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A randomised, single-blind, single-centre clinical trial to evaluate comparative clinical efficacy of shampoos containing ciclopirox olamine (1.5%) and salicylic acid (3%), or ketoconazole (2%, Nizoral) for the treatment of dandruff/seborrhoeic dermatitis.
Squire RA, Goode K. Squire RA, et al. J Dermatolog Treat. 2002 Jun;13(2):51-60. doi: 10.1080/095466302317584395. J Dermatolog Treat. 2002. PMID: 12060502 Clinical Trial.
Symptoms include scalp itchiness and scaling. Due to its antimycotic activity, ciclopirox olamine is established as an effective treatment for these scalp conditions. ...OBJECTIVE: To compare the therapeutic efficacy of a shampoo containing 1.5% ciclopirox olamine a …
Symptoms include scalp itchiness and scaling. Due to its antimycotic activity, ciclopirox olamine is established as an effective trea …
Double-blind clinical trial for evaluating the effectiveness and tolerability of Ageratina pichinchensis extract on patients with mild to moderate onychomycosis. A comparative study with ciclopirox.
Romero-Cerecero O, Zamilpa A, Jiménez-Ferrer JE, Rojas-Bribiesca G, Román-Ramos R, Tortoriello J. Romero-Cerecero O, et al. Planta Med. 2008 Oct;74(12):1430-5. doi: 10.1055/s-2008-1081338. Epub 2008 Jul 31. Planta Med. 2008. PMID: 18671197 Clinical Trial.
A phytopharmaceutical formulation was developed in a lacquer solution containing the standardized (encecalin) extract of A. PICHINCHENSIS. A similar lacquer solution containing 8 % ciclopirox was used as control. Treatments were assigned randomly and administered topically …
A phytopharmaceutical formulation was developed in a lacquer solution containing the standardized (encecalin) extract of A. PICHINCHENSIS. A …
Ciclopirox olamine lotion 1%: bioequivalence to ciclopirox olamine cream 1% and clinical efficacy in tinea pedis.
Aly R, Maibach HI, Bagatell FK, Dittmar W, Hänel H, Falanga V, Leyden JJ, Roth HL, Stoughton RB, Willis I, et al. Aly R, et al. Clin Ther. 1989 May-Jun;11(3):290-303. Clin Ther. 1989. PMID: 2663159 Clinical Trial.
Studies were conducted to assess the bioequivalence of a new antimycotic formulation, ciclopirox olamine lotion 1%, to an established compound, ciclopirox olamine cream 1%. ...Minor localized side effects (pruritus, burning sensation) were reported in 2% of 89 patie …
Studies were conducted to assess the bioequivalence of a new antimycotic formulation, ciclopirox olamine lotion 1%, to an established …
Comparative clinical evaluation of efficacy and safety of a formulation containing ciclopirox 8% in the form of a therapeutic nail lacquer in two different posologies for the treatment of onychomycosis of the toes.
Schalka S, Nunes S, Gomes Neto A. Schalka S, et al. An Bras Dermatol. 2012 Jan-Feb;87(1):19-25. doi: 10.1590/s0365-05962012000100002. An Bras Dermatol. 2012. PMID: 22481647 Clinical Trial.
OBJECTIVE: To evaluate the efficacy and safety of a nail lacquer formulation containing ciclopirox 8% in two different posologies: the traditional regimen (3/2/1) and a regimen of weekly use. ...Both groups had significant levels of mycological cure, clinical response and …
OBJECTIVE: To evaluate the efficacy and safety of a nail lacquer formulation containing ciclopirox 8% in two different posologies: th …
Multicentre double-blind clinical trials of ciclopirox olamine cream 1% in the treatment of tinea corporis and tinea cruris.
Bogaert H, Cordero C, Ollague W, Savin RC, Shalita AR, Zaias N. Bogaert H, et al. J Int Med Res. 1986;14(4):210-6. doi: 10.1177/030006058601400408. J Int Med Res. 1986. PMID: 3530834 Clinical Trial.
In separate multicentre, randomized, double-blind clinical trials, 1% ciclopirox olamine cream was compared with its cream vehicle and with 1% clotrimazole cream as treatment for tinea corporis and tinea cruris. ...These results were maintained through the two-week drug-fr …
In separate multicentre, randomized, double-blind clinical trials, 1% ciclopirox olamine cream was compared with its cream vehicle an …
Ciclopirox gel in the treatment of patients with interdigital tinea pedis.
Aly R, Fisher G, Katz I, Levine N, Lookingbill DP, Lowe N, Menter A, Morman M, Pariser DM, Roth HL, Savin RC, Shavin JS, Stewart D, Taylor JR, Tucker S, Wortzman M. Aly R, et al. Int J Dermatol. 2003 Sep;42 Suppl 1:29-35. doi: 10.1046/j.1365-4362.42.s1.6.x. Int J Dermatol. 2003. PMID: 14567368 Clinical Trial.
METHODS: Three hundred and seventy-four subjects were enrolled and randomized to one of two treatment groups: ciclopirox gel 0.77%, or ciclopirox gel vehicle, applied twice daily for 28 days, with a final visit up to day 50. ...At the same time point, 66% of cicl
METHODS: Three hundred and seventy-four subjects were enrolled and randomized to one of two treatment groups: ciclopirox gel 0.77%, o …
An open randomized comparative study to test the efficacy and safety of oral terbinafine pulse as a monotherapy and in combination with topical ciclopirox olamine 8% or topical amorolfine hydrochloride 5% in the treatment of onychomycosis.
Jaiswal A, Sharma RP, Garg AP. Jaiswal A, et al. Indian J Dermatol Venereol Leprol. 2007 Nov-Dec;73(6):393-6. doi: 10.4103/0378-6323.37056. Indian J Dermatol Venereol Leprol. 2007. PMID: 18032857 Clinical Trial.
AIMS: To study the efficacy and safety of oral terbinafine pulse as a monotherapy and in combination with topical ciclopirox olamine 8% or topical amorolfine hydrochloride 5% in onychomycosis. ...CONCLUSION: Terbinafine pulse therapy is effective and safe alternative in tr …
AIMS: To study the efficacy and safety of oral terbinafine pulse as a monotherapy and in combination with topical ciclopirox olamine …
Oral ciclopirox olamine displays biological activity in a phase I study in patients with advanced hematologic malignancies.
Minden MD, Hogge DE, Weir SJ, Kasper J, Webster DA, Patton L, Jitkova Y, Hurren R, Gronda M, Goard CA, Rajewski LG, Haslam JL, Heppert KE, Schorno K, Chang H, Brandwein JM, Gupta V, Schuh AC, Trudel S, Yee KW, Reed GA, Schimmer AD. Minden MD, et al. Am J Hematol. 2014 Apr;89(4):363-8. doi: 10.1002/ajh.23640. Epub 2014 Mar 3. Am J Hematol. 2014. PMID: 24273151 Free article. Clinical Trial.
The antimycotic ciclopirox olamine is an intracellular iron chelator that has anticancer activity in vitro and in vivo. ...Plasma concentrations of an inactive ciclopirox glucuronide metabolite were greater than those of ciclopirox. ...
The antimycotic ciclopirox olamine is an intracellular iron chelator that has anticancer activity in vitro and in vivo. ...Plasma con …
Clinical efficacies of shampoos containing ciclopirox olamine (1.5%) and ketoconazole (2.0%) in the treatment of seborrhoeic dermatitis.
Ratnavel RC, Squire RA, Boorman GC. Ratnavel RC, et al. J Dermatolog Treat. 2007;18(2):88-96. doi: 10.1080/16537150601092944. J Dermatolog Treat. 2007. PMID: 17520465 Clinical Trial.
BACKGROUND: Ciclopirox olamine (CPO) is a broad-spectrum antifungal with anti-inflammatory properties effective against the yeast implicated in seborrhoeic dermatitis, Malassezia spp. ...
BACKGROUND: Ciclopirox olamine (CPO) is a broad-spectrum antifungal with anti-inflammatory properties effective against the yeast imp …
Treatment of Onychomycosis - a Clinical Study.
Pajaziti L, Vasili E. Pajaziti L, et al. Med Arch. 2015 Jun;69(3):173-6. doi: 10.5455/medarh.2015.69.173-176. Epub 2015 Jun 10. Med Arch. 2015. PMID: 26261386 Free PMC article. Clinical Trial.
These groups were randomly subdivided to 5 subgroups according to the given treatment protocols: fluconazole 150 mg 1x weekly, itraconazole continual therapy, itraconazole pulse therapy, terbinafine 250 mg/d, and terbinafine + ciclopirox 8% lacquer, respectively. The cure …
These groups were randomly subdivided to 5 subgroups according to the given treatment protocols: fluconazole 150 mg 1x weekly, itraconazole …
79 results