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Year Number of Results
1970 3
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1972 10
1973 10
1974 13
1975 18
1976 14
1977 19
1978 18
1979 15
1980 34
1981 30
1982 32
1983 42
1984 30
1985 36
1986 37
1987 48
1988 62
1989 71
1990 51
1991 78
1992 68
1993 66
1994 76
1995 88
1996 70
1997 93
1998 86
1999 76
2000 83
2001 72
2002 65
2003 65
2004 68
2005 81
2006 53
2007 48
2008 46
2009 52
2010 32
2011 47
2012 40
2013 39
2014 53
2015 32
2016 39
2017 23
2018 23
2019 25
2020 22
2021 20
2022 15
2023 14
2024 14
2025 3

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2,289 results

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Page 1
Effect of propranolol and clonidine after severe traumatic brain injury: a pilot randomized clinical trial.
Nordness MF, Maiga AW, Wilson LD, Koyama T, Rivera EL, Rakhit S, de Riesthal M, Motuzas CL, Cook MR, Gupta DK, Jackson JC, Williams Roberson S, Meurer WJ, Lewis RJ, Manley GT, Pandharipande PP, Patel MB. Nordness MF, et al. Crit Care. 2023 Jun 9;27(1):228. doi: 10.1186/s13054-023-04479-6. Crit Care. 2023. PMID: 37296432 Free PMC article. Clinical Trial.
OBJECTIVE: To evaluate the safety, feasibility, and efficacy of combined adrenergic blockade with propranolol and clonidine in patients with severe traumatic brain injury (TBI). BACKGROUND: Administration of adrenergic blockade after severe TBI is common. ...CONCLUSION: De …
OBJECTIVE: To evaluate the safety, feasibility, and efficacy of combined adrenergic blockade with propranolol and clonidine in patien …
Comparing intravenous dexmedetomidine and clonidine in hemodynamic changes and block following spinal anesthesia with ropivacaine in lower limb orthopedic surgery: a randomized clinical trial.
Javahertalab M, Susanabadi A, Modir H, Kamali A, Amani A, Almasi-Hashiani A. Javahertalab M, et al. Med Gas Res. 2020 Jan-Mar;10(1):1-7. doi: 10.4103/2045-9912.279977. Med Gas Res. 2020. PMID: 32189663 Free PMC article. Clinical Trial.
Dexmedetomidine (DEX) can prolong duration of anesthesia and shorten onset of sensory and motor block relative to clonidine. This study attempted to compare the efficacy of intravenous DEX and clonidine for hemodynamic changes and block after spinal anesthesia with …
Dexmedetomidine (DEX) can prolong duration of anesthesia and shorten onset of sensory and motor block relative to clonidine. This stu …
Clonidine and migraine.
Wood J, Lance J. Wood J, et al. Med J Aust. 1984 Mar 17;140(6):384. doi: 10.5694/j.1326-5377.1984.tb104128.x. Med J Aust. 1984. PMID: 6366492 Clinical Trial. No abstract available.
The Effect of Clonidine Premedication on Hemodynamic Changes Following Tracheal Intubation and Co(2) Gas Insufflation and Postoperative Shivering In Patients Undergoing Laparoscopic Cholecystectomy; a Randomized Clinical Trial.
Entezariasl M, Isazadehfar K, Raesi M. Entezariasl M, et al. Int Tinnitus J. 2024 Mar 21;27(2):174-182. doi: 10.5935/0946-5448.20230027. Int Tinnitus J. 2024. PMID: 38507632 Clinical Trial.
This study was conducted to evaluate the effects of clonidine on reducing hemodynamic changes during tracheal intubation and Carbon dioxide gas insufflation and postoperative shivering in patients undergoing laparoscopic cholecystectomy. ...There was no significant statist …
This study was conducted to evaluate the effects of clonidine on reducing hemodynamic changes during tracheal intubation and Carbon d …
A phase II clinical trial to assess the safety of clonidine in acute organophosphorus pesticide poisoning.
Perera PM, Jayamanna SF, Hettiarachchi R, Abeysinghe C, Karunatilake H, Dawson AH, Buckley NA. Perera PM, et al. Trials. 2009 Aug 20;10:73. doi: 10.1186/1745-6215-10-73. Trials. 2009. PMID: 19691854 Free PMC article. Clinical Trial.
Forty eight patients with acute organophosphate poisoning were randomized to receive either clonidine or placebo: Four to receive placebo and twelve to receive clonidine at each dose level. ...Further studies are needed to study the efficacy of clonidine as a …
Forty eight patients with acute organophosphate poisoning were randomized to receive either clonidine or placebo: Four to receive pla …
Clonidine augmentation in patients with schizophrenia: A double-blind, randomized placebo-controlled trial.
Kruiper C, Sommer IEC, Koster M, Bakker PR, Durston S, Oranje B. Kruiper C, et al. Schizophr Res. 2023 May;255:148-154. doi: 10.1016/j.schres.2023.03.039. Epub 2023 Mar 28. Schizophr Res. 2023. PMID: 36989672 Free article. Clinical Trial.
It increased in patients treated with clonidine over the treatment period, whereas it decreased in both the HC and patients treated with placebo. However, neither treatment nor group effects were found in sensory gating. Clonidine treatment was very well tolerated. …
It increased in patients treated with clonidine over the treatment period, whereas it decreased in both the HC and patients treated w …
Clinical trial of clonidine hydrochloride as an antisecretory agent in cholera.
Rabbani GH, Butler T, Patte D, Abud RL. Rabbani GH, et al. Gastroenterology. 1989 Aug;97(2):321-5. doi: 10.1016/0016-5085(89)90067-x. Gastroenterology. 1989. PMID: 2663610 Clinical Trial.
Clonidine hydrochloride (an alpha 2-adrenoceptor agonist) was tested for antisecretory effects in patients with cholera in a randomized controlled trial. ...We conclude that clonidine causes modest reduction of stool electrolyte loss but does not significantly reduc
Clonidine hydrochloride (an alpha 2-adrenoceptor agonist) was tested for antisecretory effects in patients with cholera in a randomiz
Clonidine Maintenance Prolongs Opioid Abstinence and Decouples Stress From Craving in Daily Life: A Randomized Controlled Trial With Ecological Momentary Assessment.
Kowalczyk WJ, Phillips KA, Jobes ML, Kennedy AP, Ghitza UE, Agage DA, Schmittner JP, Epstein DH, Preston KL. Kowalczyk WJ, et al. Am J Psychiatry. 2015 Aug 1;172(8):760-7. doi: 10.1176/appi.ajp.2014.14081014. Epub 2015 Mar 17. Am J Psychiatry. 2015. PMID: 25783757 Free PMC article. Clinical Trial.
OBJECTIVE: The authors tested whether clonidine blocks stress-induced seeking of heroin and cocaine. The study was also intended to confirm translational findings from a rat model of drug relapse by using ecological momentary assessment of patients' stress to test hypothes …
OBJECTIVE: The authors tested whether clonidine blocks stress-induced seeking of heroin and cocaine. The study was also intended to c …
Comparison of the Systemic and Local Pharmacokinetics of Clonidine Mucoadhesive Buccal Tablets with Reference Clonidine Oral Tablets in Healthy Volunteers: An Open-Label Randomised Cross-Over Trial.
Vasseur B, Dufour A, Houdas L, Goodwin H, Harries K, Emul NY, Hutchings S. Vasseur B, et al. Adv Ther. 2017 Aug;34(8):2022-2032. doi: 10.1007/s12325-017-0585-9. Epub 2017 Jul 19. Adv Ther. 2017. PMID: 28726169 Clinical Trial.
Clonidine MBT was considered to mimic a continuous release of clonidine in plasma, significantly decreasing the C (max) and AUC and increasing the T (max) when compared with the reference clonidine HCl tablets. Clonidine MBT exhibited high and prolonge
Clonidine MBT was considered to mimic a continuous release of clonidine in plasma, significantly decreasing the C (max) and AU
Transdermal clonidine versus chlordiazepoxide in alcohol withdrawal: a randomized, controlled clinical trial.
Baumgartner GR, Rowen RC. Baumgartner GR, et al. South Med J. 1991 Mar;84(3):312-21. doi: 10.1097/00007611-199103000-00006. South Med J. 1991. PMID: 2000517 Clinical Trial.
Also, clonidine more effectively lowered elevated systolic and diastolic blood pressure and heart rate. ...We conclude that transdermal clonidine is effective treatment for the acute alcohol withdrawal syndrome....
Also, clonidine more effectively lowered elevated systolic and diastolic blood pressure and heart rate. ...We conclude that transderm …
2,289 results