Wilton SD - Search Results

1

Translation from a DMD exon 5 IRES results in a functional dystrophin isoform that attenuates dystrophinopathy in humans and mice.

Wein N, Vulin A, Falzarano MS, Szigyarto CA, Maiti B, Findlay A, Heller KN, Uhlén M, Bakthavachalu B, Messina S, Vita G, Passarelli C, Brioschi S, Bovolenta M, Neri M, Gualandi F, Wilton SD, Rodino-Klapac LR, Yang L, Dunn DM, Schoenberg DR, Weiss RB, Howard MT, Ferlini A, Flanigan KM. Wein N, et al. Among authors: wilton sd. Nat Med. 2014 Sep;20(9):992-1000. doi: 10.1038/nm.3628. Epub 2014 Aug 10. Nat Med. 2014. PMID: 25108525 Free PMC article.

2

Antisense-induced exon skipping and synthesis of dystrophin in the mdx mouse.

Mann CJ, Honeyman K, Cheng AJ, Ly T, Lloyd F, Fletcher S, Morgan JE, Partridge TA, Wilton SD. Mann CJ, et al. Among authors: wilton sd. Proc Natl Acad Sci U S A. 2001 Jan 2;98(1):42-7. doi: 10.1073/pnas.98.1.42. Proc Natl Acad Sci U S A. 2001. PMID: 11120883 Free PMC article.

3

Improved antisense oligonucleotide induced exon skipping in the mdx mouse model of muscular dystrophy.

Mann CJ, Honeyman K, McClorey G, Fletcher S, Wilton SD. Mann CJ, et al. Among authors: wilton sd. J Gene Med. 2002 Nov-Dec;4(6):644-54. doi: 10.1002/jgm.295. J Gene Med. 2002. PMID: 12439856

4

Target selection for antisense oligonucleotide induced exon skipping in the dystrophin gene.

Errington SJ, Mann CJ, Fletcher S, Wilton SD. Errington SJ, et al. Among authors: wilton sd. J Gene Med. 2003 Jun;5(6):518-27. doi: 10.1002/jgm.361. J Gene Med. 2003. PMID: 12797117

5

Functional amounts of dystrophin produced by skipping the mutated exon in the mdx dystrophic mouse.

Lu QL, Mann CJ, Lou F, Bou-Gharios G, Morris GE, Xue SA, Fletcher S, Partridge TA, Wilton SD. Lu QL, et al. Among authors: wilton sd. Nat Med. 2003 Aug;9(8):1009-14. doi: 10.1038/nm897. Epub 2003 Jul 6. Nat Med. 2003. PMID: 12847521

6

Dystrophin expression in the mdx mouse after localised and systemic administration of a morpholino antisense oligonucleotide.

Fletcher S, Honeyman K, Fall AM, Harding PL, Johnsen RD, Wilton SD. Fletcher S, et al. Among authors: wilton sd. J Gene Med. 2006 Feb;8(2):207-16. doi: 10.1002/jgm.838. J Gene Med. 2006. PMID: 16285002

7

Systemic delivery of morpholino oligonucleotide restores dystrophin expression bodywide and improves dystrophic pathology.

Alter J, Lou F, Rabinowitz A, Yin H, Rosenfeld J, Wilton SD, Partridge TA, Lu QL. Alter J, et al. Among authors: wilton sd. Nat Med. 2006 Feb;12(2):175-7. doi: 10.1038/nm1345. Epub 2006 Jan 29. Nat Med. 2006. PMID: 16444267

8

Antisense oligonucleotide-induced exon skipping restores dystrophin expression in vitro in a canine model of DMD.

McClorey G, Moulton HM, Iversen PL, Fletcher S, Wilton SD. McClorey G, et al. Among authors: wilton sd. Gene Ther. 2006 Oct;13(19):1373-81. doi: 10.1038/sj.gt.3302800. Epub 2006 May 25. Gene Ther. 2006. PMID: 16724091

9

Induced dystrophin exon skipping in human muscle explants.

McClorey G, Fall AM, Moulton HM, Iversen PL, Rasko JE, Ryan M, Fletcher S, Wilton SD. McClorey G, et al. Among authors: wilton sd. Neuromuscul Disord. 2006 Oct;16(9-10):583-90. doi: 10.1016/j.nmd.2006.05.017. Epub 2006 Aug 21. Neuromuscul Disord. 2006. PMID: 16919955

10

Redirecting splicing to address dystrophin mutations: molecular by-pass surgery.

Wilton SD, Fletcher S. Wilton SD, et al. Prog Mol Subcell Biol. 2006;44:161-97. doi: 10.1007/978-3-540-34449-0_8. Prog Mol Subcell Biol. 2006. PMID: 17076269

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