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Discovery of ML314, a Brain Penetrant Non-Peptidic β-Arrestin Biased Agonist of the Neurotensin NTR1 Receptor.
Peddibhotla S, Hedrick MP, Hershberger P, Maloney PR, Li Y, Milewski M, Gosalia P, Gray W, Mehta A, Sugarman E, Hood B, Suyama E, Nguyen K, Heynen-Genel S, Vasile S, Salaniwal S, Stonich D, Su Y, Mangravita-Novo A, Vicchiarelli M, Roth GP, Smith LH, Chung TD, Hanson GR, Thomas JB, Caron MG, Barak LS, Pinkerton AB. Peddibhotla S, et al. Among authors: hanson gr. ACS Med Chem Lett. 2013 Jul 20;4(9):846-851. doi: 10.1021/ml400176n. ACS Med Chem Lett. 2013. PMID: 24611085 Free PMC article.
ML314: A Biased Neurotensin Receptor Ligand for Methamphetamine Abuse.
Barak LS, Bai Y, Peterson S, Evron T, Urs NM, Peddibhotla S, Hedrick MP, Hershberger P, Maloney PR, Chung TD, Rodriguiz RM, Wetsel WC, Thomas JB, Hanson GR, Pinkerton AB, Caron MG. Barak LS, et al. Among authors: hanson gr. ACS Chem Biol. 2016 Jul 15;11(7):1880-90. doi: 10.1021/acschembio.6b00291. Epub 2016 May 5. ACS Chem Biol. 2016. PMID: 27119457 Free PMC article.
Mephedrone alters basal ganglia and limbic neurotensin systems.
German CL, Hoonakker AH, Fleckenstein AE, Hanson GR. German CL, et al. Among authors: hanson gr. J Neurochem. 2014 Aug;130(3):402-7. doi: 10.1111/jnc.12727. Epub 2014 Apr 19. J Neurochem. 2014. PMID: 24678634 Free PMC article.
361 results