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26 results

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Page 1
Zinc in the physiology and pathology of the CNS.
Sensi SL, Paoletti P, Bush AI, Sekler I. Sensi SL, et al. Nat Rev Neurosci. 2009 Nov;10(11):780-91. doi: 10.1038/nrn2734. Epub 2009 Oct 14. Nat Rev Neurosci. 2009. PMID: 19826435 Review.
The past few years have witnessed dramatic progress on all frontiers of zinc neurobiology. The recent development of powerful tools, including zinc-sensitive fluorescent probes, selective chelators and genetically modified animal models, has brought a deeper underst …
The past few years have witnessed dramatic progress on all frontiers of zinc neurobiology. The recent development of powerful tools, …
Application of Polymeric Nanoparticles for CNS Targeted Zinc Delivery In Vivo.
Chhabra R, Ruozi B, Vilella A, Belletti D, Mangus K, Pfaender S, Sarowar T, Boeckers TM, Zoli M, Forni F, Vandelli MA, Tosi G, Grabrucker AM. Chhabra R, et al. CNS Neurol Disord Drug Targets. 2015;14(8):1041-53. doi: 10.2174/1871527314666150821111455. CNS Neurol Disord Drug Targets. 2015. PMID: 26295815
Here, we performed in vivo studies investigating the possibility of brain targeted zinc delivery using zinc-loaded nanoparticles which are able to cross the blood-brain barrier. After injecting these nanoparticles, we analyzed the regional and time-dependent distrib …
Here, we performed in vivo studies investigating the possibility of brain targeted zinc delivery using zinc-loaded nanoparticl …
Cation-Stress-Responsive Transcription Factors SltA and CrzA Regulate Morphogenetic Processes and Pathogenicity of Colletotrichum gloeosporioides.
Dubey AK, Barad S, Luria N, Kumar D, Espeso EA, Prusky DB. Dubey AK, et al. PLoS One. 2016 Dec 28;11(12):e0168561. doi: 10.1371/journal.pone.0168561. eCollection 2016. PLoS One. 2016. PMID: 28030573 Free PMC article.
Previous reports indicate that adaptation of Aspergillus nidulans to salt- and osmotic-stress conditions revealed the role of zinc-finger transcription factors SltA and CrzA in cation homeostasis. Homologs of A. nidulans SltA and CrzA were identified in C. gloeosporioides. …
Previous reports indicate that adaptation of Aspergillus nidulans to salt- and osmotic-stress conditions revealed the role of zinc-fi …
Meeting a threat of the Anthropocene: Taste avoidance of metal ions by Drosophila.
Xiao S, Baik LS, Shang X, Carlson JR. Xiao S, et al. Proc Natl Acad Sci U S A. 2022 Jun 21;119(25):e2204238119. doi: 10.1073/pnas.2204238119. Epub 2022 Jun 14. Proc Natl Acad Sci U S A. 2022. PMID: 35700364 Free PMC article.
Feeding avoidance remains stable over 10 generations of exposure to copper and zinc ions. Some responses to metal ions are conserved across diverse dipteran species, including the mosquito Aedes albopictus. ...
Feeding avoidance remains stable over 10 generations of exposure to copper and zinc ions. Some responses to metal ions are conserved …
Zinc oxide-engineered nanoparticles: dissolution and toxicity to marine phytoplankton.
Miao AJ, Zhang XY, Luo Z, Chen CS, Chin WC, Santschi PH, Quigg A. Miao AJ, et al. Environ Toxicol Chem. 2010 Dec;29(12):2814-22. doi: 10.1002/etc.340. Epub 2010 Oct 7. Environ Toxicol Chem. 2010. PMID: 20931607
In the present study, it was found that ZnO-engineered nanoparticle (ZnO-EN) toxicity to the marine diatom Thalassiosira pseudonana could be solely explained by zinc ion (Zn(2+) ) release. This is based on comparable inhibitive effects from ZnO-EN addition media, with or w …
In the present study, it was found that ZnO-engineered nanoparticle (ZnO-EN) toxicity to the marine diatom Thalassiosira pseudonana could be …
Differential gene expression in Daphnia magna suggests distinct modes of action and bioavailability for ZnO nanoparticles and Zn ions.
Poynton HC, Lazorchak JM, Impellitteri CA, Smith ME, Rogers K, Patra M, Hammer KA, Allen HJ, Vulpe CD. Poynton HC, et al. Environ Sci Technol. 2011 Jan 15;45(2):762-8. doi: 10.1021/es102501z. Epub 2010 Dec 13. Environ Sci Technol. 2011. PMID: 21142172
Zinc oxide nanoparticles (ZnO NPs) are being rapidly developed for use in consumer products, wastewater treatment, and chemotherapy providing several possible routes for ZnO NP exposure to humans and aquatic organisms. ...
Zinc oxide nanoparticles (ZnO NPs) are being rapidly developed for use in consumer products, wastewater treatment, and chemotherapy p …
Mercuric ions inhibit mitogen-activated protein kinase dephosphorylation by inducing reactive oxygen species.
Haase H, Engelhardt G, Hebel S, Rink L. Haase H, et al. Toxicol Appl Pharmacol. 2011 Jan 1;250(1):78-86. doi: 10.1016/j.taap.2010.10.007. Epub 2010 Oct 14. Toxicol Appl Pharmacol. 2011. PMID: 20951154
Therefore, the objective of this study is to investigate three potential ways in which Hg(2+) ions could inhibit MAPK dephosphorylation in the human T-cell line Jurkat: (1) by direct binding to phosphatases; (2) by releasing cellular zinc (Zn(2+)); and (3) by inducing reac …
Therefore, the objective of this study is to investigate three potential ways in which Hg(2+) ions could inhibit MAPK dephosphorylation in t …
26 results