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114 results

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Page 1
Tacalcitol.
Peters DC, Balfour JA. Peters DC, et al. Drugs. 1997 Aug;54(2):265-71; discussion 272. doi: 10.2165/00003495-199754020-00005. Drugs. 1997. PMID: 9257082 Review.
Tacalcitol inhibits proliferation, and induces the differentiation, of keratinocytes. In addition, it appears to modulate inflammatory and immunological mediators in the skin which may be involved in the aetiology of psoriasis. No significant systemic drug absorptio …
Tacalcitol inhibits proliferation, and induces the differentiation, of keratinocytes. In addition, it appears to modulate inflammator …
[Drug-induced hypercalcemia].
Sato K. Sato K. Clin Calcium. 2006 Jan;16(1):67-72. Clin Calcium. 2006. PMID: 16397353 Review. Japanese.
Recently, various analogs of 1,25- (OH) (2)D(3) with potent differentiation stimulating activity on keratinocytes but insufficient calcium-movilizing activity have been developed (tacalcitol, calcipotriol, 22-oxacalcitriol). However, severe hypercalcemia may develop when t …
Recently, various analogs of 1,25- (OH) (2)D(3) with potent differentiation stimulating activity on keratinocytes but insufficient calcium-m …
Topical tacalcitol treatment for psoriasis.
Harrison PV. Harrison PV. Hosp Med. 2000 Jun;61(6):402-5. doi: 10.12968/hosp.2000.61.6.1355. Hosp Med. 2000. PMID: 10962655 Review.
Multiple studies have shown the benefit of topical tacalcitol treatment for chronic plaque psoriasis. Tacalcitol ointment 4 micrograms/g is efficacious and well tolerated as both monotherapy and in combination with other treatments such as ultraviolet light t …
Multiple studies have shown the benefit of topical tacalcitol treatment for chronic plaque psoriasis. Tacalcitol ointme …
Tacalcitol: A useful adjunct to narrow band ultraviolet B phototherapy in psoriasis.
Aggarwal P, Aggarwal K, Jain VK. Aggarwal P, et al. J Dermatolog Treat. 2016 Nov;27(6):546-551. doi: 10.3109/09546634.2016.1163318. Epub 2016 Apr 7. J Dermatolog Treat. 2016. PMID: 27052200 Free article. Clinical Trial.
BACKGROUND: A combination of calcipotriol and narrow-band ultraviolet B (NBUVB) has been shown to have a superior efficacy as compared to NBUVB alone in psoriasis. Very few studies have been performed using the combination of NBUVB with tacalcitol, a comparatively n …
BACKGROUND: A combination of calcipotriol and narrow-band ultraviolet B (NBUVB) has been shown to have a superior efficacy as compared to NB …
Tacalcitol ointment in the treatment of psoriasis vulgaris: a multicentre, placebo-controlled, double-blind study on efficacy and safety.
Van de Kerkhof PC, Werfel T, Haustein UF, Luger T, Czarnetzki BM, Niemann R, Plänitz-Stenzel V. Van de Kerkhof PC, et al. Br J Dermatol. 1996 Nov;135(5):758-65. Br J Dermatol. 1996. PMID: 8977677 Clinical Trial.
Tacalcitol is a vitamin D analogue which ahs been developed for the therapy of psoriasis vulgaris. ...In only one patient, irritation required discontinuation of tacalcitol treatment. Laboratory criteria, including serum calcium, serum phosphate and serum lev …
Tacalcitol is a vitamin D analogue which ahs been developed for the therapy of psoriasis vulgaris. ...In only one patient, irr …
Newer agents for psoriasis in adults.
Jabbar-Lopez ZK, Wu KC, Reynolds NJ. Jabbar-Lopez ZK, et al. BMJ. 2014 Jul 9;349:g4026. doi: 10.1136/bmj.g4026. BMJ. 2014. PMID: 25008099 Review. No abstract available.
Profile of clinical efficacy and safety of topical tacalcitol.
Leone G, Pacifico A. Leone G, et al. Acta Biomed. 2005 Apr;76(1):13-9. Acta Biomed. 2005. PMID: 16116820 Review.
The purpose of this critical review of the literature is to evaluate the efficacy and tolerability of the synthesis of new analogues of the Vitamin D3 Tacalcitol, which is formulated in ointment form at a concentration of 4 microg/g, for the treatment of mild and/or modera …
The purpose of this critical review of the literature is to evaluate the efficacy and tolerability of the synthesis of new analogues of the …
Tacalcitol in the treatment of psoriasis vulgaris: the Spanish experience.
Lecha M, Mirada A, López S, Artés M; T.O.P. Research Group. Lecha M, et al. J Eur Acad Dermatol Venereol. 2005 Jul;19(4):414-7. doi: 10.1111/j.1468-3083.2005.01099.x. J Eur Acad Dermatol Venereol. 2005. PMID: 15987284 Clinical Trial.
OBJECTIVE: Evaluation of tolerability and efficacy of tacalcitol ointment in moderate psoriasis. DESIGN: A 2-month multicentre prospective open-label observational study in patients with psoriasis treated with tacalcitol ointment. ...Our results in an …
OBJECTIVE: Evaluation of tolerability and efficacy of tacalcitol ointment in moderate psoriasis. DESIGN: A 2-month multicentre …
1,24-Dihydroxyvitamin D3 (tacalcitol) prevents skin T-cell infiltration.
Yamanaka KI, Kakeda M, Kitagawa H, Tsuda K, Akeda T, Kurokawa I, Gabazza EC, Kupper TS, Mizutani H. Yamanaka KI, et al. Br J Dermatol. 2010 Jun;162(6):1206-15. doi: 10.1111/j.1365-2133.2010.09692.x. Epub 2010 Feb 15. Br J Dermatol. 2010. PMID: 20163421
BACKGROUND: 1,24-Dihydroxyvitamin D3 (tacalcitol), a vitamin D(3) compound, has been used to treat T cell-mediated inflammatory skin diseases such as psoriasis, prurigo and vitiligo. ...CONCLUSIONS: These findings suggest that tacalcitol reduces skin inflamma …
BACKGROUND: 1,24-Dihydroxyvitamin D3 (tacalcitol), a vitamin D(3) compound, has been used to treat T cell-mediated inflammatory skin …
The effect of long-term treatment with tacalcitol on the psoriatic epidermis. A flow cytometric analysis.
Mommers JM, Castelijns FA, Seegers BA, Van Rossum MM, Van Hooijdonk CA, Van Erp PE, Van De Kerkhof PC. Mommers JM, et al. Br J Dermatol. 1998 Sep;139(3):468-71. doi: 10.1046/j.1365-2133.1998.02411.x. Br J Dermatol. 1998. PMID: 9767292 Clinical Trial.
However, data on the long-term effect of tacalcitol on psoriatic skin are sparse. In this study, we assessed the cell characteristics of the psoriatic epidermis after treatment with tacalcitol for up to 24 weeks. ...From 11 patients who were treated wi …
However, data on the long-term effect of tacalcitol on psoriatic skin are sparse. In this study, we assessed the cell characte …
114 results