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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 2
1972 1
1973 3
1974 2
1975 5
1976 6
1977 3
1978 1
1979 1
1981 1
1982 1
1984 3
1985 5
1986 2
1987 2
1988 2
1989 3
1990 4
1991 6
1992 8
1993 5
1994 6
1995 13
1996 6
1997 8
1998 10
1999 5
2000 8
2001 9
2002 11
2003 5
2004 7
2005 5
2006 13
2007 12
2008 5
2009 13
2010 11
2011 13
2012 16
2013 11
2014 17
2015 7
2016 6
2017 10
2018 9
2019 11
2020 11
2021 8
2022 11
2023 7
2024 4
2025 10
2026 8

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347 results

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Page 1
Antimicrobial efficacy of Xylitol, Probiotic and Chlorhexidine mouth rinses among children and elderly population at high risk for dental caries - A Randomized Controlled Trial.
Krupa NC, Thippeswamy HM, Chandrashekar BR. Krupa NC, et al. J Prev Med Hyg. 2022 Jul 31;63(2):E282-E287. doi: 10.15167/2421-4248/jpmh2022.63.2.1772. eCollection 2022 Jun. J Prev Med Hyg. 2022. PMID: 35968060 Free PMC article. Clinical Trial.
CONCLUSIONS: Antimicrobial efficacy of xylitol and probiotic mouth rinses were comparable to that of chlorhexidine in both children and elderly. Probiotics could potentially be more efficacious than xylitol among children....
CONCLUSIONS: Antimicrobial efficacy of xylitol and probiotic mouth rinses were comparable to that of chlorhexidine in both children a …
Effects of Gum Chewing on Recovery From Postoperative Ileus: A Randomized Clinical Trail.
Hsu YC, Szu SY. Hsu YC, et al. J Nurs Res. 2022 Oct 1;30(5):e233. doi: 10.1097/jnr.0000000000000510. J Nurs Res. 2022. PMID: 35951432 Clinical Trial.
The intervention group ( n = 30) received xylitol chewing gum on the first day after colon resection, one piece of gum for 15 minutes, 3 times daily, until the time to first flatus and defecation. ...
The intervention group ( n = 30) received xylitol chewing gum on the first day after colon resection, one piece of gum for 15 minutes …
Effectiveness of fluoride and xylitol varnishes in treating post-orthodontic white spot lesions: a randomized clinical trial.
Zarif Najafi H, Shavakhi M. Zarif Najafi H, et al. Eur J Orthod. 2025 Jun 12;47(4):cjaf047. doi: 10.1093/ejo/cjaf047. Eur J Orthod. 2025. PMID: 40501274 Free article. Clinical Trial.
OBJECTIVES: This study evaluated the remineralizing effects of 10% xylitol varnish, 5% fluoride varnish, and placebo on WSLs after orthodontic treatment. ...No significant difference in WSL reduction was noted between the xylitol and placebo groups. CONCLUSIONS: Bot …
OBJECTIVES: This study evaluated the remineralizing effects of 10% xylitol varnish, 5% fluoride varnish, and placebo on WSLs after or …
Randomized clinical trial on the clinical effects of a toothpaste containing extra virgin olive oil, xylitol, and betaine in gingivitis.
Rodríguez-Agurto A, Bravo M, Magán-Fernandez A, López-Toruño A, Muñoz R, Ferrer J, Mesa F. Rodríguez-Agurto A, et al. Sci Rep. 2023 Apr 18;13(1):6294. doi: 10.1038/s41598-023-33521-4. Sci Rep. 2023. PMID: 37072503 Free PMC article. Clinical Trial.
To determine the effects on gingival bleeding, dental biofilm, and salivary flow and pH in patients with gingivitis of using toothpaste with extra-virgin olive oil (EVOO), xylitol, and betaine in comparison to a placebo or commercial toothpaste. This controlled, double bli …
To determine the effects on gingival bleeding, dental biofilm, and salivary flow and pH in patients with gingivitis of using toothpaste with …
Metabolic response to lactitol and xylitol in healthy men.
Natah SS, Hussien KR, Tuominen JA, Koivisto VA. Natah SS, et al. Am J Clin Nutr. 1997 Apr;65(4):947-50. doi: 10.1093/ajcn/65.4.947. Am J Clin Nutr. 1997. PMID: 9094877 Clinical Trial.

After the ingestion of lactitol or xylitol, the rise in plasma glucose, insulin, and C-peptide concentrations was less than after the ingestion of glucose (P < 0.02), with no difference between the two polyols. ...The small glucose and insulin responses also suggest tha

…
After the ingestion of lactitol or xylitol, the rise in plasma glucose, insulin, and C-peptide concentrations was less than after the …
Xylitol and dental caries.
Mäkinen KK, Scheinin A. Mäkinen KK, et al. Annu Rev Nutr. 1982;2:133-50. doi: 10.1146/annurev.nu.02.070182.001025. Annu Rev Nutr. 1982. PMID: 6764729 Review. No abstract available.
Effectiveness of chlorhexidine and xylitol varnish versus silver diamine fluoride in the control of initial dental caries lesions: a randomised clinical trial.
Magalhães Cairo G, Cardoso Oliveira M, Meira Maia V, Neves Oliveira IF, Neves Souza Gomes MJ, Augusto Casotti C. Magalhães Cairo G, et al. Eur J Paediatr Dent. 2026 Mar 1;27:1. doi: 10.23804/ejpd.2026.2361. Eur J Paediatr Dent. 2026. PMID: 41874201 Free article. Clinical Trial.
AIM: This study aims to compare the effectiveness of a chlorhexidine (2%) and xylitol (5%) varnish (VCX) versus a silver diamine fluoride (SDF) solution (30%) in controlling initial dental caries lesions in young children. ...
AIM: This study aims to compare the effectiveness of a chlorhexidine (2%) and xylitol (5%) varnish (VCX) versus a silver diamine fluo …
A cluster randomized trial of xylitol chewing gum for prevention of preterm birth: The PPaX trial.
Valentine GC, Antony KM, Sangi-Haghpeykar H, Wood AC, Chirwa R, Petro S, Dumba M, Nanthuru D, Shope C, Mlotha-Namarika J, Wilkinson J, Aagaard J, Aagaard EJ, Seferovic MD, Levison J, Kazembe P, Aagaard KM. Valentine GC, et al. Med. 2025 Apr 11;6(4):100539. doi: 10.1016/j.medj.2024.10.016. Epub 2024 Nov 13. Med. 2025. PMID: 39541971 Free article. Clinical Trial.
Xylitol chewing gum use also led to fewer neonatal demises (0.2% [8/4,305] vs. 0.4% [22/5,260]; RR 0.41, 95% CI 0.19-0.89). CONCLUSIONS: Periconception initiation and ongoing use of xylitol chewing gum significantly reduced the occurrence of preterm and low-birthwei …
Xylitol chewing gum use also led to fewer neonatal demises (0.2% [8/4,305] vs. 0.4% [22/5,260]; RR 0.41, 95% CI 0.19-0.89). CONCLUSIO …
Prevention of non-cavitated lesions with fluoride and xylitol varnishes during orthodontic treatment: a randomized clinical trial.
Silva VM, Massaro C, Buzalaf MAR, Janson G, Garib D. Silva VM, et al. Clin Oral Investig. 2021 Jun;25(6):3421-3430. doi: 10.1007/s00784-021-03930-8. Epub 2021 Apr 9. Clin Oral Investig. 2021. PMID: 33835256 Clinical Trial.
The patients in each group received two applications of the following varnishes: Duraphat(TM) (5% NaF), 20% xylitol, and placebo (no F/Xylitol) in the three groups, respectively. The varnishes were applied in the first appointment (T0) and 3 months later (T1). ...Th …
The patients in each group received two applications of the following varnishes: Duraphat(TM) (5% NaF), 20% xylitol, and placebo (no …
347 results