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Year Number of Results
2001 1
2002 3
2003 1
2004 2
2007 2
2008 2
2009 5
2010 5
2011 10
2012 6
2013 1
2014 3
2015 2
2016 5
2017 3
2018 1
2019 1
2020 4
2021 5
2022 0
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53 results
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Condition-dependent transcriptome reveals high-level regulatory architecture in Bacillus subtilis.
Nicolas P, Mäder U, Dervyn E, Rochat T, Leduc A, Pigeonneau N, Bidnenko E, Marchadier E, Hoebeke M, Aymerich S, Becher D, Bisicchia P, Botella E, Delumeau O, Doherty G, Denham EL, Fogg MJ, Fromion V, Goelzer A, Hansen A, Härtig E, Harwood CR, Homuth G, Jarmer H, Jules M, Klipp E, Le Chat L, Lecointe F, Lewis P, Liebermeister W, March A, Mars RA, Nannapaneni P, Noone D, Pohl S, Rinn B, Rügheimer F, Sappa PK, Samson F, Schaffer M, Schwikowski B, Steil L, Stülke J, Wiegert T, Devine KM, Wilkinson AJ, van Dijl JM, Hecker M, Völker U, Bessières P, Noirot P. Nicolas P, et al. Among authors: mader u. Science. 2012 Mar 2;335(6072):1103-6. doi: 10.1126/science.1206848. Science. 2012. PMID: 22383849
Bacteria adapt to environmental stimuli by adjusting their transcriptomes in a complex manner, the full potential of which has yet to be established for any individual bacterial species. Here, we report the transcriptomes of Bacillus subtilis exposed to a wide range of env …
Bacteria adapt to environmental stimuli by adjusting their transcriptomes in a complex manner, the full potential of which has yet to be est …
The Bacillus subtilis Minimal Genome Compendium.
Michalik S, Reder A, Richts B, Faßhauer P, Mäder U, Pedreira T, Poehlein A, van Heel AJ, van Tilburg AY, Altenbuchner J, Klewing A, Reuß DR, Daniel R, Commichau FM, Kuipers OP, Hamoen LW, Völker U, Stülke J. Michalik S, et al. Among authors: mader u. ACS Synth Biol. 2021 Oct 15;10(10):2767-2771. doi: 10.1021/acssynbio.1c00339. Epub 2021 Sep 29. ACS Synth Biol. 2021. PMID: 34587446
Here, we provide a database of 105 fully annotated genomes of a series of strains with sequential deletion steps of the industrially relevant model bacterium Bacillus subtilis starting with the laboratory wild type strain B. subtilis 168 and ending with B. subtilis PG38, w …
Here, we provide a database of 105 fully annotated genomes of a series of strains with sequential deletion steps of the industrially relevan …
RNA degradation in Bacillus subtilis: an interplay of essential endo- and exoribonucleases.
Lehnik-Habrink M, Lewis RJ, Mäder U, Stülke J. Lehnik-Habrink M, et al. Among authors: mader u. Mol Microbiol. 2012 Jun;84(6):1005-17. doi: 10.1111/j.1365-2958.2012.08072.x. Epub 2012 May 8. Mol Microbiol. 2012. PMID: 22568516 Free article. Review.
By contrast, Gram-positive bacteria do not possess several important players of E. coli RNA degradation, most notably the essential enzyme RNase E. Recent research on the model Gram-positive organism, Bacillus subtilis, has identified the essential RNases J1 and Y as cruci …
By contrast, Gram-positive bacteria do not possess several important players of E. coli RNA degradation, most notably the essential enzyme R …
The Disulfide Stress Response and Protein S-thioallylation Caused by Allicin and Diallyl Polysulfanes in Bacillus subtilis as Revealed by Transcriptomics and Proteomics.
Chi BK, Huyen NTT, Loi VV, Gruhlke MCH, Schaffer M, Mäder U, Maaß S, Becher D, Bernhardt J, Arbach M, Hamilton CJ, Slusarenko AJ, Antelmann H. Chi BK, et al. Among authors: mader u. Antioxidants (Basel). 2019 Nov 29;8(12):605. doi: 10.3390/antiox8120605. Antioxidants (Basel). 2019. PMID: 31795512 Free PMC article.
Here, we investigated the transcriptome and protein S-thioallylomes under allicin and diallyl tetrasulfane (DAS4) exposure in the Gram-positive bacterium Bacillus subtilis. Allicin and DAS4 caused a similar thiol-specific oxidative stress response, protein and DNA damage a …
Here, we investigated the transcriptome and protein S-thioallylomes under allicin and diallyl tetrasulfane (DAS4) exposure in the Gram-posit …
Essentiality of c-di-AMP in Bacillus subtilis: Bypassing mutations converge in potassium and glutamate homeostasis.
Krüger L, Herzberg C, Rath H, Pedreira T, Ischebeck T, Poehlein A, Gundlach J, Daniel R, Völker U, Mäder U, Stülke J. Krüger L, et al. Among authors: mader u. PLoS Genet. 2021 Jan 22;17(1):e1009092. doi: 10.1371/journal.pgen.1009092. eCollection 2021 Jan. PLoS Genet. 2021. PMID: 33481774 Free PMC article.
In addition to the well-established role of this second messenger in the control of potassium homeostasis, we observed that glutamate is as toxic as potassium for a c-di-AMP-free strain of the Gram-positive model bacterium Bacillus subtilis. In this work, we isolated suppr …
In addition to the well-established role of this second messenger in the control of potassium homeostasis, we observed that glutamate is as …
Genoscapist: online exploration of quantitative profiles along genomes via interactively customized graphical representations.
Dérozier S, Nicolas P, Mäder U, Guérin C. Dérozier S, et al. Among authors: mader u. Bioinformatics. 2021 Feb 3:btab079. doi: 10.1093/bioinformatics/btab079. Online ahead of print. Bioinformatics. 2021. PMID: 33532816
Relevance is demonstrated by deployment of two websites dedicated to large condition-dependent transcriptome datasets available for Bacillus subtilis and Staphylococcus aureus. AVAILABILITY: Websites and source code freely accessible at https://genoscapist.migale.inrae.fr. …
Relevance is demonstrated by deployment of two websites dedicated to large condition-dependent transcriptome datasets available for Bacil
Analyses of competent and non-competent subpopulations of Bacillus subtilis reveal yhfW, yhxC and ncRNAs as novel players in competence.
Boonstra M, Schaffer M, Sousa J, Morawska L, Holsappel S, Hildebrandt P, Sappa PK, Rath H, de Jong A, Lalk M, Mäder U, Völker U, Kuipers OP. Boonstra M, et al. Among authors: mader u. Environ Microbiol. 2020 Jun;22(6):2312-2328. doi: 10.1111/1462-2920.15005. Epub 2020 Apr 15. Environ Microbiol. 2020. PMID: 32249531 Free PMC article.
Upon competence-inducing nutrient-limited conditions, only part of the Bacillus subtilis population becomes competent. Here, we separated the two subpopulations by fluorescence-assisted cell sorting (FACS). ...
Upon competence-inducing nutrient-limited conditions, only part of the Bacillus subtilis population becomes competent. Here, we separ …
Double trouble: Bacillus depends on a functional Tat machinery to avoid severe oxidative stress and starvation upon entry into a NaCl-depleted environment.
Prajapati B, Bernal-Cabas M, López-Álvarez M, Schaffer M, Bartel J, Rath H, Steil L, Becher D, Völker U, Mäder U, van Dijl JM. Prajapati B, et al. Among authors: mader u. Biochim Biophys Acta Mol Cell Res. 2021 Feb;1868(2):118914. doi: 10.1016/j.bbamcr.2020.118914. Epub 2020 Nov 25. Biochim Biophys Acta Mol Cell Res. 2021. PMID: 33245978 Free article.
In doing so, these translocases serve different biological functions ranging from energy conversion to cell division. In the Gram-positive soil bacterium Bacillus subtilis, the Tat machinery is essential for effective growth in media lacking iron or NaCl. ...
In doing so, these translocases serve different biological functions ranging from energy conversion to cell division. In the Gram-positive s …
Impact of high salinity and the compatible solute glycine betaine on gene expression of Bacillus subtilis.
Rath H, Sappa PK, Hoffmann T, Gesell Salazar M, Reder A, Steil L, Hecker M, Bremer E, Mäder U, Völker U. Rath H, et al. Among authors: mader u. Environ Microbiol. 2020 Aug;22(8):3266-3286. doi: 10.1111/1462-2920.15087. Epub 2020 Jun 8. Environ Microbiol. 2020. PMID: 32419322
The Gram-positive bacterium Bacillus subtilis is frequently exposed to hyperosmotic conditions. ...
The Gram-positive bacterium Bacillus subtilis is frequently exposed to hyperosmotic conditions. ...
53 results