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Therapy with proton-pump inhibitors for gastroesophageal reflux disease does not reduce the risk for severe exacerbations in COPD.

Baumeler L, Papakonstantinou E, Milenkovic B, Lacoma A, Louis R, Aerts JG, Welte T, Kostikas K, Blasi F, Boersma W, Torres A, Rohde GG, Boeck L, Rakic J, Scherr A, Tamm M, Stolz D. Baumeler L, et al. Respirology. 2016 Jul;21(5):883-90. doi: 10.1111/resp.12758. Epub 2016 Mar 11. Respirology. 2016. PMID: 26970108 Free article.

Proton pump inhibitors use is associated with a lower risk of acute exacerbation and mortality in patients with coexistent COPD and GERD.

Su VY, Liao HF, Perng DW, Chou YC, Hsu CC, Chou CL, Chang YL, Yen JC, Chen TJ, Chou TC. Su VY, et al. Int J Chron Obstruct Pulmon Dis. 2018 Sep 19;13:2907-2915. doi: 10.2147/COPD.S157761. eCollection 2018. Int J Chron Obstruct Pulmon Dis. 2018. PMID: 30275689 Free PMC article.

Association of gastroesophageal reflux disease risk with exacerbations of chronic obstructive pulmonary disease.

Liang B, Wang M, Yi Q, Feng Y. Liang B, et al. Dis Esophagus. 2013 Aug;26(6):557-60. doi: 10.1111/dote.12014. Epub 2013 Jan 10. Dis Esophagus. 2013. PMID: 23301861

Proportion of gastroesophageal reflux symptoms in patients with chronic obstructive pulmonary disease.

Phulpoto MA, Qayyum S, Rizvi N, Khuhawar SM. Phulpoto MA, et al. J Pak Med Assoc. 2005 Jul;55(7):276-9. J Pak Med Assoc. 2005. PMID: 16108509

Impact of self-reported gastroesophageal reflux disease in subjects from COPDGene cohort.

Martinez CH, Okajima Y, Murray S, Washko GR, Martinez FJ, Silverman EK, Lee JH, Regan EA, Crapo JD, Curtis JL, Hatabu H, Han MK; COPDGene Investigators. Martinez CH, et al. Respir Res. 2014 Jun 3;15(1):62. doi: 10.1186/1465-9921-15-62. Respir Res. 2014. PMID: 24894541 Free PMC article. Clinical Trial.

Impact of gastroesophageal reflux on longitudinal lung function and quantitative computed tomography in the COPDGene cohort.

Baldomero AK, Wendt CH, Petersen A, Gaeckle NT, Han MK, Kunisaki KM; COPDGene Investigators. Baldomero AK, et al. Respir Res. 2020 Aug 3;21(1):203. doi: 10.1186/s12931-020-01469-y. Respir Res. 2020. PMID: 32746820 Free PMC article. Clinical Trial.

Do frequent moderate exacerbations contribute to progression of chronic obstructive pulmonary disease in patients who are ex-smokers?

Dreyse J, Díaz O, Repetto PB, Morales A, Saldías F, Lisboa C. Dreyse J, et al. Int J Chron Obstruct Pulmon Dis. 2015 Mar 10;10:525-33. doi: 10.2147/COPD.S76475. eCollection 2015. Int J Chron Obstruct Pulmon Dis. 2015. PMID: 25792820 Free PMC article.

Associations between gastro-oesophageal reflux, its management and exacerbations of chronic obstructive pulmonary disease.

Benson VS, Müllerová H, Vestbo J, Wedzicha JA, Patel A, Hurst JR; Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators. Benson VS, et al. Respir Med. 2015 Sep;109(9):1147-54. doi: 10.1016/j.rmed.2015.06.009. Epub 2015 Jun 23. Respir Med. 2015. PMID: 26166017 Free article.

Gastroesophageal reflux disease in chronic obstructive pulmonary disease.

Tanimura K, Muro S. Tanimura K, et al. Respir Investig. 2024 Sep;62(5):746-758. doi: 10.1016/j.resinv.2024.06.004. Epub 2024 Jun 27. Respir Investig. 2024. PMID: 38941760 Review.

The cross-sectional and longitudinal association of the BODE index with quality of life in patients with chronic obstructive pulmonary disease.

Lin YX, Xu WN, Liang LR, Pang BS, Nie XH, Zhang J, Wang H, Liu YX, Wang DQ, Xu ZY, Wang HW, Zhang HS, He ZY, Yang T, Wang C. Lin YX, et al. Chin Med J (Engl). 2009 Dec 20;122(24):2939-44. Chin Med J (Engl). 2009. PMID: 20137478

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