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Predictive biomarkers for the efficacy of peptide vaccine treatment: based on the results of a phase II study on advanced pancreatic cancer.
Shindo Y, Hazama S, Suzuki N, Iguchi H, Uesugi K, Tanaka H, Aruga A, Hatori T, Ishizaki H, Umeda Y, Fujiwara T, Ikemoto T, Shimada M, Yoshimatsu K, Takenouchi H, Matsui H, Kanekiyo S, Iida M, Koki Y, Arima H, Furukawa H, Ueno T, Yoshino S, Fujita T, Kawakami Y, Nakamura Y, Oka M, Nagano H. Shindo Y, et al. Among authors: takenouchi h. J Exp Clin Cancer Res. 2017 Feb 28;36(1):36. doi: 10.1186/s13046-017-0509-1. J Exp Clin Cancer Res. 2017. PMID: 28241889 Free PMC article. Clinical Trial.
A phase I study of combination vaccine treatment of five therapeutic epitope-peptides for metastatic colorectal cancer; safety, immunological response, and clinical outcome.
Hazama S, Nakamura Y, Takenouchi H, Suzuki N, Tsunedomi R, Inoue Y, Tokuhisa Y, Iizuka N, Yoshino S, Takeda K, Shinozaki H, Kamiya A, Furukawa H, Oka M. Hazama S, et al. Among authors: takenouchi h. J Transl Med. 2014 Mar 10;12:63. doi: 10.1186/1479-5876-12-63. J Transl Med. 2014. PMID: 24612787 Free PMC article. Clinical Trial.
A phase ΙI study of five peptides combination with oxaliplatin-based chemotherapy as a first-line therapy for advanced colorectal cancer (FXV study).
Hazama S, Nakamura Y, Tanaka H, Hirakawa K, Tahara K, Shimizu R, Ozasa H, Etoh R, Sugiura F, Okuno K, Furuya T, Nishimura T, Sakata K, Yoshimatsu K, Takenouchi H, Tsunedomi R, Inoue Y, Kanekiyo S, Shindo Y, Suzuki N, Yoshino S, Shinozaki H, Kamiya A, Furukawa H, Yamanaka T, Fujita T, Kawakami Y, Oka M. Hazama S, et al. Among authors: takenouchi h. J Transl Med. 2014 Apr 30;12:108. doi: 10.1186/1479-5876-12-108. J Transl Med. 2014. PMID: 24884643 Free PMC article. Clinical Trial.
Predictive biomarkers for the outcome of vaccination of five therapeutic epitope peptides for colorectal cancer.
Hazama S, Takenouchi H, Tsunedomi R, Iida M, Suzuki N, Iizuka N, Inoue Y, Sakamoto K, Nakao M, Shindo Y, Kanekiyo S, Tokumitsu Y, Yoshimura K, Maeda N, Maeda K, Maeda Y, Matsui H, Yoshino S, Nakamura Y, Fujita Y, Hamamoto Y, Okamoto M, Fujita T, Kawakami Y, Oka M. Hazama S, et al. Among authors: takenouchi h. Anticancer Res. 2014 Aug;34(8):4201-5. Anticancer Res. 2014. PMID: 25075047
Prediction of the efficacy of immunotherapy by measuring the integrity of cell-free DNA in plasma in colorectal cancer.
Kitahara M, Hazama S, Tsunedomi R, Takenouchi H, Kanekiyo S, Inoue Y, Nakajima M, Tomochika S, Tokuhisa Y, Iida M, Sakamoto K, Suzuki N, Takeda S, Ueno T, Yamamoto S, Yoshino S, Nagano H. Kitahara M, et al. Among authors: takenouchi h. Cancer Sci. 2016 Dec;107(12):1825-1829. doi: 10.1111/cas.13085. Epub 2016 Dec 18. Cancer Sci. 2016. PMID: 27663862 Free PMC article.
Phase II clinical trial of peptide cocktail therapy for patients with advanced pancreatic cancer: VENUS-PC study.
Suzuki N, Hazama S, Iguchi H, Uesugi K, Tanaka H, Hirakawa K, Aruga A, Hatori T, Ishizaki H, Umeda Y, Fujiwara T, Ikemoto T, Shimada M, Yoshimatsu K, Shimizu R, Hayashi H, Sakata K, Takenouchi H, Matsui H, Shindo Y, Iida M, Koki Y, Arima H, Furukawa H, Ueno T, Yoshino S, Nakamura Y, Oka M, Nagano H. Suzuki N, et al. Among authors: takenouchi h. Cancer Sci. 2017 Jan;108(1):73-80. doi: 10.1111/cas.13113. Epub 2016 Dec 19. Cancer Sci. 2017. PMID: 27783849 Free PMC article. Clinical Trial.
MicroRNA-6826 and -6875 in plasma are valuable non‑invasive biomarkers that predict the efficacy of vaccine treatment against metastatic colorectal cancer.
Kijima T, Hazama S, Tsunedomi R, Tanaka H, Takenouchi H, Kanekiyo S, Inoue Y, Nakashima M, Iida M, Sakamoto K, Suzuki N, Takeda S, Ueno T, Yamamoto S, Yoshino S, Okuno K, Nagano H. Kijima T, et al. Among authors: takenouchi h. Oncol Rep. 2017 Jan;37(1):23-30. doi: 10.3892/or.2016.5267. Epub 2016 Nov 22. Oncol Rep. 2017. PMID: 27878288 Free PMC article. Clinical Trial.
miR-196b, miR-378a and miR-486 are predictive biomarkers for the efficacy of vaccine treatment in colorectal cancer.
Shindo Y, Hazama S, Nakamura Y, Inoue Y, Kanekiyo S, Suzuki N, Takenouchi H, Tsunedomi R, Nakajima M, Ueno T, Takeda S, Yoshino S, Okuno K, Fujita Y, Hamamoto Y, Kawakami Y, Oka M, Nagano H. Shindo Y, et al. Among authors: takenouchi h. Oncol Lett. 2017 Aug;14(2):1355-1362. doi: 10.3892/ol.2017.6303. Epub 2017 Jun 2. Oncol Lett. 2017. PMID: 28789351 Free PMC article.
miR-125b-1 and miR-378a are predictive biomarkers for the efficacy of vaccine treatment against colorectal cancer.
Tanaka H, Hazama S, Iida M, Tsunedomi R, Takenouchi H, Nakajima M, Tokumitsu Y, Kanekiyo S, Shindo Y, Tomochika S, Tokuhisa Y, Sakamoto K, Suzuki N, Takeda S, Yamamoto S, Yoshino S, Ueno T, Hamamoto Y, Fujita Y, Tanaka H, Tahara K, Shimizu R, Okuno K, Fujita K, Kuroda M, Nakamura Y, Nagano H. Tanaka H, et al. Among authors: takenouchi h. Cancer Sci. 2017 Nov;108(11):2229-2238. doi: 10.1111/cas.13390. Epub 2017 Sep 22. Cancer Sci. 2017. PMID: 28859241 Free PMC article. Clinical Trial.
IgG response to MHC class I epitope peptides is a quantitative predictive biomarker in the early course of treatment of colorectal cancer using therapeutic peptides.
Kanekiyo S, Hazama S, Takenouchi H, Nakajima M, Shindo Y, Matsui H, Tokumitsu Y, Tomochika S, Tsunedomi R, Tokuhisa Y, Iida M, Sakamoto K, Suzuki N, Takeda S, Yamamoto S, Yoshino S, Okuno K, Udaka K, Kawakami Y, Matsueda S, Ito K, Nagano H. Kanekiyo S, et al. Among authors: takenouchi h. Oncol Rep. 2018 May;39(5):2385-2392. doi: 10.3892/or.2018.6288. Epub 2018 Mar 1. Oncol Rep. 2018. PMID: 29498403 Clinical Trial.
79 results