Isolation of flavins from the Amazonian shrub Faramea guianesis

J Nat Prod. 1994 Mar;57(3):403-6. doi: 10.1021/np50105a014.

Abstract

In the pursuit of new leishmanicidal natural products, 5,7,4'-trihydroxyflavan [1] and the new product, 5,7-dihydroxy-4'-methoxyflavan [2], were isolated from the Guianian medicinal plant Faramea guianensis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antiprotozoal Agents / pharmacology
  • Flavins / isolation & purification*
  • Flavins / pharmacology
  • Guyana
  • Leishmania / drug effects
  • Leishmaniasis / drug therapy
  • Macrophages / drug effects
  • Macrophages / parasitology
  • Mice
  • Mice, Inbred BALB C
  • Plants, Medicinal / chemistry*

Substances

  • Antiprotozoal Agents
  • Flavins