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Substituted 2-arylbenzothiazoles as kinase inhibitors: hit-to-lead optimization.
Tasler S, Müller O, Wieber T, Herz T, Pegoraro S, Saeb W, Lang M, Krauss R, Totzke F, Zirrgiebel U, Ehlert JE, Kubbutat MH, Schächtele C. Tasler S, et al. Among authors: zirrgiebel u. Bioorg Med Chem. 2009 Sep 15;17(18):6728-37. doi: 10.1016/j.bmc.2009.07.047. Epub 2009 Jul 25. Bioorg Med Chem. 2009. PMID: 19692247
Anti-tumor effects of AMT in the renal cell carcinoma model.
Caballero M, Scheele J, Zirrgiebel U, Esser N, Schächtele C, Soltau J, Rentschler J, Diergarten K, Drevs J. Caballero M, et al. Among authors: zirrgiebel u. Oncol Rep. 2010 Jan;23(1):205-10. Oncol Rep. 2010. PMID: 19956883
Phase I clinical study of AZD2171, an oral vascular endothelial growth factor signaling inhibitor, in patients with advanced solid tumors.
Drevs J, Siegert P, Medinger M, Mross K, Strecker R, Zirrgiebel U, Harder J, Blum H, Robertson J, Jürgensmeier JM, Puchalski TA, Young H, Saunders O, Unger C. Drevs J, et al. Among authors: zirrgiebel u. J Clin Oncol. 2007 Jul 20;25(21):3045-54. doi: 10.1200/JCO.2006.07.2066. J Clin Oncol. 2007. PMID: 17634482 Clinical Trial.
28 results