Structural insights of the elongation factor EF-Tu complexes in protein translation of Mycobacterium tuberculosis.
Zhan B, Gao Y, Gao W, Li Y, Li Z, Qi Q, Lan X, Shen H, Gan J, Zhao G, Li J.
Zhan B, et al.
Commun Biol. 2022 Oct 3;5(1):1052. doi: 10.1038/s42003-022-04019-y.
Commun Biol. 2022.
PMID: 36192483
Free PMC article.
Here, we report the crystal structures of Mtb EF-Tu EF-Ts and EF-Tu GDP complexes, showing the molecular basis of EF-Tu's representative recycling and inactive forms in protein translation. ...Also, the FDA-approved drug Osimertinib inhibits the growth of M. …
Here, we report the crystal structures of Mtb EF-Tu EF-Ts and EF-Tu GDP complexes, showing the molecular basis of EF-Tu …