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Page 1
[Maxacalcitol, a medicine for secondary hyperparathyroidism (2 degrees HPT)].
Imazeki I. Imazeki I. Nihon Yakurigaku Zasshi. 2003 Jan;121(1):65-72. doi: 10.1254/fpj.121.65. Nihon Yakurigaku Zasshi. 2003. PMID: 12617040 Review. Japanese.
It was reported that both serum PTH and PTH mRNA levels were suppressed by Maxacalcitol with less calcemic action and also Maxacalcitol could ameliorate high-turnover bone and marked osteitis fibrosa in uremic rats. Here I review many reports focused on the effects …
It was reported that both serum PTH and PTH mRNA levels were suppressed by Maxacalcitol with less calcemic action and also Maxacal …
Topical maxacalcitol for the treatment of psoriasis vulgaris: a placebo-controlled, double-blind, dose-finding study with active comparator.
Barker JN, Ashton RE, Marks R, Harris RI, Berth-Jones J. Barker JN, et al. Br J Dermatol. 1999 Aug;141(2):274-8. doi: 10.1046/j.1365-2133.1999.02975.x. Br J Dermatol. 1999. PMID: 10468799 Clinical Trial.
Calcipotriol ointment 50 microg/g once daily as active comparator had a similar effect. Marked improvement or clearance of psoriasis was greatest for maxacalcitol 25 microg/g (55% of subjects) which compared favourably with calcipotriol (46%). ...This study indicate …
Calcipotriol ointment 50 microg/g once daily as active comparator had a similar effect. Marked improvement or clearance of psoriasis …
Effects of maxacalcitol ointment on skin lesions in patients with psoriasis receiving treatment with adalimumab.
Karakawa M, Komine M, Kishimoto M, Maki N, Matsumoto A, Sugai J, Ohtsuki M. Karakawa M, et al. J Dermatol. 2016 Nov;43(11):1354-1357. doi: 10.1111/1346-8138.13515. Epub 2016 Jul 23. J Dermatol. 2016. PMID: 27450634 Clinical Trial.
Maxacalcitol is an active vitamin D3 ointment that is effective in treatment of psoriasis. ...The better control of skin lesions in patients who elongated the interval of adalimumab administration was achieved in the maxacalcitol combination group compared wi …
Maxacalcitol is an active vitamin D3 ointment that is effective in treatment of psoriasis. ...The better control of skin lesio …
The vitamin D(3) analog, maxacalcitol, reduces psoriasiform skin inflammation by inducing regulatory T cells and downregulating IL-23 and IL-17 production.
Hau CS, Shimizu T, Tada Y, Kamata M, Takeoka S, Shibata S, Mitsui A, Asano Y, Sugaya M, Kadono T, Sato S, Watanabe S. Hau CS, et al. J Dermatol Sci. 2018 Nov;92(2):117-126. doi: 10.1016/j.jdermsci.2018.08.007. Epub 2018 Aug 24. J Dermatol Sci. 2018. PMID: 30166055
OBJECTIVE: To compare the effects of a VD3 A maxacalcitol and betamethasone valerate (BV) steroid lotion on topical imiquimod (IMQ)-induced psoriasiform skin inflammation. ...CONCLUSION: These results indicate that maxacalcitol reduces psoriasiform ski …
OBJECTIVE: To compare the effects of a VD3 A maxacalcitol and betamethasone valerate (BV) steroid lotion on topical imiquimod (IMQ)-i …
Chronotherapy of maxacalcitol on skin inflammation induced by topical 12-O-tetradecanoylphorbol-13-acetate in mice.
Yoshioka D, Ando H, Ushijima K, Kumazaki M, Fujimura A. Yoshioka D, et al. Chronobiol Int. 2018 Sep;35(9):1269-1280. doi: 10.1080/07420528.2018.1474890. Epub 2018 May 18. Chronobiol Int. 2018. PMID: 29775091
In this study, a daily rhythm of skin vitamin D receptor (VDR) and chronotherapeutic profiles of maxacalcitol, a vitamin D analogue, were evaluated using mice with skin inflammation induced by topical 12-O-tetradecanoylphorbol-13-acetate (TPA). ...These data suggest that c …
In this study, a daily rhythm of skin vitamin D receptor (VDR) and chronotherapeutic profiles of maxacalcitol, a vitamin D analogue, …
In vivo assessment of the cutaneous bioavailability of topically applied maxacalcitol.
Ikeda Y, Hirata K, Kano S, Yanagihara H, Takahara J, Kondo K, Umemura K. Ikeda Y, et al. Methods Find Exp Clin Pharmacol. 2005 Jun;27(5):305-10. doi: 10.1358/mf.2005.27.5.908644. Methods Find Exp Clin Pharmacol. 2005. PMID: 16082417 Free article.
Maxacalcitol (22-oxacalcitriol), a vitamin D3 analogue, is widely used for the treatment of psoriasis. ...Maxacalcitol was extracted from the tape strips and quantified by liquid chromatographic tandem mass spectrometry. ...
Maxacalcitol (22-oxacalcitriol), a vitamin D3 analogue, is widely used for the treatment of psoriasis. ...Maxacalcitol …
Vitamine D analogue-based therapies for psoriasis.
O'Neill JL, Feldman SR. O'Neill JL, et al. Drugs Today (Barc). 2010 May;46(5):351-60. doi: 10.1358/dot.2010.46.5.1473264. Drugs Today (Barc). 2010. PMID: 20517536 Review.
Topical vitamin D3 analogues are a mainstay of treatment in mild to moderate plaque psoriasis. Vitamin D3 analogues exert their effect in psoriasis via binding nuclear vitamin D3 receptors on genes involved in cellular proliferation, differentiation and inflammation …
Topical vitamin D3 analogues are a mainstay of treatment in mild to moderate plaque psoriasis. Vitamin D3 analogues exert their effec …
Interventions for chronic palmoplantar pustulosis.
Obeid G, Do G, Kirby L, Hughes C, Sbidian E, Le Cleach L. Obeid G, et al. Cochrane Database Syst Rev. 2020 Jan 20;1(1):CD011628. doi: 10.1002/14651858.CD011628.pub2. Cochrane Database Syst Rev. 2020. PMID: 31958161 Free PMC article.
One trial (188 participants) assessed the topical vitamin D derivative maxacalcitol versus placebo and found that maxacalcitol may be more effective than placebo in achieving clearance (risk ratio (RR) 7.83, 95% confidence interval (CI) 1.85 to 33.12; low-quality ev …
One trial (188 participants) assessed the topical vitamin D derivative maxacalcitol versus placebo and found that maxacalcitol …
The Efficacy and Safety of Non-Biologic and Biologic Treatments in Palmoplantar Pustular Psoriasis and Palmoplantar Pustulosis: A Systematic Review and Network Meta-Analysis.
Alshareef KM, Abualola AH, Shaheen EA, Aljuaid AA, Alshibi F, Kalantan R, Bashrahil B, Alghowairi DH, Alamri AM. Alshareef KM, et al. Australas J Dermatol. 2025 Mar;66(2):53-60. doi: 10.1111/ajd.14410. Epub 2025 Jan 7. Australas J Dermatol. 2025. PMID: 39776413
Palmoplantar pustular psoriasis (PPPP), or palmoplantar pustulosis (PPP), is a type of psoriasis that affects the skin on the palms and soles. ...
Palmoplantar pustular psoriasis (PPPP), or palmoplantar pustulosis (PPP), is a type of psoriasis that affects the skin on the …
Combination therapy using maxacalcitol and corticosteroid lotions preliminary to monotherapy with maxacalcitol lotion for scalp psoriasis.
Okubo Y, Natsume S, Usui K, Muro M, Tsuboi R. Okubo Y, et al. J Dermatolog Treat. 2014 Feb;25(1):34-7. doi: 10.3109/09546634.2012.687087. Epub 2012 Jun 12. J Dermatolog Treat. 2014. PMID: 22515652 Free article. Clinical Trial.
Topical treatment with betamethasone butyrate propionate lotion on 37 patients with scalp psoriasis was replaced with a combination therapy using maxacalcitol lotion (on weekdays) and BBP (on the weekends). ...
Topical treatment with betamethasone butyrate propionate lotion on 37 patients with scalp psoriasis was replaced with a combination t …
57 results