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56 results

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Page 1
Condition-dependent transcriptome reveals high-level regulatory architecture in Bacillus subtilis.
Nicolas P, Mäder U, Dervyn E, Rochat T, Leduc A, Pigeonneau N, Bidnenko E, Marchadier E, Hoebeke M, Aymerich S, Becher D, Bisicchia P, Botella E, Delumeau O, Doherty G, Denham EL, Fogg MJ, Fromion V, Goelzer A, Hansen A, Härtig E, Harwood CR, Homuth G, Jarmer H, Jules M, Klipp E, Le Chat L, Lecointe F, Lewis P, Liebermeister W, March A, Mars RA, Nannapaneni P, Noone D, Pohl S, Rinn B, Rügheimer F, Sappa PK, Samson F, Schaffer M, Schwikowski B, Steil L, Stülke J, Wiegert T, Devine KM, Wilkinson AJ, van Dijl JM, Hecker M, Völker U, Bessières P, Noirot P. Nicolas P, et al. Among authors: mader u. Science. 2012 Mar 2;335(6072):1103-6. doi: 10.1126/science.1206848. Science. 2012. PMID: 22383849
Here, we report the transcriptomes of Bacillus subtilis exposed to a wide range of environmental and nutritional conditions that the organism might encounter in nature. ...
Here, we report the transcriptomes of Bacillus subtilis exposed to a wide range of environmental and nutritional conditions that the …
The Bacillus subtilis Minimal Genome Compendium.
Michalik S, Reder A, Richts B, Faßhauer P, Mäder U, Pedreira T, Poehlein A, van Heel AJ, van Tilburg AY, Altenbuchner J, Klewing A, Reuß DR, Daniel R, Commichau FM, Kuipers OP, Hamoen LW, Völker U, Stülke J. Michalik S, et al. Among authors: mader u. ACS Synth Biol. 2021 Oct 15;10(10):2767-2771. doi: 10.1021/acssynbio.1c00339. Epub 2021 Sep 29. ACS Synth Biol. 2021. PMID: 34587446
Here, we provide a database of 105 fully annotated genomes of a series of strains with sequential deletion steps of the industrially relevant model bacterium Bacillus subtilis starting with the laboratory wild type strain B. subtilis 168 and ending with B. subtilis PG38, w …
Here, we provide a database of 105 fully annotated genomes of a series of strains with sequential deletion steps of the industrially relevan …
RNA degradation in Bacillus subtilis: an interplay of essential endo- and exoribonucleases.
Lehnik-Habrink M, Lewis RJ, Mäder U, Stülke J. Lehnik-Habrink M, et al. Among authors: mader u. Mol Microbiol. 2012 Jun;84(6):1005-17. doi: 10.1111/j.1365-2958.2012.08072.x. Epub 2012 May 8. Mol Microbiol. 2012. PMID: 22568516 Free article. Review.
Recent research on the model Gram-positive organism, Bacillus subtilis, has identified the essential RNases J1 and Y as crucial enzymes in RNA degradation. ...
Recent research on the model Gram-positive organism, Bacillus subtilis, has identified the essential RNases J1 and Y as crucial enzym …
Enhancing bacterial fitness and recombinant enzyme yield by engineering the quality control protease HtrA of Bacillus subtilis.
Öktem A, Núñez-Nepomuceno D, Ferrero-Bordera B, Walgraeve J, Seefried M, Gesell Salazar M, Steil L, Michalik S, Maaß S, Becher D, Mäder U, Völker U, van Dijl JM. Öktem A, et al. Among authors: mader u. Microbiol Spectr. 2023 Dec 12;11(6):e0177823. doi: 10.1128/spectrum.01778-23. Epub 2023 Oct 11. Microbiol Spectr. 2023. PMID: 37819116 Free PMC article.
In the expanding market of recombinant proteins, microbial cell factories such as Bacillus subtilis are key players. Microbial cell factories experience secretion stress during high-level production of secreted proteins, which can negatively impact product yield and cell v …
In the expanding market of recombinant proteins, microbial cell factories such as Bacillus subtilis are key players. Microbial cell f …
The Disulfide Stress Response and Protein S-thioallylation Caused by Allicin and Diallyl Polysulfanes in Bacillus subtilis as Revealed by Transcriptomics and Proteomics.
Chi BK, Huyen NTT, Loi VV, Gruhlke MCH, Schaffer M, Mäder U, Maaß S, Becher D, Bernhardt J, Arbach M, Hamilton CJ, Slusarenko AJ, Antelmann H. Chi BK, et al. Among authors: mader u. Antioxidants (Basel). 2019 Nov 29;8(12):605. doi: 10.3390/antiox8120605. Antioxidants (Basel). 2019. PMID: 31795512 Free PMC article.
Here, we investigated the transcriptome and protein S-thioallylomes under allicin and diallyl tetrasulfane (DAS4) exposure in the Gram-positive bacterium Bacillus subtilis. Allicin and DAS4 caused a similar thiol-specific oxidative stress response, protein and DNA damage a …
Here, we investigated the transcriptome and protein S-thioallylomes under allicin and diallyl tetrasulfane (DAS4) exposure in the Gram-posit …
Essentiality of c-di-AMP in Bacillus subtilis: Bypassing mutations converge in potassium and glutamate homeostasis.
Krüger L, Herzberg C, Rath H, Pedreira T, Ischebeck T, Poehlein A, Gundlach J, Daniel R, Völker U, Mäder U, Stülke J. Krüger L, et al. Among authors: mader u. PLoS Genet. 2021 Jan 22;17(1):e1009092. doi: 10.1371/journal.pgen.1009092. eCollection 2021 Jan. PLoS Genet. 2021. PMID: 33481774 Free PMC article.
In addition to the well-established role of this second messenger in the control of potassium homeostasis, we observed that glutamate is as toxic as potassium for a c-di-AMP-free strain of the Gram-positive model bacterium Bacillus subtilis. In this work, we isolated suppr …
In addition to the well-established role of this second messenger in the control of potassium homeostasis, we observed that glutamate is as …
Connecting parts with processes: SubtiWiki and SubtiPathways integrate gene and pathway annotation for Bacillus subtilis.
Lammers CR, Flórez LA, Schmeisky AG, Roppel SF, Mäder U, Hamoen L, Stülke J. Lammers CR, et al. Among authors: mader u. Microbiology (Reading). 2010 Mar;156(Pt 3):849-859. doi: 10.1099/mic.0.035790-0. Epub 2009 Dec 3. Microbiology (Reading). 2010. PMID: 19959575 Free article.
Bacillus subtilis is the model organism for a large group of Gram-positive bacteria, the Firmicutes. ...
Bacillus subtilis is the model organism for a large group of Gram-positive bacteria, the Firmicutes. ...
Analyses of competent and non-competent subpopulations of Bacillus subtilis reveal yhfW, yhxC and ncRNAs as novel players in competence.
Boonstra M, Schaffer M, Sousa J, Morawska L, Holsappel S, Hildebrandt P, Sappa PK, Rath H, de Jong A, Lalk M, Mäder U, Völker U, Kuipers OP. Boonstra M, et al. Among authors: mader u. Environ Microbiol. 2020 Jun;22(6):2312-2328. doi: 10.1111/1462-2920.15005. Epub 2020 Apr 15. Environ Microbiol. 2020. PMID: 32249531 Free PMC article.
Upon competence-inducing nutrient-limited conditions, only part of the Bacillus subtilis population becomes competent. Here, we separated the two subpopulations by fluorescence-assisted cell sorting (FACS). ...
Upon competence-inducing nutrient-limited conditions, only part of the Bacillus subtilis population becomes competent. Here, we separ …
SubtiWiki 2.0--an integrated database for the model organism Bacillus subtilis.
Michna RH, Zhu B, Mäder U, Stülke J. Michna RH, et al. Among authors: mader u. Nucleic Acids Res. 2016 Jan 4;44(D1):D654-62. doi: 10.1093/nar/gkv1006. Epub 2015 Oct 3. Nucleic Acids Res. 2016. PMID: 26433225 Free PMC article.
Here, we present SubtiWiki 2.0, the integrated database for the model bacterium Bacillus subtilis (http://subtiwiki.uni-goettingen.de/). SubtiWiki provides text-based access to published information about the genes and proteins of B. subtilis as well as presentations of me …
Here, we present SubtiWiki 2.0, the integrated database for the model bacterium Bacillus subtilis (http://subtiwiki.uni-goettingen.de …
56 results