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Valproic acid inhibits angiogenesis in vitro and in vivo.
Michaelis M, Michaelis UR, Fleming I, Suhan T, Cinatl J, Blaheta RA, Hoffmann K, Kotchetkov R, Busse R, Nau H, Cinatl J Jr. Michaelis M, et al. Among authors: nau h. Mol Pharmacol. 2004 Mar;65(3):520-7. doi: 10.1124/mol.65.3.520. Mol Pharmacol. 2004. PMID: 14978230
S-2-pentyl-4-pentynoic hydroxamic acid and its metabolite s-2-pentyl-4-pentynoic acid in the NMRI-exencephaly-mouse model: pharmacokinetic profiles, teratogenic effects, and histone deacetylase inhibition abilities of further valproic acid hydroxamates and amides.
Eikel D, Hoffmann K, Zoll K, Lampen A, Nau H. Eikel D, et al. Among authors: nau h. Drug Metab Dispos. 2006 Apr;34(4):612-20. doi: 10.1124/dmd.105.008078. Epub 2006 Jan 13. Drug Metab Dispos. 2006. PMID: 16415118
Effects of valproic acid derivatives on inositol trisphosphate depletion, teratogenicity, glycogen synthase kinase-3beta inhibition, and viral replication: a screening approach for new bipolar disorder drugs derived from the valproic acid core structure.
Eickholt BJ, Towers GJ, Ryves WJ, Eikel D, Adley K, Ylinen LM, Chadborn NH, Harwood AJ, Nau H, Williams RS. Eickholt BJ, et al. Among authors: nau h. Mol Pharmacol. 2005 May;67(5):1426-33. doi: 10.1124/mol.104.009308. Epub 2005 Feb 1. Mol Pharmacol. 2005. PMID: 15687223 Free PMC article.
397 results