Dawson RJ - Search Results

1

Structure of the acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1.

Dawson RJ, Benz J, Stohler P, Tetaz T, Joseph C, Huber S, Schmid G, Hügin D, Pflimlin P, Trube G, Rudolph MG, Hennig M, Ruf A. Dawson RJ, et al. Nat Commun. 2012 Jul 3;3:936. doi: 10.1038/ncomms1917. Nat Commun. 2012. PMID: 22760635 Free article.

2

Ligand channel in pharmacologically stabilized rhodopsin.

Mattle D, Kuhn B, Aebi J, Bedoucha M, Kekilli D, Grozinger N, Alker A, Rudolph MG, Schmid G, Schertler GFX, Hennig M, Standfuss J, Dawson RJP. Mattle D, et al. Proc Natl Acad Sci U S A. 2018 Apr 3;115(14):3640-3645. doi: 10.1073/pnas.1718084115. Epub 2018 Mar 19. Proc Natl Acad Sci U S A. 2018. PMID: 29555765 Free PMC article.

3

Structural insights into the inhibition of glycine reuptake.

Shahsavar A, Stohler P, Bourenkov G, Zimmermann I, Siegrist M, Guba W, Pinard E, Sinning S, Seeger MA, Schneider TR, Dawson RJP, Nissen P. Shahsavar A, et al. Among authors: dawson rjp. Nature. 2021 Mar;591(7851):677-681. doi: 10.1038/s41586-021-03274-z. Epub 2021 Mar 3. Nature. 2021. PMID: 33658720

4

Identifying Conformation-Selective Heavy-Chain-Only Antibodies Against Membrane Proteins by a Thermal-Shift Scintillation Proximity Assay.

Stohler P, Dawson RJP. Stohler P, et al. Among authors: dawson rjp. Methods Mol Biol. 2020;2127:185-190. doi: 10.1007/978-1-0716-0373-4_13. Methods Mol Biol. 2020. PMID: 32112323

5

Structural Basis for Allosteric Ligand Recognition in the Human CC Chemokine Receptor 7.

Jaeger K, Bruenle S, Weinert T, Guba W, Muehle J, Miyazaki T, Weber M, Furrer A, Haenggi N, Tetaz T, Huang CY, Mattle D, Vonach JM, Gast A, Kuglstatter A, Rudolph MG, Nogly P, Benz J, Dawson RJP, Standfuss J. Jaeger K, et al. Among authors: dawson rjp. Cell. 2019 Aug 22;178(5):1222-1230.e10. doi: 10.1016/j.cell.2019.07.028. Cell. 2019. PMID: 31442409 Free PMC article.

6

Real-time monitoring of binding events on a thermostabilized human A2A receptor embedded in a lipid bilayer by surface plasmon resonance.

Bocquet N, Kohler J, Hug MN, Kusznir EA, Rufer AC, Dawson RJ, Hennig M, Ruf A, Huber W, Huber S. Bocquet N, et al. Among authors: dawson rj. Biochim Biophys Acta. 2015 May;1848(5):1224-33. doi: 10.1016/j.bbamem.2015.02.014. Epub 2015 Feb 25. Biochim Biophys Acta. 2015. PMID: 25725488 Free article.

7

Crystallization scale preparation of a stable GPCR signaling complex between constitutively active rhodopsin and G-protein.

Maeda S, Sun D, Singhal A, Foggetta M, Schmid G, Standfuss J, Hennig M, Dawson RJ, Veprintsev DB, Schertler GF. Maeda S, et al. Among authors: dawson rj. PLoS One. 2014 Jun 30;9(6):e98714. doi: 10.1371/journal.pone.0098714. eCollection 2014. PLoS One. 2014. PMID: 24979345 Free PMC article.

8

Synthetic single domain antibodies for the conformational trapping of membrane proteins.

Zimmermann I, Egloff P, Hutter CA, Arnold FM, Stohler P, Bocquet N, Hug MN, Huber S, Siegrist M, Hetemann L, Gera J, Gmür S, Spies P, Gygax D, Geertsma ER, Dawson RJ, Seeger MA. Zimmermann I, et al. Among authors: dawson rj. Elife. 2018 May 24;7:e34317. doi: 10.7554/eLife.34317. Elife. 2018. PMID: 29792401 Free PMC article.

9

Development of an antibody fragment that stabilizes GPCR/G-protein complexes.

Maeda S, Koehl A, Matile H, Hu H, Hilger D, Schertler GFX, Manglik A, Skiniotis G, Dawson RJP, Kobilka BK. Maeda S, et al. Nat Commun. 2018 Sep 13;9(1):3712. doi: 10.1038/s41467-018-06002-w. Nat Commun. 2018. PMID: 30213947 Free PMC article.

10

Structure of the µ-opioid receptor-G_i protein complex.

Koehl A, Hu H, Maeda S, Zhang Y, Qu Q, Paggi JM, Latorraca NR, Hilger D, Dawson R, Matile H, Schertler GFX, Granier S, Weis WI, Dror RO, Manglik A, Skiniotis G, Kobilka BK. Koehl A, et al. Nature. 2018 Jun;558(7711):547-552. doi: 10.1038/s41586-018-0219-7. Epub 2018 Jun 13. Nature. 2018. PMID: 29899455 Free PMC article.

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