0) and 22 …
FINDINGS: In the efficacy-evaluable population, 1696 women received emergency contraception within 72 h of sexual intercourse (ulipristal
Uterine fibroid management: from the present to the future.
Donnez J, Dolmans MM. Donnez J, et al. Hum Reprod Update. 2016 Nov;22(6):665-686. doi: 10.1093/humupd/dmw023. Epub 2016 Jul 27. Hum Reprod Update. 2016. PMID: 27466209 Free PMC article. Review.
The economic impact of uterine fibroid management is significant and it is imperative that new treatments be developed to provide alternatives to surgical intervention.There is growing evidence of the crucial role of progesterone pathways in the pathophysiology of uterine fibroid …
The economic impact of uterine fibroid management is significant and it is imperative that new treatments be developed to provide alternativ …
Long-term medical management of uterine fibroids with ulipristal acetate.
Donnez J, Donnez O, Matule D, Ahrendt HJ, Hudecek R, Zatik J, Kasilovskiene Z, Dumitrascu MC, Fernandez H, Barlow DH, Bouchard P, Fauser BC, Bestel E, Loumaye E. Donnez J, et al. Fertil Steril. 2016 Jan;105(1):165-173.e4. doi: 10.1016/j.fertnstert.2015.09.032. Epub 2015 Oct 23. Fertil Steril. 2016. PMID: 26477496 Free article. Clinical Trial.
OBJECTIVE: To investigate the efficacy and safety of repeated 12-week courses of 5 or 10 mg daily ulipristal acetate for intermittent treatment of symptomatic uterine fibroids. DESIGN: Double-blind, randomized administration of four 12-week courses of ulipristal ace …
OBJECTIVE: To investigate the efficacy and safety of repeated 12-week courses of 5 or 10 mg daily ulipristal acetate for intermittent …
Emergency Contraception.
Batur P, Kransdorf LN, Casey PM. Batur P, et al. Mayo Clin Proc. 2016 Jun;91(6):802-7. doi: 10.1016/j.mayocp.2016.02.018. Mayo Clin Proc. 2016. PMID: 27261868 Free article. Review.
There are 4 approved EC options in the United States. Although ulipristal acetate requires a provider's prescription, oral levonorgestrel (LNG) is available over the counter for women of all ages. ...Women who weigh more than 75 kg or have a body mass index greater than 25 …
There are 4 approved EC options in the United States. Although ulipristal acetate requires a provider's prescription, oral levonorges …
Choice of contraceptives.
[No authors listed] [No authors listed] Med Lett Drugs Ther. 2018 Oct 8;60(1557):161-168. Med Lett Drugs Ther. 2018. PMID: 30335731 No abstract available.
Emergency Contraception.
Upadhya KK; COMMITTEE ON ADOLESCENCE. Upadhya KK, et al. Pediatrics. 2019 Dec;144(6):e20193149. doi: 10.1542/peds.2019-3149. Epub 2019 Nov 18. Pediatrics. 2019. PMID: 31740497 Free article. Review.
Emergency contraceptive methods include oral medications labeled and dedicated for use as EC by the US Food and Drug Administration (ulipristal and levonorgestrel), the "off-label" use of combined oral contraceptives, and insertion of a copper intrauterine de …
Emergency contraceptive methods include oral medications labeled and dedicated for use as EC by the US Food and Drug Administration ( …
Emerging treatment options for uterine fibroids.
Donnez J, Arriagada P, Donnez O, Dolmans MM. Donnez J, et al. Expert Opin Emerg Drugs. 2018 Mar;23(1):17-23. doi: 10.1080/14728214.2018.1446943. Epub 2018 Mar 12. Expert Opin Emerg Drugs. 2018. PMID: 29486606 Review.
Areas covered: There is growing evidence of the crucial role of progesterone pathways in the pathophysiology of uterine fibroids, leading to increasing use of selective progesterone receptor modulators (SPRMs) such as ulipristal acetate. ...
Areas covered: There is growing evidence of the crucial role of progesterone pathways in the pathophysiology of uterine fibroids, leading to …
Emergency contraception and impact on abortion rates.
Michie L, Cameron ST. Michie L, et al. Best Pract Res Clin Obstet Gynaecol. 2020 Feb;63:111-119. doi: 10.1016/j.bpobgyn.2019.06.008. Epub 2019 Jul 3. Best Pract Res Clin Obstet Gynaecol. 2020. PMID: 31362908 Review.
The most effective EC is the copper-bearing intrauterine device (Cu-IUD), but oral EC methods are more commonly used and include a single dose of either levonorgestrel (1.5 mg) or ulipristal acetate (30 mg). Although all EC methods are extremely safe, access to EC is often …
The most effective EC is the copper-bearing intrauterine device (Cu-IUD), but oral EC methods are more commonly used and include a single do …
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